[논문]A Review of Pharmacopuncture Treatment for Frozen Shoulder: A Literature Review of Clinical Trials

Jeong, Seong-Mok; Kim, Sung-Jin; Yoon, Jin-Young; Lee, Chang Hee; Shim, Sung-Eun; Kim, Jeong Hyon; Goo, Bon Hyuk; Park, Yeon-Cheol; Seo, Byung-Kwan; Nam, Sang-soo; Baek, Yong-Hyeon

doi:10.13045/jar.2018.00262

A Review of Pharmacopuncture Treatment for Frozen Shoulder: A Literature Review of Clinical Trials 원문보기

Journal of acupuncture research, v.35 no.4, 2018년, pp.169 - 175

Jeong, Seong-Mok (Department of Acupuncture and Moxibustion, Kyung Hee University Korean Medicine Hospital at Gangdong) , Kim, Sung-Jin (Department of Acupuncture and Moxibustion, Kyung Hee University Korean Medicine Hospital at Gangdong) , Yoon, Jin-Young (Department of Acupuncture and Moxibustion, Kyung Hee University Korean Medicine Hospital at Gangdong) , Lee, Chang Hee (Department of Acupuncture and Moxibustion, Kyung Hee University Korean Medicine Hospital at Gangdong) , Shim, Sung-Eun (Department of Acupuncture and Moxibustion, Kyung Hee University Korean Medicine Hospital at Gangdong) , Kim, Jeong Hyon (Department of Acupuncture and Moxibustion, Kyung Hee University Korean Medicine Hospital at Gangdong) , Goo, Bon Hyuk (Department of Acupuncture and Moxibustion, Kyung Hee University Korean Medicine Hospital at Gangdong) , Park, Yeon-Cheol (Department of Acupuncture and Moxibustion, Kyung Hee University Korean Medicine Hospital at Gangdong) , Seo, Byung-Kwan (Department of Acupuncture and Moxibustion, Kyung Hee University Korean Medicine Hospital at Gangdong) , Nam, Sang-soo (Department of Acupuncture and Moxibustion, Kyung Hee University Korean Me) , Baek, Yong-Hyeon

Abstract ▼ AI-Helper

The objective of this study was to review clinical trials of pharmacopuncture treatment for Frozen Shoulder and to evaluate trends in this field. The literature search was performed using PubMed, the Cochrane Library, China National Knowledge Infrastructure, and 5 Korean electronic databases. A combination of "pharmacopuncture," "acupoint injection," "Frozen Shoulder," "adhesive capsulitis," and "periarthritis of shoulder" search terms were used. A total of 9 studies were included in this review. The studies were classified into herbal extract-based (5 types) and animal-based (2 types) pharmacopuncture treatment of Frozen Shoulder. There were 14 different acupoints and Ashi points used in the 9 studies. The total volume of herbal extract-based pharmacopuncture injected was usually between 2 mL and 4 mL, and for animal-based pharmacopuncture it was 1 ml. In most studies of Frozen Shoulder, pain was reduced and function was significantly improved after pharmacopuncture treatment. These results demonstrate that pharmacopuncture alleviates pain and restores function in patients with Frozen Shoulder. Further studies must be conducted on pharmacopuncture for management of Frozen Shoulder.

주제어

AI 본문요약
AI-Helper

* AI 자동 식별 결과로 적합하지 않은 문장이 있을 수 있으니, 이용에 유의하시기 바랍니다.

문제 정의

However, a review of pharmacopuncture for the management of Frozen Shoulder has not been reported. Therefore, this review was conducted to collate clinical evidence and suggest a direction for future research.

제안 방법

Articles selected for inclusion in this review included studies on the treatment of Frozen Shoulder that used (1) pharmacopuncture or acupoint injection, and (2) clinical trials including randomized controlled trials (RCTs) and non-RCTs. Full text articles that met the inclusion criteria were retrieved and read carefully.
The studies included in this review used animal-based and herbal extract-based pharmacopuncture. In the animal-based pharmacopuncture study that used BV [9], the injection was prepared from dried honey BV by diluting the powder with saline solution.
The study design data were extracted and classified using a predefined data extraction form that designated the type of participants, the intervention (materials of pharmacopuncture and injection method), and the outcome measures.

