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Anti-Inflammatory Role of TAM Family of Receptor Tyrosine Kinases Via Modulating Macrophage Function 원문보기

Molecules and cells, v.42 no.1, 2019년, pp.1 - 7  

Lee, Chang-Hee (Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University) ,  Chun, Taehoon (Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University)

Abstract AI-Helper 아이콘AI-Helper

Macrophage is an important innate immune cell that not only initiates inflammatory responses, but also functions in tissue repair and anti-inflammatory responses. Regulating macrophage activity is thus critical to maintain immune homeostasis. Tyro3, Axl, and Mer are integral membrane proteins that c...

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가설 설정

  • Pleotropic inhibition of inflammatory responses by TAM family receptors expressed on macrophages. (A) TAM receptor signaling enhances phagocytosis of apoptotic cells. (B) Attenuation of type I IFN-mediated inflammatory responses by TAM receptor signaling.
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참고문헌 (64)

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