[논문]셀레늄의 2020 한국인 영양소 섭취기준 개정 및 권장식단의 셀레늄 함량 평가를 통한 식품의 셀레늄 데이터베이스 검토

최경숙; 이옥희

doi:10.4163/jnh.2022.55.4.430

셀레늄의 2020 한국인 영양소 섭취기준 개정 및 권장식단의 셀레늄 함량 평가를 통한 식품의 셀레늄 데이터베이스 검토
2020 Korean Dietary Reference Intakes of selenium and a review of selenium database of foods by evaluating of selenium contents of the recommended menus 원문보기

Journal of nutrition and health, v.55 no.4, 2022년, pp.430 - 440

초록
AI-Helper

셀레늄은 산화스트레스 방어 기능으로 인체의 면역기능 유지에 필수적 역할을 하고, 세포의 항산화기능, 면역기능, 갑상선호르몬 조절, 약물이나 중금속 위해에 대한 방어, 만성질환의 위험 감소에 필수 역할을 하는 미량무기질이다. 셀레늄 섭취의 부족은 암, 심혈관질환, 당뇨병, 신경질환, 골관절 및 근육괴사와 약화, 갑상선질환, 염증성 질환 등 다양한 만성적 질환의 위험을 높인다. 본 논문은 2020 한국인 영양소 섭취기준에서 셀레늄의 제정과 개정 근거 기준에 대해 설명하고, 셀레늄 데이터베이스의 현황과 향후 2025 한국인 영양소 섭취기준 설정을 위한 필요 연구에 대해 논의하였다. 셀레늄의 2020 한국인 영양소 섭취기준은 2015년에 이어 혈장 셀레노프로테인 P 수준이 최대가 되는 셀레늄의 평균필요량을 지표로 사용하였고, 중국인 대상의 보고치에 한국인의 기준체중과 변이계수를 적용하는 방법이 적용되었으며, 2015년에 비해 참고체중치의 변경에 따라 성별, 연령별 셀레늄 섭취기준에서 약간의 개정이 있었다. 향후 셀레늄 섭취기준 설정의 발전을 위해서는 1) 한국인 대상의 혈장 셀레노프로테인 P의 최대수준을 나타내는 셀레늄 섭취량을 파악하기 위한 셀레늄 중재연구가 필요하고, 2) 셀레늄 섭취량 판정의 정확성을 높이기 위한 영양평가 프로그램내 식품 셀레늄 데이터베이스의 검토와 식품의 셀레늄 함량 분석을 확대해야 하며, 3) 국민의 셀레늄 섭취와 체내 생물학적 지표와의 관계를 건강한 일반인뿐만 아니라 질환자 및 운동선수와 같은 특수 환경의 대상자들로 확대하는 연구가 요구된다.

Abstract ▼ AI-Helper

Selenium is an important trace mineral that plays an essential role in maintaining the body's immunity with oxidative stress defense and antioxidant activity, immunity, thyroid hormone control, defense against drug or heavy metal harm, and reducing the risk of chronic diseases. A selenium deficiency increases the risk of various chronic diseases, such as cancer, cardiovascular disease, diabetes, neurological disease, osteoarthritis, muscle necrosis and weakness, thyroid disease, and inflammatory diseases. This paper explains the criteria for establishing and revising selenium in the 2020 Dietary Reference Intake for Koreans (KDRIs) and reviews the current status of the selenium database and suggestions for setting the 2025 KDRIs in the future. In the 2020 KDRIs, the selenium intake with the maximum plasma selenoprotein P level was used as the criteria. The weight and coefficient of the variation were applied to the Chinese' reported values. Compared to 2015 KDRIs, there were some revisions in the selenium dietary reference intakes by gender and age according to the change in reference weight. To improve and revise selenium dietary reference intakes in the future, a selenium intervention study is needed to determine the maximum level of plasma selenoprotein P in Koreans. In addition, a revision of the selenium database of the nutritional assessment program (CAN-Pro 5.0) is needed. An analysis of the selenium content of foods should be expanded to assess the selenium intake accurately. In addition, research on the relationship between selenium intake and the biological indicators in the body is required for healthy people and subjects of special environments, such as patients and athletes with various oxidative stress.

