[논문]대뇌 신경 교종 18F-FDG PET/CT 검사에서 포도당 부하 기법에 대한 고찰

최용훈; 박민수; 임한상; 김재삼

대뇌 신경 교종 18F-FDG PET/CT 검사에서 포도당 부하 기법에 대한 고찰
A Discussion on Glucose Loading Method in 18F-FDG PET/CTfor Cerebral Gliomas 원문보기

핵의학기술 = The Korean journal of nuclear medicine technology, v.27 no.1, 2023년, pp.62 - 65

최용훈 (연세의료원 세브란스병원 핵의학과) , 박민수 (연세의료원 세브란스병원 핵의학과) , 임한상 (연세의료원 세브란스병원 핵의학과) , 김재삼 (연세의료원 세브란스병원 핵의학과)

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Purpose The purpose of this study is to determine whether the glucose loading method (GLM) is useful in the differentiation of cerebral gliomas by comparing it with fasting images. Materials and Methods The patients were 70 people diagnosed with cerebral gliomas, and the equipment was Discovery 710 (GE Healthcare, MI, USA). All patients fasted for more than 6 hours, and fasting images and GLM were performed under the same imaging conditions, and the examination interval was 1 to 14 days. GLM administered 250 ㎖ of 10% glucose solution prior to radiopharmaceutical injection. SUVmax of cerebral glioma and SUVmean of cerebral cortex were measured and then compared and analyzed by tumor-to-normal brain cortex ratio (TNR). Statistical analysis confirmed the difference between the two images with an independent-sample t-test. Results The averages of GLM and fasting TNR were 1.26 and 1.09, respectively, which were 15.6% higher in GLM. In low-grade, the difference in TNR was insignificant at 4%, but in high-grade, 23%, GLM was high. There was a statistically significant difference between the two images (P=0.008), but there was no statistically significant difference in TNR in the low grade (P=0.473), and there was a very significant difference in the high grade (P=0.005). Conclusion GLM increased TNR for cerebral gliomas. In particular, it was found that the TNR increased more in the high grade. Therefore, GLM is considered to be useful for the differentiation of high-grade gliomas.

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대뇌 신경 교종 18F-FDG PET/CT 검사에서 포도당 부하 기법에 대한 고찰
A Discussion on Glucose Loading Method in 18F-FDG PET/CTfor Cerebral Gliomas 원문보기

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대뇌 신경 교종 18F-FDG PET/CT 검사에서 포도당 부하 기법에 대한 고찰 A Discussion on Glucose Loading Method in 18F-FDG PET/CTfor Cerebral Gliomas 원문보기

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대뇌 신경 교종 18F-FDG PET/CT 검사에서 포도당 부하 기법에 대한 고찰
A Discussion on Glucose Loading Method in 18F-FDG PET/CTfor Cerebral Gliomas 원문보기