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CMIT/MIT 함유 가습기 살균제 제품의 제조 및 판매기업 형사판결 1심 재판 판결문에 대한 과학적 고찰 (II) - 동물실험, 폐 손상 판정기준, 개인 인과
A Scientific Critique of a Korean Court's Acquittal for Involuntary Manslaughter Related to 5-chloro-2-methylisothiazol-3(2H)-one/2-methylisothiazol-3(2H)-one (CMIT/MIT), a Humidifier Disinfectant (HD) Part II: Animal experiments, criteria for HD lung injury, and causality on individual levels 원문보기

韓國環境保健學會誌 = Journal of environmental health sciences, v.47 no.3, 2021년, pp.193 - 204  

박동욱 (한국방송통신대학교 보건환경학과) ,  조경이 (서울대학교 보건대학원 환경보건학과) ,  김지원 (한국방송통신대학교 보건환경학과) ,  최상준 (가톨릭대학교 의과대학 예방의학교실) ,  이소연 (울산대학교 의과대학, 서울아산병원 소아청소년과, 가습기살균제보건센터) ,  전형배 (강원대학교 법학전문대학원) ,  박태현 (강원대학교 법학전문대학원)

Abstract AI-Helper 아이콘AI-Helper

Objectives: In January 2021, the former heads of the manufacturer SK Chemical and the vendor Aekyung were acquitted for manufacturing and selling humidifier disinfectant (HD) containing 5-chloro-2-methylisothiazol-3(2H)-one/2-methylisothiazol-3(2H)-one (CMIT/MIT). In this article, we analyzed the ra...

주제어

표/그림 (2)

참고문헌 (27)

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  6. The Cosmetic Ingredient Review (CIR). Amended Safety Assessment of Methylchloroisothiazolinone and Methylisothiazolinone as Used in Cosmetics. 2020. Available: https://online.personalcarecouncil.org/ctfa-static/online/lists/cir-pdfs/FR787.pdf [accessed in Jan, 2021]. 

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  15. ECHA. Committee for Risk Assessment RAC. Opinion proposing harmonised classification and labelling at EU level of Reaction mass of: 5-chloro2-methyl-4-isothiazolin-3-one [EC no. 247-500-7] and 2-methyl-2H-isothiazol-3-one [EC no. 220-239-6] (3:1); Reaction mass of: 5-chloro-2-methyl-4-isothiazolin-3-one [EC no. 247-500-7] and 2-methyl-4-isothiazolin-3-one [EC no. 220-239-6] (3:1): European Chemicals Agency, 2016. 

  16. Cho HJ, Lee SY, Park D, Ryu SH, Yoon J, Jung S, et al. Early-life exposure to humidifier disinfectant determines the prognosis of lung function in children. BMC Pulm Med. 2019; 19(1): 261. [published Online First: 2019/12/25] 

  17. Lee SY, Park DU, Do KH, Jang SJ and Hong SJ. The Pathological Findings of Chloromethylisothiazolinone and Methylisothiazolinone-associated Lung Injury. J Korean Med Sci. 2019; 34(14): e102. [published Online First: 2019/04/13] 

  18. Lee E, Son SK, Yoon J, Cho HJ, Yang SI, Jung S, et al. Two Cases of Chloromethylisothiazolinone and Methylisothiazolinone-associated Toxic Lung Injury. J Korean Med Sci. 2018; 33(16): e119. 

  19. Cho HJ, Park DU, Yoon J, Lee E, Yang SI, Kim YH, et al. Effects of a mixture of chloromethylisothiazolinone and methylisothiazolinone on peripheral airway dysfunction in children. PLOS ONE. 2017; 12(4): e0176083. 

  20. Park DU, Ryu SH, Lim HK, Kim SK, Choi YY, Ahn JJ, et al. Types of household humidifier disinfectant and associated risk of lung injury (HDLI) in South Korea. Science of The Total Environment. 2017; 596-597: 53-60. 

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  24. Ryu SH, Park DU, Lee E, Park S, Lee SY, Jung S, et al. Humidifier disinfectant and use characteristics associated with lung injury in Korea. Indoor Air. 2019; 29: 735-747. 

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  26. Park DU, Choi YY, Ahn JJ, Lim HK, Kim SK, Roh HS, et al. Relationship between Exposure to Household Humidifier Disinfectants and Risk of Lung Injury: A Family-Based Study. PLOS ONE. 2015; 10(5): e0124610. 

  27. Park DU, Park SK, Kim J, Park J, Ryu SH, Park JH, et al. Characteristics of Exposure to Chloromethylisothiazolinone (CMIT) and Methylisothiazolinone (MIT) among Humidifier Disinfectant-Associated Lung Injury (HDLI) Patients in South Korea. Molecules. 2020; 25(22): e5284. 

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