주제어

표/그림 (2)

표 Table 1. 2015 and 2020 KDRIs: selenium
표 Table 2. Selenium contents of recommended menus of 2020 KDRIs

참고문헌 (45)

Sunde RA. Selenium. In: Ross AC, Caballero B, Cousins RJ, Tucker KL, Ziegler TR, editors. Modern Nutrition in Health and Disease. 11th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2012.
Sunde RA. Selenium. In: Coates PM, Betz JM, Blackman MR, Cragg GM, Levine M, Moss J, et al., editors. Encyclopedia of Dietary Supplements. 2nd ed. New York, NY: Informa Healthcare; 2010.
Choi YS, Hesketh JE. Nutritional biochemistry of selenium. J Korean Soc Food Sci Nutr 2006; 35(5): 661-670.

원문보기 상세보기
Lee O, Moon J, Chung Y. Assessment of selenium status in adult females according to life cycle. Korean J Nutr 2003; 36(5): 491-499.
Lee O, Moon J, Chung Y. The relationship between serum selenium levels and lipid profiles in adult women. J Nutr Sci Vitaminol (Tokyo) 2003; 49(6): 397-404.

상세보기
Lee YJ, Jeong EJ, Whang JA, Kim MK, Lee JH, Park TS, et al. A study on the serum concentration of antioxidant-related minerals in normal Koreans. Korean J Nutr 1998; 31(3): 324-332.
Kim KH, Lim HS. Dietary intakes, serum concentrations, and urinary excretions of Fe, Zn, Cu, Mn, Se, Mo, and Cr of Korean young adult women. Korean J Nutr 2006; 39(8): 762-772.
Lee O, Chung Y, Moon J. Iron status according to serum selenium concentration and physique in young female adults. Korean J Nutr 2010; 43(2): 114-122.
Ferreira RL, Sena-Evangelista KC, de Azevedo EP, Pinheiro FI, Cobucci RN, Pedrosa LF. Selenium in human health and gut microflora: bioavailability of selenocompounds and relationship with diseases. Front Nutr 2021; 8: 685317.

상세보기
Vinceti M, Dennert G, Crespi CM, Zwahlen M, Brinkman M, Zeegers MP, et al. Selenium for preventing cancer. Cochrane Database Syst Rev 2014; 2014(3): CD005195.

상세보기
Kohler LN, Florea A, Kelley CP, Chow S, Hsu P, Batai K, et al. Higher plasma selenium concentrations are associated with increased odds of prevalent type 2 diabetes. J Nutr 2018; 148(8): 1333-1340.

상세보기
Moghaddam A, Heller RA, Sun Q, Seelig J, Cherkezov A, Seibert L, et al. Selenium deficiency is associated with mortality risk from COVID-19. Nutrients 2020; 12(7): 2098.

상세보기
Zhang J, Taylor EW, Bennett K, Saad R, Rayman MP. Association between regional selenium status and reported outcome of COVID-19 cases in China. Am J Clin Nutr 2020; 111(6): 1297-1299.

상세보기
Alexander J, Tinkov A, Strand TA, Alehagen U, Skalny A, Aaseth J. Early nutritional interventions with zinc, selenium and vitamin D for raising anti-viral resistance against progressive COVID-19. Nutrients 2020; 12(8): 2358.

상세보기
Bae M, Kim H. The role of vitamin C, vitamin D, and selenium in immune system against COVID-19. Molecules 2020; 25(22): 5346.

상세보기
Kohler LN, Foote J, Kelley CP, Florea A, Shelly C, Chow HS, et al. Selenium and type 2 diabetes: systematic review. Nutrients 2018; 10(12): 1924.

상세보기
Lee OH. Assessment of selenium and zinc status in female collegiate athletes. J Nutr Health 2018; 51(2): 121-131.

원문보기 상세보기
Moon JH, Kim SH, Kim KS, Lee OH. INAA for the evaluation of selenium contents in grain foods consumed by Korean. J Radioanal Nucl Chem 2016; 309(1): 337-341.

상세보기
Berry MJ, Larsen PR. The role of selenium in thyroid hormone action. Endocr Rev 1992; 13(2): 207-219.

상세보기
Flohe L. Glutathione peroxidase. Basic Life Sci 1988; 49: 663-668.

상세보기
Brown KM, Arthur JR. Selenium, selenoproteins and human health: a review. Public Health Nutr 2001; 4(2B): 593-599.
Zachara BA. Mammalian selenoproteins. J Trace Elem Electrolytes Health Dis 1992; 6(3): 137-151.
Hill KE, Burk RF. Selenoprotein P: recent studies in rats and in humans. Biomed Environ Sci 1997; 10(2-3): 198-208.
Moghadaszadeh B, Beggs AH. Selenoproteins and their impact on human health through diverse physiological pathways. Physiology (Bethesda) 2006; 21(5): 307-315.

