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NTIS 바로가기대한한방내과학회지 = The journal of internal Korean medicine, v.39 no.4, 2018년, pp.451 - 462
나가영 (동신대학교 한의과대학 내과학교실) , 이혜인 (동신대학교 한의과대학 내과학교실) , 김영광 (동신대학교 한의과대학 내과학교실) , 문영호 (동신대학교 한의과대학 내과학교실)
Hubakmawhang-tang (HMT), listed in Geumgweyoryak, is an oriental medicine used for the symptoms of asthma, such as cough and dyspnea. In this study, we investigated the HMT effects on ovalbumin-induced asthmatic in mice. We examined weight changes, airway hyperresponsiveness, histopathological abnor...
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핵심어 | 질문 | 논문에서 추출한 답변 |
---|---|---|
천식은 무엇인가? | 천식은 여러 세포 및 세포인자가 작용하여 생긴 기도의 만성 염증질환이다1. 대부분의 기류 장애는 가역적이나 천식이 적절히 치료되지 않고 오래 지속되면 폐기능이 저하되고, 비가역적인 기도폐쇄가 발생할 수 있다2,3. | |
천식이 오래 지속되면 신체에 어떤 변화가 발생할 수 있는가? | 천식은 여러 세포 및 세포인자가 작용하여 생긴 기도의 만성 염증질환이다1. 대부분의 기류 장애는 가역적이나 천식이 적절히 치료되지 않고 오래 지속되면 폐기능이 저하되고, 비가역적인 기도폐쇄가 발생할 수 있다2,3. |
Yu SH. Manual of Pulmonology. 1st edition. Seoul: Daehan medical publishing; 2012, p. 116.
Kim SH. Airway epithelial cells in airway inflammation and remodeling in asthma. Allergy Asthma Respir Dis 2016;4(2):82-90.
Davey P. Medicine at a glance. 2nd edition. Seoul: E public; 2010, p. 189-90.
GINA. Global Strategy for Asthma Management and Prevention (Uptated 2017). 2017:14. Available from: URL:http://www.ginasthma.org..
WHO. Asthma fact sheet Updated April 2017. Available from: URL:http://www.who.int/mediacentre /factsheets/fs307/en/ [accessed on 23 November 2017]
Department of Pulmonary Internal Medicine, College of Korean Medicine. Pulmonary Internal Medicine. 1st edition. Seoul: Nado Publishing; 2011, p. 102-15, 321-28.
Yang SS. Geumgweyoryak. 1st edition. Seoul: Aulos Publishing; 1994, p. 189-90.
Lee KY. Bigeub Cheongeumyobang Gyoyeog. 1st edition. Beijing: People's medical publishing house; 1997, p. 297.
Choi JB. Medicine of Internal organs. 1st edition. Gyungsan: Gyungsan University Publishing; 1995, p. 75.
Seo BS, Park YK. Effect of Cassiae semen extract on ovalbumin-induced allergic astma in mice. Kor J Herbol 2015;30(1):25-32.
Kang SY, Park YK. Effect of Agastachis Herba extract on OVA-induced allergic asthma in mice. Kor J Herbol 2015;30(3):1-12.
Jung JK. Effects of modified-Okbyungpoongsan in allergic asthma. Graduate School of Dongguk University. 2017.
Jeong DH, Kim JH, Park SY, Choi JH. Effects of Pinelliae Rizoma(PR) on asthma induced intra-nasal instillation of ovalbumin in mice. The Journal of Koran Oriental Medical Ophthalmology & Otolaryngology & Dermatology 2008;21(1):38-54.
Ju CY, Jung HJ, Jung SK, Rhee HK. Armeniacae Amarum Semen Contributes to the Chemotaxis of Eosinophils and Secretion of Chemokines in A549 Human Epithelial Cells. Kor J Orient Int Med 2006;27(1):208-20.
Jung JY, Jung SK, Jung HJ, Rhee HK. Microarray Analysis of Gene Expression Profile by Treatment of Schizandrae fructus Extract in Inflammationinduced Human Epithelial A549 Cells. Kor J Orient Int Med 2008;29(3):543-53.
Park YS. Analysis of Pharmacology in Korean Medicine. 2nd edition. Seoul: Academy Publishing; 2002, p. 1344-7.
Seo JU. Hubakmahwang-Tang and Its Component, Magnolol Enhanced the Anti-Cancer Activity in Human Lung Cancer Cells. Department of Cancer Preventive Material Development. Graduate School of Kyunghee University 2010.
Kim HW. Combination treatment with Socheongryong-Tang, a herbal medicine, and prednisolone reduces inflammation and hyperresponsiveness of the airway in asthmatic mice : via regulation of Th2 skewing cytokines and antigen specific antibody production. Graduate School of Dongshin University 2007.
