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NTIS 바로가기韓方眼耳鼻咽喉皮膚科學會誌 = The journal of Korean Medicine Ophthalmology & Otolaryngology & Dermatology, v.32 no.4, 2019년, pp.62 - 89
조효림 (동국대학교 분당한방병원 침구과) , 오세희 (동국대학교 일산한방병원 한방안이비인후피부과) , 김선혜 (동국대학교 분당한방병원 침구과) , 성원석 (동국대학교 분당한방병원 침구과) , 홍승욱 (동국대학교 일산한방병원 한방안이비인후피부과) , 김은정 (동국대학교 분당한방병원 침구과)
Objectives : The purpose of this study is to evaluate the effectiveness and safety of topical nasal application of Herbal medicine compared with Western medicine in the treatment of Allergic Rhinitis(AR). Methods : Electronic databases including Cochrane library, PubMed, EMBASE, CNKI, KMBASE, KISS, ...
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핵심어 | 질문 | 논문에서 추출한 답변 |
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알레르기성 비염이란 무엇인가? | 알레르기성 비염은 특징적인 알레르기 항원에 대한 IgE 매개 면역반응으로 염증이 발생하며, 주 증상은 수양성 비루, 코막힘, 재채기 및 가려움증으로, 이러한 증상 중 하나 또는 여러 가지의 증상이 복합된 질환이다1).선진국과 마찬가지로 알레르기성 비염은 우리나라의 알레르기 질환 중에서 가장 높은 비율을 차지하고 있고2-4), 유병률 또한 매년 증가하고 있으며, 알레르기성 비염으로 인한 증상은 삶의 질을 저해하며, 국내뿐 아니라 전 세계적으로 사회적, 경제적 부담을 주고 있다5,6). | |
서양의학에서 사용하는 알레르기성 비염 치료법들의 문제점은 무엇인가? | 서양의학에서는 알레르기성 비염의 치료로 회피요법, 약물치료 등을 사용하고 있는데, 이 중 회피요법은 가장 안전한 치료법이지만 만족할 만한 치료결과를 얻기는 역부족이며, 약물 치료 또한 두통, 어지럼증, 진전, 불면증 등의 원치 않는 부작용을 일으킬 수 있다. 알레르기 비염의 진단과 치료 가이드라인에 따르면, 면역치료법의 사용에 대한 권고가 증가하고 있으나7), 이 또한 부작용과 위험이 있어 사용에 주의가 필요하다. | |
중등증-중증 알레르기비염 치료의 1차 선택 약제로 국소용 스테로이드를 사용하는 이유는 무엇인가? | 현재 알레르기비염의 증상을 개선하는데 가장 효과적인 약제로 국소용 스테로이드를 선택하고 있으며, 중등증-중증 알레르기비염 치료의 1차 선택 약제로 인정되고 있다54). 비강 내 스테로이드 사용은 코점막과 상피세포 내 호산구, 호염기구, 비만세포 수를 감소시키고 전달물질(mediator) 방출을 차단하며, 호중구의 주화성(chemotaxis)를 억제하여 염증을 경감시켜 비염의 모든 증상을 완화시킨다. 하지만 장시간 사용 시 비중격에 약물 축적되어 궤양이 생기거나 비중격 천공의 발생 등의 위험이 증가하는 것으로 알려져 있다54). |
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