상세보기
Mo D. Pathology and selenium deficiency in Keshin-Beck disease. In: Combs GF, Spallholz JE Jr, Levander OA, Oldfield JE, editors. Selenium in Biology and Medicine. New York, NY: Van Nostrand Reinhold; 1987.
Jablonska E, Gromadzinska J, Sobala W, Reszka E, Wasowicz W. Lung cancer risk associated with selenium status is modified in smoking individuals by Sep15 polymorphism. Eur J Nutr 2008; 47(1): 47-54.

상세보기
Rayman MP. Selenium in cancer prevention: a review of the evidence and mechanism of action. Proc Nutr Soc 2005; 64(4): 527-542.

상세보기
Duffield-Lillico AJ, Dalkin BL, Reid ME, Turnbull BW, Slate EH, Jacobs ET, et al. Selenium supplementation, baseline plasma selenium status and incidence of prostate cancer: an analysis of the complete treatment period of the Nutritional Prevention of Cancer Trial. BJU Int 2003; 91(7): 608-612.

상세보기
Yang GQ, Xia YM. Studies on human dietary requirements and safe range of dietary intakes of selenium in China and their application in the prevention of related endemic diseases. Biomed Environ Sci 1995; 8(3): 187-201.

상세보기
Lippman SM, Klein EA, Goodman PJ, Lucia MS, Thompson IM, Ford LG, et al. Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the Selenium and Vitamin E Cancer Prevention Trial (SELECT). JAMA 2009; 301(1): 39-51.

상세보기
Peters U, Foster CB, Chatterjee N, Schatzkin A, Reding D, Andriole GL, et al. Serum selenium and risk of prostate cancer-a nested case-control study. Am J Clin Nutr 2007; 85(1): 209-217.

상세보기
Xia Y, Hill KE, Li P, Xu J, Zhou D, Motley AK, et al. Optimization of selenoprotein P and other plasma selenium biomarkers for the assessment of the selenium nutritional requirement: a placebo-controlled, double-blind study of selenomethionine supplementation in selenium-deficient Chinese subjects. Am J Clin Nutr 2010; 92(3): 525-531.

상세보기
Korean Nutrition Society. Korean Recommended Dietary Allowances. Seoul: Korean Nutrition Society; 2015.
Korean Nutrition Society. 2020 Dietary Reference Intakes for Koreans. Seoul: Korean Nutrition Society; 2020.
Yang HR. Study on the contents of selenium and zinc in human milk. Korean J Nutr 1995; 28(9): 872-879.
Moon SJ, Kang JS, Lee MJ, Lee JH, Ahn HS. A longitudinal study of micro-mineral concentrations in human milk. Korean J Nutr 1995; 28(7): 620-628.
Schroeder HA, Frost DV, Balassa JJ. Essential trace metals in man: selenium. J Chronic Dis 1970; 23(4): 227-243.

상세보기
Oh SH, Jo UY. Distribution of selenium content among Korean and Korean foods. Korean J Nutr 1983; 16(3): 185-192.
Yang HR. Study of the dietary selenium intake and selenium status of Korean women [dissertation]. Seoul: Dankook University; 2003.
Yang G, Yin S, Zhou R, Gu L, Yan B, Liu Y, et al. Studies of safe maximal daily dietary Se-intake in a seleniferous area in China. Part II: relation between Se-intake and the manifestation of clinical signs and certain biochemical alterations in blood and urine. J Trace Elem Electrolytes Health Dis 1989; 3(3): 123-130.
Kwak EH, Lee SL, Yoon JS, Lee HS, Kwon CS, Kwun IS. Macronutrient, mineral and vitamin intakes in elderly people in rural area of north Kyungpook province in South Korea. Korean J Nutr 2003; 36(10): 1052-1060.
Moon JH, Kim SH, Chung YS, Lee O. Application of instrumental neutron activation analysis to assess dietary intake of selenium in Korean adults from meat and eggs. J Radioanal Nucl Chem 2015; 303(2): 1561-1564.

상세보기
Willett W. Food and nutrients. In: Willet W, editor. Nutritional Epidemiology. New York, NY: Oxford University Press; 1990.
Korean Nutrition Society. 2020 Dietary Reference Intakes for Koreans: Application. Seoul: Korean Nutrition Society; 2022.
Korean Nutrition Society. Computer Aided Nutritional Analysis Program 5.0. Seoul: Korean Nutrition Society; 2022.

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