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인삼과 도라지의 약리적 효과와 약동학적 특성
Pharmacological Effects and Pharmacokinetic Properties of Panax ginseng and Platycodon grandiflorum 원문보기

Korean journal of crop science = 韓國作物學會誌, v.67 no.4, 2022년, pp.305 - 318  

정솔 (가톨릭관동대학교 의과대학 보건의료융합연구소) ,  안상준 (가톨릭관동대학교 의과대학 보건의료융합연구소) ,  김영인 (가톨릭관동대학교 의과대학 보건의료융합연구소) ,  주효진 (가톨릭관동대학교 의과대학 보건의료융합연구소) ,  이상엽 (가톨릭관동대학교 의과대학 보건의료융합연구소) ,  김두영 (가톨릭관동대학교 의과대학 보건의료융합연구소)

초록
AI-Helper 아이콘AI-Helper

본 총설은 인삼과 도라지의 노화와 관련된 건강효과에 대하여 주요 기능성물질의 약리적, 약동학적 효과에 대한 연구들을 조사하여 과학적 근거를 정리하였다. 도라지와 인삼의 주요 기능성물질은 사포닌이므로 유사한 분자구조로 공통적으로 항염증 및 항산화 효과, 신경 보호효과와 항암작용, 항대사증후군 효과(고혈압, 이상지질혈증, 당뇨, 비만의 개선)가 확인되었다. 도라지의 사포닌은 Platycodin으로 기관지에 관련한 효능이 주가 되었지만 그 외에도 사포닌이 가진 공통적인 건강에 긍정적인 효과에 대해서 검증이 되어 있었다. 도라지의 효능에 대한 연구는 주로 실험실 연구나 동물 실험이 많았고 사람에게 적용한 임상연구는 적은 편이었다. 한편 인삼의 사포닌은 Ginsenoside로 사포닌의 효능으로 잘 알려진 항염증, 항산화, 항암, 항대사증후군에 대한 효능에 대하여 많은 임상연구를 통하여 그 효능이 검증되어 있었다. 인삼과 도라지의 두 종류의 사포닌 모두 정제된 자체로는 체내 흡수율이 매우 낮았지만 추출이나 발효 등의 방법을 통하여 체내흡수율을 높이는 방법들이 연구되어 있었다.

Abstract AI-Helper 아이콘AI-Helper

To minimize the effects of aging-related comorbidities and to maintain a good quality of life and physical independence for a longer period, the improvement of lifestyle and dietary habits is essential, and healthy foods can be helpful. Among them, medicinal plant such as ginseng (Panax ginseng) and...

주제어

참고문헌 (116)

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