Hamelmann E, Schwarze J, Takeda K, Oshiba A, Larsen GL, Irvin CG, et al. Noninvasive Measurement of Airway Responsiveness in Allergic Mice Using Barometric Plethysmography. Am J Respir Crit Care Med 1997;156(3 Pt 1):766-75.
Kim KM, Jee YK. Update on the management of bronchial asthma. Kor J Orient Int Med 2010;78(6):697-702.
Oh G. Book 1 of Uijonggeumgam. 1st edition. Seoul: Daesung Publishing; 1991, p. 487.
Kim DH, Kim HM, Ryu JH, Kim SC, Yang JH, Hong SH, et al. Oriental pharmacy. 4th edition. Seoul: Shinilbooks; 2015, p. 229-31, 753-59, 831-37.
Kim H, Ahn YT, Kim YS, Cho SI, An WG. Antiasthmatic effects of schizandrae fructus extract in mice with asthma. Pharmacogn Mag 2014;10(1):80-5.
Smith JG Jr, Wehr RF, Chalker DK. Corticosteroidinduced cutaneous atrophy and telangiectasia: experimental production associated with weight loss in rats. Arch Dermatol 1976;112(8):1115-7.
Hargreave FE, Ryan G, Thomson NC, O'Byrne PM, Latimer K, Juniper EF, et al. Bronchial responsiveness to histamine or methacholine in asthma: measurement and clinical significance. J Allergy Clin Immunol 1981;68(5):347-55.
Kim GH, Seo KJ, Byeon JH, Song DJ, Yoo Y, Choung JT, et al. Changes in Bronchial Hyperresponsiveness in Children with Asthma. Pediatr Allergy Respir Dis (Korea) 2007;17(3) :196-205.
Kim YI, Park DJ, Kim YJ, Cho DH, Jee SY, Choi JS, et al. Etiologic Factors for Methacholine Upper Airway Hyperresponsiveness and Upper Airway Obstruction. Asthma and allergy 2010; 30(1):21-9.
Bullone M, Lavoie JP. Asthma of horses and men: how can equine heaves help us better understand human asthma immunopathology and its functional consequences? Mol Immunol 2015;66(1):97-105.
Kindt T, Glodsby R, Osborn B. Kuby immunology. 6th edition. New York: W. H. Freeman and Company; 2006, p. 289-91.
Balzar S, Strand M, Rhodes D, Wenzel SE. IgE expression pattern in lung: Relation to systemic IgE and asthma phenotypes. J Allergy Clin Immunol 2007;119(4):855-62.
Chakir J, Shannon J, Molet S, Fukakusa M, Elias J, Laviolette M, et al. Airway remodelingassociated mediators in moderate to severe asthma: effect of steroids on TGF-beta, IL-11, IL-17, and type I and type III collagen expression. J Allergy Clin Immunol 2003;111(6):1293-8.
Wen MC, Wei CH, Hu ZQ, Srivastava K, Ko J, Xi ST, et al. Efficacy and tolerability of anti-asthma herbal medicine intervention in adult patients with moderate-severe allergic asthma. J Allergy Clin Immunol 2005;116(3):517-24.
Lynch EL, Little FF, Wilson KC, Center DM, Cruikshank WW. Immuno-modulatory cytokines in asthmatic inflammation. Cytokine Growth Factor Rev 2003;14(6):489-502.
Medoff BD, Sauty A, Tager AM, Maclean JA, Smith RN, Mathew A, et al. IFN-gammainducible protein 10(CXCL10) contributes to airway hyperreactivity and airway inflammation in a mouse model of asthma. J Immunol 2002; 168(10):5278-86.
Wardlaw AJ, Brightling CE, Green R, Woltmann G, Bradding P, Pavord ID. New insights into the relationship between airway inflammation and asthma. Clin Sci(Lond) 2002;103(2):201-11.
Corry DB, Folkesson HG, Warnock ML, Erle DJ, Matthay MA, Locksley RM, et al. Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity. J Exp Med 1996;183(1):109-17.
Isselbacher KJ, Braunwald E, Wilson JD, Martin JB, Fauci AS, Kasper DL, et al. Principles of Internal Medicine. 11th edition. New York: McGraw-Hill Education; 1987, p. 1757-77.
Lee HJ, Jo S, Ryu J, Jeong HS, Lee G, Ryu MH, et al. Effects of Schisandra chinensis Turcz. fruit on contact dermatitis induced by dinitrofluorobenzene in mice. Mol Med Rep 2015;12(2):2135-9.
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