[논문]Molecular Mechanisms of Succinate Dehydrogenase Inhibitor Resistance in Phytopathogenic Fungi

Sang, Hyunkyu; Lee, Hyang Burm

doi:10.5423/rpd.2020.26.1.1

[국내논문] Molecular Mechanisms of Succinate Dehydrogenase Inhibitor Resistance in Phytopathogenic Fungi 원문보기

Research in plant disease = 식물병연구, v.26 no.1, 2020년, pp.1 - 7

Sang, Hyunkyu (Department of Integrative Food, Bioscience and Biotechnology, Chonnam National University) , Lee, Hyang Burm (Department of Agricultural Biological Chemistry, Chonnam National University)

Abstract ▼ AI-Helper

The succinate dehydrogenase inhibitor (SDHI) is a class of fungicides, which is widely and rapidly used to manage fungal pathogens in the agriculture field. Currently, fungicide resistance to SDHIs has been developed in many different plant pathogenic fungi, causing diseases on crops, fruits, vegetables, and turf. Understanding the molecular mechanisms of fungicide resistance is important for effective prevention and resistance management strategies. Two different mechanisms have currently been known in SDHI resistance. The SDHI target genes, SdhB, SdhC, and SdhD, mutation(s) confer resistance to SDHIs. In addition, overexpression of ABC transporters is involved in reduced sensitivity to SDHI fungicides. In this review, the current status of SDHI resistance mechanisms in phytopathogenic fungi is discussed.

Keyword

표/그림 (2)

그림 Fig. 1. Molecular mechanisms of succinate dehydrogenase inhibi-tor (SDHI) resistance in plant pathogenic fungi.
표 Table 1. SDHI resistance and molecular mechanisms reported in phytopathogenic fungi

AI 본문요약
AI-Helper

* AI 자동 식별 결과로 적합하지 않은 문장이 있을 수 있으니, 이용에 유의하시기 바랍니다.

문제 정의

Although the Fungicide Resistance Action Committee reports the status of SDHI resistance every year, the lists of reported fungal pathogens with SDHI resistance are not all included. This review describes the current knowledge of SDHI resistance and the resistance mechanisms in plant pathogenic fungi.

가설 설정

(A) Mutation(s) in the SdhB, SdhC, and SdhD results in a decreased in binding affinity for SDHI fungicides. (B) Overexpression of efflux transporters causes a reduced intracellular accumulation of SDHI fungicides. The illustration was created using a web app, BioRender (http:// www.

참고문헌 (47)

Amiri, A., Heath, S. M. and Peres, N. A. 2014. Resistance to fluopyram, fluxapyroxad, and penthiopyrad in Botrytis cinerea from strawberry. Plant Dis. 98: 532-539.

상세보기
Avenot, H., Sellam, A. and Michailides, T. 2009. Characterization of mutations in the membrane-anchored subunits AaSDHC and AaSDHD of succinate dehydrogenase from Alternaria alternata isolates conferring field resistance to the fungicide boscalid. Plant Pathol. 58: 1134-1143.

상세보기
Avenot, H. F., van den Biggelaar, H., Morgan, D. P., Moral, J., Joosten, M. and Michailides, T. J. 2014. Sensitivities of baseline isolates and boscalid-resistant mutants of Alternaria alternata from pistachio to fluopyram, penthiopyrad, and fluxapyroxad. Plant Dis. 98: 197-205.

상세보기
Avenot, H. F., Luna, M. and Michailides, T. J. 2019. Phenotypic and molecular characterization of resistance to the SDHI fungicide fluopyram in populations of Alternaria alternata from pistachio orchards in California. Crop Prot. 124: 104838.

상세보기
Avenot, H. F. and Michailides, T. J. 2007. Resistance to boscalid fungicide in Alternaria alternata isolates from pistachio in California. Plant Dis. 91: 1345-1350.

상세보기
Avenot, H. F. and Michailides, T. J. 2010. Progress in understanding molecular mechanisms and evolution of resistance to succinate dehydrogenase inhibiting (SDHI) fungicides in phytopathogenic fungi. Crop Prot. 29: 643-651.

상세보기
Avenot, H. F., Sellam, A., Karaoglanidis, G. and Michailides, T. J. 2008. Characterization of mutations in the iron-sulphur subunit of succinate dehydrogenase correlating with boscalid resistance in Alternaria alternata from California pistachio. Phytopathology 98: 736-742.

