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NTIS 바로가기Journal of Korean Medicine Rehabilitation : JKMR = 한방재활의학과학회지, v.30 no.4, 2020년, pp.1 - 16
신우석 (상지대학교 대학원) , (상지대학교 한의과대학 약리학교실) , 차윤엽 (상지대학교 부속 한방병원 한방재활의학과)
Objectives The main purpose of this study was to evaluate the bone healing effect of Pahyeolsandong-tang (PHT)(Poxiesanteng-tang) extract in tibia fracture-induced mice. Methods PHT was extracted using a solution of 35% ethanol in 60℃ for 8 hours. Mice were randomly divided into 4 groups (nor...
핵심어 | 질문 | 논문에서 추출한 답변 |
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골절이란 무엇인가? | 골절이란 뼈의 연속성이 완전하게 또는 불완전하게 소실된 상태를 말하며 골조직 뿐 아니라 피부, 피하조직, 근육, 혈관, 신경 등의 손상이 같이 나타날 수 있다1). 골절은 흔한 손상의 하나로 대개는 교통사고, 폭력, 낙상, 스포츠 손상과 같은 외상에 의해 발생하지만 골다공증과 같이 비외상성으로 발생하는 경우도 있다. | |
골절의 일반적인 증상은 무엇이 있는가? | 골절은 흔한 손상의 하나로 대개는 교통사고, 폭력, 낙상, 스포츠 손상과 같은 외상에 의해 발생하지만 골다공증과 같이 비외상성으로 발생하는 경우도 있다. 골절의 일반적인 증상으로는 통증 및 압통, 골절단의 출혈, 연부조직 손상 등으로 인한 부종, 각종 기능장애, 구조 변형, 신경과 혈관의 손상 등이 나타날 수 있다2). | |
골절의 치유과정으로 염증기, 복원기, 재형성기는 각각 어떤 특징을 가지는가? | 염증기에는 혈종(hematoma)이 형성되고, 염증반응이 일어나면서 골형성 및 신생 혈관 형성을 위한 연쇄 반응이 나타나기 시작한다28). 복원기에는 혈종의 기질화 (organization)가 나타나게 되며 골세포 및 가골 형성과 관련된 세포들의 증식과 분화가 나타난다29). 초기에 혈관이 없는 연성 가골(soft callus)이 형성되며, 점차 연성 가골에 신생 혈관이 형성되면서 연골내 골화 작용이 일어난다30). 이 시기를 거치면서 연성 가골은 경성 가골(hard callus)이 되고 조골세포가 작용하여 유골 및 직골 등이 만들어진다. 재형성기는 가골이 점차 무기화된 골 조직으로 바뀌고 골수강을 재형성하는 시기이다22). 파골세포에 의해 불필요한 가골 및 골조직 등이 흡수된 다음 조골세포에 의해 성숙한 층판골로 대치되어 막내 골화가 이루어지면서 골 유합을 이루게 된다29). |
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