대상 데이터

Fourteen acupoints (LI15, TE14, SI9, SI11, GB21, LI14, LI11, LI16, SI12, SI14, SI15, LU5, Jianneiling and Jianhou) and Ashi point were used in the studies reviewed. The most common acupoint used was LI15, which was used in 6 studies.
Among herbal extract-based injections, Ligusticum chuanxiong Hort, Angelica sinensis, and Salvia miltiorrhiza were the most frequently used herbal ingredients for pharmacopuncture. Fourteen kinds of acupoints and Ashi point were used in the studies, the most common acupoints used were LI15, TE14, SI9, SI11, GB21, LI14, and Jianneiling. The total volume of herbal extracts injected was approximately 2-4 mL and for animal-based pharmacopuncture it was 1 mL.
The commonly used acupoints in the studies included in this review were LI15, TE14, SI9, SI11, GB21, LI14 and Jianneiling. A previous review article reported that LI15, TE14, and LI14 acupoints were frequently used to treat Frozen Shoulder [8].
The search initially generated 379 articles out of which duplicates were eliminated. In the next step, the titles and abstracts of the articles were examined, and those that were not related to the topic of interest were removed.

성능/효과

There were 5 types of herbal extract-based pharmacopuncture that was used in the included studies. There was YTS, which is an injectable solution composed of the herb pair of Asarum sieboldii, Angelica sinensis, Ligusticum chuanxiong Hort, Notopterygium incisum, Angelica pubescens Radix, Saposhnikoviae Radix, and Angelica dahurica. In 2 studies that used YTS injection, improvement were observed in symptoms and physical scores [15,16], and the treatment was reported to have an analgesic and an anti-inflammatory effect on Frozen Shoulder [17].

후속연구

However, owing to the small number of studies included in the review, only a qualitative analysis of the data could be performed. Further studies must be carried out to provide additional evidence to support these findings.
Although several studies of Korean pharmacopuncture have been published, adequate literature reviews of these studies for specific conditions such as a treatment for Frozen Shoulder have not been performed. Therefore, the purpose of this study was to perform a literature review to report clinical evidence for the use of pharmacopuncture for the management of Frozen Shoulder, and suggest a direction for future research in this field.

참고문헌 (31)

Zreik NH, Malik RA, Charalambous CP. Adhesive capsulitis of the shoulder and diabetes: a meta-analysis of prevalence. Muscles Ligaments Tendons J 2016;6:26-34.
Wong CK, Levine WN, Deo K, Kesting RS, Mercer EA, Schram GA et al. Natural history of frozen shoulder: fact or fiction? A systematic review. Physiotherapy 2017;103:40-47.

상세보기
Maund E, Craig D, Suekarran S, Neilson A, Wright K, Brealey S et al. Management of frozen shoulder: a systematic review and cost-effectiveness analysis. Health Technol Assess 2012;16:1-264.
Lee KH, Cho YY, Kim SC, Sun SH. Histor y of research on pharmacopuncture in Korea. J Pharmacopunct 2016;19:101-108.

원문보기 상세보기
Lim CS, Park SK, Sun SH, Lee KH. Research on Korean Pharmacopuncture in South Korea since 2007. J Pharmacopuncture 2014;17:15-21.

원문보기 상세보기
Hand C, Clipsham K, Rees JL, Carr AJ. Long-term outcome of frozen shoulder. J Shoulder Elbow Surg 2008;17:231-236.

상세보기
Shaffer B, Tibone JE, Kerlan RK. Frozen shoulder; A long-term follow-up. J Bone Joint Surg Am 1992;74:738-746.