상세보기
Avenot, H. F., Thomas, A., Gitaitis, R. D., Langston, D. B. Jr. and Stevenson, K. L. 2012. Molecular characterization of boscalid- and penthiopyrad-resistant isolates of Didymella bryoniae and assessment of their sensitivity to fluopyram. Pest Manag. Sci. 68: 645-651.

상세보기
Bardas, G. A., Veloukas, T., Koutita, O. and Karaoglanidis, G. S. 2010. Multiple resistance of Botrytis cinerea from kiwifruit to SDHIs, QoIs and fungicides of other chemical groups. Pest Manag. Sci. 66: 967-973.

상세보기
Bauske, M. J. and Gudmestad, N. C. 2018. Parasitic fitness of fungicide-resistant and -sensitive isolates of Alternaria solani. Plant Dis. 102: 666-673.

상세보기
Bauske, M. J., Mallik, I., Yellareddygari, S. K. R and Gudmestad, N. C. 2018. Spatial and temporal distribution of mutations conferring QoI and SDHI resistance in Alternaria solani across the United States. Plant Dis. 102: 349-358.

상세보기
De Miccolis Angelini, R. M., Masiello, M., Rotolo, C., Pollastro, S. and Faretra, F. 2014. Molecular characterisation and detection of resistance to succinate dehydrogenase inhibitor fungicides in Botryotinia fuckeliana (Botrytis cinerea). Pest Manag. Sci. 70: 1884-1893.

상세보기
Eyal, Z., Scharen, A. L., Prescott, J. M., Van Ginkel, M. 1987. The Septoria Diseases of Wheat: Concepts and Methods of Disease Management. CIMMYT, Mexico. 51 pp.
Fairchild, K. L., Miles, T. D. and Wharton, P. S. 2013. Assessing fungicide resistance in populations of Alternaria in Idaho potato fields. Crop Prot. 49: 31-39.

상세보기
Fan, Z., Yang, J.-H., Fan, F., Luo, C.-X. and Schnabel, G. 2015. Fitness and competitive ability of Alternaria alternata field isolates with resistance to SDHI, QoI, and MBC fungicides. Plant Dis. 99: 1744-1750.

상세보기
Fernandez-Ortuno, D., Perez-Garcia, A., Chamorro, M., de la Pena, E., de Vicente, A. and Tores, J. A. 2017. Resistance to the SDHI fungicides boscalid, fluopyram, fluxapyroxad, and penthiopyrad in Botrytis cinerea from commercial strawberry fields in Spain. Plant Dis. 101: 1306-1313.

상세보기
Fungicide Resistance Action Committee. 2015. List of species of resistant to SDHIs. URL https://www.frac.info/docs/defaultsource/working-groups/sdhi-references/list-of-speciesresistant-to-sdhis-april-2015.pdf?sfvrsn2d144a9a_2 [26 March 2020].
Fungicide Resistance Action Committee. 2020. FRAC Code List 2020: fungal control agents sorted by cross resistance pattern and mode of action (including FRAC Code numbering). URL https://www.frac.info/docs/default-source/publications/fraccode-list/frac-code-list-2020-final.pdf?sfvrsn8301499a_2 [26 March 2020].
Grabke, A. and Stammler, G. 2015. A Botrytis cinerea population from a single strawberry field in Germany has a complex fungicide resistance pattern. Plant Dis. 99: 1078-1086.

상세보기
Gudmestad, N. C., Arabiat, S., Miller, J. S. and Pasche, J. S. 2013. Prevalence and impact of SDHI fungicide resistance in Alternaria solani. Plant Dis. 97: 952-960.

상세보기
Hu, M.-J., Fernandez-Ortuno, D. and Schnabel, G. 2016. Monitoring resistance to SDHI fungicides in Botrytis cinerea from strawberry fields. Plant Dis. 100: 959-965.

상세보기
Jarvis, W. R. 1977. Botryotinia and Botrytis Species: Taxonomy, Physiology and Pathogenicity. Monograph No. 15. Research Branch, Canada Department of Agriculture, Ottawa, Canada. 195 pp.
Kim, Y. K. and Xiao, C. L. 2010. Resistance to pyraclostrobin and boscalid in populations of Botrytis cinerea from stored apples in Washington State. Plant Dis. 94: 604-612.

