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NTIS 바로가기Journal of Korean Medicine Rehabilitation : JKMR = 한방재활의학과학회지, v.29 no.4, 2019년, pp.1 - 14
Objectives The object of this study was to assess the effect of Gyejibokryunghwan (GBH) on anti-oxidant and anti-inflammatory activities in RAW 264.7 cells and on factors associated with fracture union in tibia-fractured rats. Methods The 1,1-diphenyl-2-picryl-hydrazyl (DPPH) radical scavenging acti...
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핵심어 | 질문 | 논문에서 추출한 답변 |
---|---|---|
골절은 무엇인가? | 골절은 뼈에 가해지는 과도한 힘으로 인하여 뼈의 연속성이 일부 혹은 전체에서 상실된 것을 말하며 대개 주위의 연부조직 손상을 동반한다1). 골절이 발생하면 보통 통증과 압통, 종창, 기능장애 등의 국소증상이 나타나며 심할 경우 호흡곤란, 쇼크 등의 전신증상이 나 타날 수 있다2). | |
골절이 동반하는 증상은 무엇이 있는가? | 골절은 뼈에 가해지는 과도한 힘으로 인하여 뼈의 연속성이 일부 혹은 전체에서 상실된 것을 말하며 대개 주위의 연부조직 손상을 동반한다1). 골절이 발생하면 보통 통증과 압통, 종창, 기능장애 등의 국소증상이 나타나며 심할 경우 호흡곤란, 쇼크 등의 전신증상이 나 타날 수 있다2). | |
골절의 치유 과정은 어떤 단계들을 거쳐 이루어지는가? | 골절의 치유 과정은 조직학적으로 편의상 세 단계로 나뉘는데 이는 염증기, 복원기, 재형성기이다1). 염증기 는 골절이 발생한 직후부터 시작되는데 연관된 혈관이 파열되고 혈종이 발생하면서 염증세포 및 섬유세포가 동원된다19). 이어서 혈소판과 염증세포는 염증성 cytokine 을 분비하고, 혈종은 점차 육아 조직으로 대치된다19). 섬유모세포는 새로운 기질을 만들기 시작하고 파골세포가 출현하기 시작하여 골흡수를 시작한다1). 복원기에는 조골세포, 연골모세포 등의 세포들이 증식되면서 혈종이 있던 부위에는 섬유성 조직과 초자연골 및 미성숙 골로 이루어진 가골이 형성된다3). 이어서 섬유성 조직과 초자연골도 미성숙 골로 치환된다3). 재형성기에는 불필요하고 과잉 형성된 가골이 파골세포에 의해 흡수 되고 조골세포에 의해 성숙한 골이 만들어지면서 골절 이 임상적 그리고 방사선적으로 유합되어 모든 골의 상태가 정상으로 되돌아간다3). |
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