상세보기
Adam SM, Prescott DE. Is acupuncture an effective treatment to improve range of motion and pain in frozen shoulder contracture syndrome? A narrative review. Acupunct Physiother 2016;28:1-17.
Koh PS, Seo BK, Cho NS, Park HS, Park DH, Baek YH et al. Clinical effectiveness of bee venom acupuncture and physiotherapy in the treatment of adhesive capsulitis: a randomized controlled trial. J Shoulder Elbow Surg 2013;22:1053-1062.

상세보기
Koburova KL, Michailova SG, Shkenderov SV. Further investigation on the anti-inflammatory properties of adolapin-bee venom polypeptide. Acta Physiol Pharmacol Bulg 1985;11:50-55.

상세보기
Park HJ, Lee SH, Son DJ, Oh KW, Kim KH, Song HS et al. Anti-arthritic effect of bee venom: inhibition of inflammation mediator generation by suppression of NF-kappaB through interaction with the p50 subunit. Arthritis Rheum 2004;50:3504-3515.

상세보기
Park HJ, Son DJ, Lee CW, Choi MS, Lee US, Song HS et al. Mellitin inhibits inflammatory target gene expression and mediator generation via interaction with IkappaB kinase. Biochem Pharmacol 2007;73:237-247.

상세보기
Kim DH, Kim HY, Lee GH, Lee GM. Ef fect of Scolopendrid Pharmacopuncture Therapy on Frozen Shoulder Patients. J Korean Acupunct Moxib Soc 2009; 26: 1-14. [in Korean].
Kim SN, Kim SC, Choi HG, Soh KS, Lim JA, Hwang WJ et al. Inhibitory Effect of Scolopendrid Aqua-Acupuncture Injected at Hwando (GB30) on Neuropathic Pain in Rats. J Korean Acupunct Moxib Soc 2004;21:145-167. [in Korean].
Li L. Clinical Effect of Acupuncture Injection with Yi-tong-shu Injection and Functional Exercise on Periarthritis of Shoulder. Chin Foreign Med Res 2015;23:127-128. [in Chinese].
Qian WZ, Liu YS, Guo L, Zhou Y, Ma SZ, Yan BJ et al. Clinical Observation of Acupoint Injection combined with Functional Exercise for Scapulohumeral Periarthritis. J Emerg Tradit Chin Med 2012;21:1042-1043. [in Chinese].
Liu J, Wu XJ, Chen LM, Cao LQ, He JY. Analgesic and anti-inflammatory effects of Yitongshu injection. Northwes Pharmaceu J 2004;3:113. [in Chinese].
Xu BG, Wang J, Dai LJ. Danxiang injection acupoint injection for treatment of moderate and severe scapulohumeral periarthritis. Chin J Rehab 2011;26:430-431. [In Chinese]
Qi CM, Zhao YX, Li J, Chen QG. Clinical Observation of Fufang-Danggui Injection Combined with Rehabilitation Training for Treatment of Periarthritis of Shoulder. Chin J Ethnomed Ethnophar 2012;23:91. [in Chinese].
Liu Y. Clinical Observation of Acupoint Injection for Periarthritis of Shoulder in 40 cases. Guide J Tradit Chin Med 2008;14:58. [in Chinese].
Chen Z. Therapeutic effect of Fufang-Dangguiacupoint injection combined with combined with functional exercise on the treatment of frozen shoulder. Nei Mongol J Tradit Chin Med 2015;5:93. [in Chinese].
Chen F, Yan ZK, Yang B. Effects of acupoint-injection of compound Angelica-root Injectio on cerebral Bcl-2 and Bax immunoactivity and hemorheology in rats with cerebral ischemia-reperfusion injury. Acupunct Res 2011;36:85-89. [in Chinese].
Feng MZ, Chen SL. Treatment of 26 cases of adhesive scapulohumeral periarthritis with Zhengqing-Fengtongning acupoint injection combined with Danshen-Chuanxiong acuopoint injection. Guide J Tradit Chin Med 2017;23:98-100. [in Chinese].
Zhang X, Xu X, Litscher G, Sheng Z, Wang L, Litscher D et al. Study of Guanxinning Injection on Regulatory Mechanism of Bcl-2 and Bax by Liquid Nitrogen Freezing-Mediated Femoral Head Necrosis. Evid Based Complement Alternat Med 2017;2017:4540124.