상세보기
Kretschmer, M., Leroch, M., Mosbach, A., Walker, A. S., Fillinger, S., Mernke, D. et al. 2009. Fungicide-driven evolution and molecular basis of multidrug resistance in field populations of the grey mould fungus Botrytis cinerea. PLoS Pathog. 5: e1000696.

상세보기
Leroch, M., Kretschmer, M. and Hahn, M. 2011. Fungicide resistance phenotypes of Botrytis cinerea isolates from commercial vineyards in South West Germany. J. Phytopathol. 159: 63-65.

상세보기
Leroux, P., Gredt, M., Leroch, M. and Walker, A.-S. 2010. Exploring mechanisms of resistance to respiratory inhibitors in field strains of Botrytis cinerea, the causal agent of gray mold. Appl. Environ. Microbiol. 76: 6615-6630.

상세보기
Li, X., Fernandez-Ortuno, D., Chen, S., Grabke, A., Luo, C.-X., Bridges, W. C. et al. 2014. Location-specific fungicide resistance profiles and evidence for stepwise accumulation of resistance in Botrytis cinerea. Plant Dis. 98: 1066-1074.

상세보기
Mallik, I., Arabiat, S., Pasche, J. S., Bolton, M. D., Patel, J. S. and Gudmestad, N. C. 2014. Molecular characterization and detection of mutations associated with resistance to succinate dehydrogenase-inhibiting fungicides in Alternaria solani. Phytopathology 104: 40-49.

상세보기
Miles, T. D., Miles, L. A., Fairchild, K. L. and Wharton, P. S. 2014. Screening and characterization of resistance to succinate dehydrogenase inhibitors in Alternaria solani. Plant Pathol. 63: 155-164.

상세보기
Miyamoto, T., Ishii, H., Seko, T., Kobori, S. and Tomita, Y. 2009. Occurrence of Corynespora cassiicola isolates resistant to boscalid on cucumber in Ibaraki Prefecture, Japan. Plant Pathol. 58: 1144-1151.

상세보기
Miyamoto, T., Ishii, H., Stammler, G., Koch, A., Ogawara, T., Tomita, Y. et al. 2010a. Distribution and molecular characterization of Corynespora cassiicola isolates resistant to boscalid. Plant Pathol. 59: 873-881.

상세보기
Miyamoto, T., Ishii, H. and Tomita, Y. 2010b. Occurrence of boscalid resistance in cucumber powdery mildew in Japan and molecular characterization of the iron-sulfur protein of succinate dehydrogenase of the causal fungus. J. Gen. Plant Pathol. 76: 261-267.

상세보기
Outwater, C. A., Proffer, T. J., Rothwell, N. L., Peng, J. and Sundin, G. W. 2019. Boscalid resistance in Blumeriella jaapii: distribution, effect on field efficacy, and molecular characterization. Plant Dis. 103: 1112-1118.

상세보기
Popko, J. T. Jr., Ok, C.-H., Campbell-Nelson, K. and Jung, G. 2012. The association between in vitro propiconazole sensitivity and field efficacy of five New England Sclerotinia homoeocarpa populations. Plant Dis. 96: 552-561.

상세보기
Popko, J. T. Jr., Sang, H., Lee, J., Yamada, T., Hoshino, Y. and Jung, G. 2018. Resistance of Sclerotinia homoeocarpa field isolates to succinate dehydrogenase inhibitor fungicides. Plant Dis. 102: 2625-2631.

상세보기
Rehfus, A., Miessner, S., Achenbach, J., Strobel, D., Bryson, R. and Stammler, G. 2016. Emergence of succinate dehydrogenase inhibitor resistance of Pyrenophora teres in Europe. Pest Manag. Sci. 72: 1977-1988.

상세보기
Rehfus, A., Strobel, D., Bryson, R. and Stammler, G. 2018. Mutations in sdh genes in field isolates of Zymoseptoria tritici and impact on the sensitivity to various succinate dehydrogenase inhibitors. Plant Pathol. 67: 175-180.

