[논문]Histopathology of rabbit eyes with silicone-fluorosilicone copolymer oil as six months internal retinal tamponade

doi:10.1016/S0014-4835(05)80142-3

Histopathology of rabbit eyes with silicone-fluorosilicone copolymer oil as six months internal retinal tamponade

Experimental eye research, v.61 no.4, 1995년, pp.469 - 478

Doi, Motoaki (For correspondence at: The Schepens Eye Research Institute, 20 Staniford Street, Boston, MA 02114, U.S.A.) , Refojo, Miguel F.

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AbstractSilicone-fluorosilicone copolymer oil has low viscosity (175–185 cSt) and is heavier than water (density, 1·16 g cm−3). Short term retinal tolerance (within 2 months) of the silicone-fluorosilicone copolymer oil has been reported to be the same as that of currently used intraocular silicone oil. Ocular response of the purified silicone-fluorosilicone copolymer oil were examined clinically and histopathologically from 2·5 months to 6 months after vitreous cavity injection in rabbit phakic eyes, and compared the oil tolerance with that of purified silicone oil (0·97 g cm−3, 5000 cSt). The effects in anterior chamber also were examined within 4 weeks of the silicone-fluorosilicone copolymer oil injection in different rabbits. Silicone-fluorosilicone copolymer oil recovered from the vitreous cavity at 6 months was analysed for cholesterol and retinol content by high performance liquid chromatography.Because of its low viscosity, silicone-fluorosilicone copolymer oil was easy to inject and remove from the vitreous cavity with a 20-G needle. After the vitreous injection, discrete droplet formation by the silicone-fluorosilicone copolymer oil occurred more easily than by silicone oil. Medullary ray detachment was seen in a silicone oil-, and some silicone-fluorosilicone copolymer oil-injected eyes at 4–6 months. Histopathologically, after 3–6 months disappearance of outer plexiform layer and disorganization of the photoreceptor layer of silicone oil-, and silicone-fluorosilicone copolymer oil-injected eyes were seen in the superior and the inferior retina, respectively. Migration of the photoreceptor cell nuclei to the photoreceptor layer was found in the inferior retina of silicone-fluorosilicone copolymer oil-injected eyes at 5–6 months. Small droplets ingested by mononuclear cells were found in the vitreous cavity or preretina at 4–6 months in silicone-fluorosilicone copolymer oil-injected eyes. After the anterior chamber injection, silicone-fluorosilicone copolymer oil induced endothelial cell damage in the area where the oil contacted continuously. Retinol and cholesterol were identified in silicone-fluorosilicone copolymer oil removed from the vitreous cavity.Silicone-fluorosilicone copolymer oil may be useful as an intraoperative device in retinal detachment surgery and as a short term (up to about 2 months) retinal tamponade but we do not recommend it for long term retinal tamponade.

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참고문헌 (44)

Jpn. J. Ophthalmol. Ando 31 138 1987 Usefulness and limit of silicone in management of complicated retinal detachment
Invest. Ophthalmol. Vis. Sci. Araiz 34 522 1993 Antiproliferative effect of retinoic acid in intravitreous silicone oil in an animal model of proliferative vitreoretinopathy

상세보기
Retina Arroyo 13 245 1993 10.1097/00006982-199313030-00011 Silicone oil as a delivery vehicle for BCNU in rabbit proliferative vitreoretinopathy

상세보기
Am. J. Ophthalmol. Bornfeld 103 770 1987 10.1016/S0002-9394(14)74392-2 Ultrastructural characteristics of preretinal membranes from human eyes filled with silicone oil

상세보기
Br. J. Ophthalmol. Boulton 76 79 1992 10.1136/bjo.76.2.79 Biological activities of vitreous gel, retrohyaloid fluid and subretinal fluid from diabetic and non-diabetic eyes

상세보기
Am. J. Ophthalmol. Chang 106 668 1988 10.1016/0002-9394(88)90698-8 Intraoperative perfluorocarbon liquids in the management of proliferative vitreoretinopathy

상세보기
Retina Chang 11 367 1991 10.1097/00006982-199110000-00001 Experimental studies of tolerance to intravitreal perfluoro-n-octane liquid

상세보기
Am. J. Ophthalmol. Chang 103 29 1987 10.1016/S0002-9394(14)74165-0 Experimental vitreous replacement with perfluorotributylamine

상세보기
Arch. Ophthalmol. Crisp 105 546 1987 10.1001/archopht.1987.01060040116047 Effect of silicone oil viscosity on emulsification

상세보기
Retina De Molfetta 12 40 1992 10.1097/00006982-199212031-00009 The effect of simultaneous internal tamponade on fluid compartmentalization and its relationship to cell proliferation

상세보기
Exp. Eye Res. Doi 59 1994 10.1006/exer.1994.1160 Histopathology of rabbit eyes with intravitreous silicone-fluorosilicone copolymer oil

상세보기
Retina Eckardt 11 375 1991 10.1097/00006982-199110000-00002 Experimental intraocular tolerance to liquid perfluoro-octane and perfluoropolyether

상세보기
Graefes Arch. Clin. Exp. Ophthalmol. Gabel 225 160 1987 10.1007/BF02175441 Analysis of intraocularly applied silicone oils of various origins