상세보기
Gao B, Wu Y, Yang YJ, Li WZ, Dong K, Zhou J et al. Sinomenine exerts anticonvulsant profile and neuroprotective activity in pentylenetetrazole kindled rats: involvement of inhibition of NLRP1 inflammasome. J Neuroinflamm 2018;15:152.

상세보기
Liu L, Ning ZQ, Shan S, Zhang K, Deng T, Lu XP et al. Phthalide Lactones from Ligusticum chuanxiong inhibit lipopolysaccharide-induced TNFalpha production and TNF-alpha-mediated NF-kappaB Activation. Planta Med 2005;71:808-813.

상세보기
Yuan JF, Zhang ZQ, Fan ZC. Antioxidant effects and cytotoxicity of three purified polysaccharides from Ligusticumchuanxiong Hort. Carbohydr Polym 2008;74:822-827.

상세보기
Yang WJ, Li YR, Gao H, Wu XY, Wang XL, Wang XN et al. Protective effect of the ethanol extract from Ligusticumchuanxiong rhizome against streptozotocin-induced diabetic nephropathy in mice. J Ethnopharmacol 2018;227:166-175.

상세보기
Lee WS, Lim JH, Sung MS, Lee EG, Oh YJ, Yoo WH et al. Ethyl acetate fraction from Angelica sinensis inhibits IL- $1{\beta}$ -induced rheumatoid synovial fibroblast proliferation and COX-2, PGE2, and MMPs production. Biol Res 2014;47:41.

상세보기
Liu QS, Luo XY, Jiang H, Xing Y, Yang MH, Yuan GH et al. Salvia miltiorrhiza injection restores apoptosis of fibroblast-like synoviocytes cultured with serum from patients with rheumatoid arthritis. Mol Med Rep 2015;11:1476-1482.

상세보기
Jiang WY, Jeon BH, Kim YC, Lee SH, Sohn DH, Seo GS et al. PF2401-SF, standardized fraction of Salvia miltiorrhiza shows anti-inflammatory activity in macrophages and acute arthritis in vivo. Int Immunopharmacol 2013;16:160-164.

상세보기

표제어: PCR

동의어: Packet Collision Rate

용어 설명 출처 목록 (6)

용어 설명: PCR은 세균 특이성이 있는 primer를 이용하여 적은 수의 세균이 있을지라도 쉽게 검출할 수 있는 유용한 방법이며, 이를 이용하여 구강 내 치면세균막이나 타액에서 직접 세균을 검출할 수 있게 되었다[8].

내보내기 구분	파일저장 인쇄 메일전송
구성항목	기본정보 상세정보 관리번호, 논문명, 저널/프로시딩명, 저자 , 발행년, 권, 호, 시작페이지, 끝페이지, 발행기관 관리번호, 논문명, 대등논문명, 저자 , 저널/프로시딩명, 발행기관, 발행년, 발행언어, 권, 호, 시작페이지, 끝페이지, ISBN, ISSN, 주제분야, 키워드, 초록(한글), 초록(영문), 저자(소속기관)
저장형식	Text(ASCII format) Excel format RefWorks Direct Export RIS format (for Reference Manager, ProCite, EndNote), Scholar's Aids, Mendeley
메일정보	받는사람 (필수) @ 보내는사람 (선택) @ 제목 내용 KISTI 검색결과 이메일 서비스
안내	총 건의 자료가 검색되었습니다. 다운받으실 자료의 인덱스를 입력하세요. (1-10,000) 검색결과의 순서대로 최대 10,000건 까지 다운로드가 가능합니다. 데이타가 많을 경우 속도가 느려질 수 있습니다.(최대 2~3분 소요) 다운로드 파일은 UTF-8 형태로 저장됩니다. 파일의 내용이 제대로 보이지 않을실 때는 웹브라우저 상단의 보기 -> 인코딩 -> 자동선택 여부를 확인하십시오. ~ Text(ASCII format) Excel format

연합인증