상세보기
Samaras, A., Madesis, P. and Karaoglanidis, G. S. 2016. Detection of sdhB gene mutations in SDHI-resistant isolates of Botrytis cinerea using high resolution melting (HRM) analysis. Front. Microbiol. 7: 1815

상세보기
Sang, H., Hulvey, J. P., Green, R., Xu, H., Im, J., Chang, T. et al. 2018. A xenobiotic detoxification pathway through transcriptional regulation in filamentous fungi. mBio 9: e00457-18.
Sang, H., Hulvey, J., Popko, J. T. Jr. Lopes, J., Swaminathan, A., Chang, T. et al. 2015. A pleiotropic drug resistance transporter is involved in reduced sensitivity to multiple fungicide classes in Sclerotinia homoeocarpa (F.T. Bennett). Mol. Plant Pathol. 16: 251-261.

상세보기
Sierotzki, H. and Scalliet, G. 2013. A review of current knowledge of resistance aspects for the next-generation succinate dehydrogenase inhibitor fungicides. Phytopathology 103: 880-887.

상세보기
Veloukas, T., Leroch, M., Hahn, M. and Karaoglanidis, G. S. 2011. Detection and molecular characterization of boscalid-resistant Botrytis cinerea isolates from strawberry. Plant Dis. 95: 1302-1307.

상세보기
Veloukas, T., Markoglou, A. N. and Karaoglanidis, G. S. 2013. Differential effect of SdhB gene mutations on the sensitivity to SDHI fungicides in Botrytis cinerea. Plant Dis. 97: 118-122.

상세보기
Von Schmeling, B. and Kulka, M. 1966. Systemic fungicidal activity of 1,4-oxathiin derivatives. Science 152: 659-660.

상세보기
Yamashita, M. and Fraaije, B. 2018. Non-target site SDHI resistance is present as standing genetic variation in field populations of Zymoseptoria tritici. Pest Manag. Sci. 74: 672-681.

상세보기
Yang, J. H., Brannen, P. M. and Schnabel, G. 2015. Resistance in Alternaria alternata to SDHI fungicides causes rare disease outbreak in peach orchards. Plant Dis. 99: 65-70.

상세보기
Yin, Y. N., Kim, Y. K. and Xiao, C. L. 2011. Molecular characterization of boscalid resistance in field isolates of Botrytis cinerea from apple. Phytopathology 101: 986-995.

상세보기

활용도 분석정보

상세보기

다운로드

내보내기

활용도 Top5 논문

해당 논문의 주제분야에서 활용도가 높은 상위 5개 콘텐츠를 보여줍니다.
더보기 버튼을 클릭하시면 더 많은 관련자료를 살펴볼 수 있습니다.

표제어: PCR

동의어: Packet Collision Rate

용어 설명 출처 목록 (6)

용어 설명: PCR은 세균 특이성이 있는 primer를 이용하여 적은 수의 세균이 있을지라도 쉽게 검출할 수 있는 유용한 방법이며, 이를 이용하여 구강 내 치면세균막이나 타액에서 직접 세균을 검출할 수 있게 되었다[8].

내보내기 구분	파일저장 인쇄 메일전송
구성항목	기본정보 상세정보 관리번호, 논문명, 저널/프로시딩명, 저자 , 발행년, 권, 호, 시작페이지, 끝페이지, 발행기관 관리번호, 논문명, 대등논문명, 저자 , 저널/프로시딩명, 발행기관, 발행년, 발행언어, 권, 호, 시작페이지, 끝페이지, ISBN, ISSN, 주제분야, 키워드, 초록(한글), 초록(영문), 저자(소속기관)
저장형식	Text(ASCII format) Excel format RefWorks Direct Export RIS format (for Reference Manager, ProCite, EndNote), Scholar's Aids, Mendeley
메일정보	받는사람 (필수) @ 보내는사람 (선택) @ 제목 내용 KISTI 검색결과 이메일 서비스
안내	총 건의 자료가 검색되었습니다. 다운받으실 자료의 인덱스를 입력하세요. (1-10,000) 검색결과의 순서대로 최대 10,000건 까지 다운로드가 가능합니다. 데이타가 많을 경우 속도가 느려질 수 있습니다.(최대 2~3분 소요) 다운로드 파일은 UTF-8 형태로 저장됩니다. 파일의 내용이 제대로 보이지 않을실 때는 웹브라우저 상단의 보기 -> 인코딩 -> 자동선택 여부를 확인하십시오. ~ Text(ASCII format) Excel format

연합인증