[논문]주름 개선을 위한 침 연구의 현황분석

정현석; 김태준; 박지연

doi:10.14406/acu.2021.009

[국내논문] 주름 개선을 위한 침 연구의 현황분석
Recent Research Trends of Acupuncture for Wrinkle Treatment 원문보기

Korean journal of acupuncture, v.38 no.2, 2021년, pp.62 - 74

정현석 (대전대학교 한의과대학 한의학과) , 김태준 (대전대학교 한의과대학 한의학과) , 박지연 (대전대학교 한의과대학 한의학과)

Abstract ▼ AI-Helper

Objectives : The aim of this study is to analyze the effect of acupuncture and the details of acupuncture treatment methods on skin wrinkles. Methods : Search was conducted in Pubmed, KISS, and NDSL databases for acupuncture studies on skin wrinkles. The detailed therapeutic techniques of acupuncture used for skin wrinkles and the effect of acupuncture on skin wrinkle improvement were analyzed. Then, the study results using the same indicator were compared through meta-analysis in order to compare the effects of acupuncture with the control group. The quality of randomized controlled trials (RCTs) was assessed using the risk of bias (ROB) assessment tool (Ver. 1.0, Cochrane Collaboration). Results : A total of 10 RCTs and 19 case series were included in this study. The most frequently used therapeutic technique for skin wrinkle improvement was Microneedle therapy system (MTS, n=19), and they were mostly used with aesthetic solutions (13 out of 19 studies). Skin wrinkle related indexes were most commonly used to evaluate skin wrinkle improvement (n=14). Panax Ginseng pharmacopuncture showed the most remarkable effect in improving the range of skin wrinkles and the depth of skin wrinkles. MTS+epidermal growth factor improved the levels of skin hydration, skin elasticity, and variation of skin pigment the most. MTS+Endothelial precursor cell improved the number of skin melanin the most. Three RCTs included in the meta-analysis showed moderate ROB on average. Conclusions : Acupuncture treatment was effective in improving skin wrinkles. However, a precise study design using unified indicators and appropriate controls needs to be performed in further studies in order to establish more convincing evidence of the effectiveness of acupuncture for improving skin wrinkles.

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표/그림 (10)

그림 Fig. 1. Flow diagram for selection of studies.
표 Table 1. Treatment interventions and results on skin wrinkle in the included case series studies
표 Table 2. Acupuncture effects on wrinkles in the randomized controlled trials
그림 Fig. 2. A type of treatment technique used in acupuncture studies for wrinkles. (A) Treatment techniques used in acupuncture studies for wrinkles. (B) The type of Microneedle therapy system (MTS) used in acupuncture studies for wrinkles. (C) The type of loading fluid used in the loading patch. EA : Electroacpuncture, MFA : Miso facial acupuncture, PA : Pharmacopuncture, RFN : Radiofrquency acupuncture, RN : Roller needle, SN : Stamp needle, TEA : Thread embedding acupuncture, ULP : Unloading patch.
그림 Fig. 3. Frequency of effect index used in acupuncture studies for wrinkles. The 'skin wrinkle' item includes the range of wrinkles, number of wrinkles, and depth of wrinkles. The 'skin melanin' item includes the numerical value of melanin, the variation of pigment, and skin brightness.
그림 Fig. 4. Reduction ratio in the range of skin wrinkles and the depth of skin wrinkles. The degree of reduction after treatment compared to before treatment was expressed as a percentage. (A) Reduction ratio of each therapeutic skills in the range of skin wrinkles. The value of MFA was calculated as the average of 3 studies. (B) Reduction ratio of each therapeutic skills in the depth of skin wrinkles. AD : Adenosine, GA : Ginseng pharmacopuncture, MFA : Miso facial acupuncture, MTS : Microneedle therapy system, TEA : Thread embedding acupuncture.
그림 Fig. 5. Increase ratio in the skin hydration and the skin elasticity. The degree of increase after treatment compared to before treatment was expressed as a percentage. (A) Increase ratio of each therapeutic skills in the skin hydration. The value of MTS+LA was calculated as the average of 2 studies. (B) Increase ratio of each therapeutic skills in the skin elasticity. AD : Adenosine, EGF : Epidermal growth factor, HA : Hyalruronicacid, HO : Horse oil, LA : L-ascorbic acid, MFA : Miso facial acupuncture, MTS : Microneedle therapy system, TEA : Thread embedding acupuncture.
그림 Fig. 6. Reduction ratio of the numerical value of skin melanin and the variation of skin pigment. The degree of reduction after treatment compared to before treatment was expressed as a percentage. (A) Reduction ratio in the numerical value of skin melanin. (B) Reduction ratio in the variation of skin pigment. EGF : Epidermal growth factor, EPC : Endothelial precursor cell, HA : Hyalruronicacid polymer, LA : L-ascorbic acid, MFA : Miso facial acupuncture, MTS : Microneedle therapy system, PRP : Platelet-rich plasma, SN : Stamp needle.
그림 Fig. 7. The effect of acupuncture on skin wrinkles based on the skin melanin index. Three Randomized controlled trials measuring skin melanin using Mexameter were used in the metaanalysis.
그림 Fig. 8. Risk of Bias (ROB) graph. ROB was evaluated according to the guidelines from the Cochrane Handbook for Systematic Reviews of Interventions⁴³⁾.

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