상세보기
Arch. Ophthalmol. Gonvers 104 1057 1986 10.1001/archopht.1986.01050190115049 The effect of liquid silicone on the rabbit retina. Histologic and ultrastructural study

상세보기
Ophthalmologica Haut 191 150 1985 10.1159/000309578 Some of the most important properties of silicone oil to explain its action

상세보기
Hutton 166 1988 Proliferative Vitreoretinopathy (PVR) Silicone oil for management of PVR: complication of six-month and two-year results
Arch. Ophthalmol. Laroche 101 1422 1983 10.1001/archopht.1983.01040020424019 Ocular findings following intravitreal silicone injection

상세보기
Br. J. Ophthalmol. Lean 68 332 1984 10.1136/bjo.68.5.332 Experimental model of proliferative vitreoretinopathy (PVR) in the vitrectomized eye: effect of silicone oil

상세보기
Graefes Arch. Clin. Exp. Ophthalmol. Leaver 227 323 1989 10.1007/BF02169405 Vitrectomy and fluid/silicone-oil exchange for giant retinal tears: 5 years follow-up

상세보기
Ophthalmology Lewis 95 583 1988 10.1016/S0161-6420(88)33136-2 Perisilicone proliferation after vitrectomy for proliferative vitreoretinopathy

상세보기
Retina McCuen 5 198 1985 10.1097/00006982-198500540-00002 Silicone oil in vitreoretinal surgery. Part 2: results and complications

상세보기
Ophthalmic Res. Mester 18 81 1986 10.1159/000265419 Experimental studies with a high-density silicone oil for giant retinal tear
Arch. Ophthalmol. Miller 102 1708 1984 10.1001/archopht.1984.01040031392034 Intravitreal expanding gas bubble. A morphologic study in the rabbit eye

상세보기
Am. J. Ophthalmol. Miller 102 188 1986 10.1016/0002-9394(86)90143-1 Experimental epiretinal proliferation induced by intravitreal red blood cells

상세보기
Retina Miyamoto 4 264 1984 10.1097/00006982-198400440-00010 Perfluoroether liquid as a long-term vitreous substitute. An experimental study

상세보기
Arch. Ophthalmol. Miyamoto 104 1053 1986 10.1001/archopht.1986.01050190111048 Fluorinated oils as experimental vitreous substitutes

상세보기
Cornea Moreira 11 376 1992 10.1097/00003226-199209000-00003 Corneal toxicity study of two perfluorocarbon liquids in rabbit eyes

상세보기
Invest. Ophthalmol. Vis. Sci. Nakagawa 35 1923 1994 Antiproliferative effect of retinoic acid in silicone/fluorosilicone copolymer oil in a fibroblast platelet animal model of PVR
Invest. Ophthalmol. Vis. Sci. Nakamura 31 647 1990 Factors contributing to the emulsification of intraocular silicone and fluorosilicone oils
Invest. Ophthalmol. Vis. Sci. Nakamura 32 3007 1991 Ocular toxicity of low-molecular-weight components of silicone and fluorosilicone oils
Tissue Cell Nishizono 25 305 1993 10.1016/0040-8166(93)90028-J Evidence that Muller cells can phagocytize egg-lecithin-coated silicone particles

상세보기
Ophthalmology Norman 97 1671 1990 10.1016/S0161-6420(90)32374-6 Corneal endothelial permeability after anterior chamber silicone oil

상세보기
Retina Ober 3 77 1983 10.1097/00006982-198300320-00002 Experimental retinal tolerance to liquid silicone

상세보기
Retina Ohira 11 259 1991 10.1097/00006982-199111020-00012 Experimental retinal tolerance to emulsified silicone oil

상세보기
Polymeric Materials Science and Engineering Refojo 69 545 1993 Vitreous implants in retinal detachment surgery
Invest. Ophthalmol. Vis. Sci. Refojo 34 952 1993 Silicone-fluorosilicone copolymer oil for retinal tamponade in complicated retinal detachment surgery
Refojo 181 1988 Proliferative Vitreoretinopathy (PVR) Retinol and cholesterol in intraocular silicone and fluorosilicone oils
Ophthalmology Refojo 95 614 1988 10.1016/S0161-6420(88)33132-5 Extraction of retinol and cholesterol by intraocular silicone oils

상세보기
Sjostrand 449 1964 The rabbit in eye research The structure of the rabbit retina as revealed by electron microscopy
Retina Sparrow 13 56 1993 10.1097/00006982-199313010-00013 Retinal tolerance to intravitreal perfluoroethylcyclohexane liquid in the rabbit

상세보기
Jpn. J. Ophthalmol. Suzuki 35 282 1991 Effect of silicone oil on ocular tissues
Graefes Arch. Clin. Exp. Ophthalmol. Thresher 221 192 1984 10.1007/BF02134139 Gas-mediated vitreous compression: an experimental alternative to mechanized vitrectomy

상세보기
Invest. Ophthalmol. Vis. Sci. Tolentino 35 2070 1994 A new heavier than water liquid for posterior segment surgery
Invest. Ophthalmol. Vis. Sci. Yang 33 2436 1992 Quantitative assessment of growth stimulating activity of the vitreous during PVR

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Histopathology of rabbit eyes with silicone-fluorosilicone copolymer oil as six months internal retinal tamponade

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