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Experimental gerontology, v.35 no.9/10, 2000년, pp.1343 - 1352
Pericak-Vance, M.A. (Duke University Medical Center, Durham, North Carolina, USA) , Grubber, J. (Duke University Medical Center, Durham, North Carolina, USA) , Bailey, L.R. (Vanderbilt University Medical Center, Nashville, Tennessee, USA) , Hedges, D. (Duke University Medical Center, Durham, North Carolina, USA) , West, S. (Duke University Medical Center, Durham, North Carolina, USA) , Santoro, L. (Duke University Medical Center, Durham, North Carolina, USA) , Kemmerer, B. (Vanderbilt University Medical Center, Nashville, Tennessee, USA) , Hall, J.L. (Vanderbilt University Medical Center, Nashville, Tennessee, USA) , Saunders, A.M. (Duke University Medical Center, Durham, North Carolina, USA) , Roses, A.D. (GlaxoWellcome, Inc., Research Triangle Park, North Carolina, USA) , Small, G.W. (University of California at Los Angeles, Los Angeles, California, USA) , Scott, W.K. (Duke University Medical Center, Durham, North Carolina, USA) , Conneally, P.M. (Indiana University Medical Center, Indianapolis, Indiana, USA) , Vance, J.M. (Duke University Medical Center, Durham, North Carolina, USA) , Haines, J.L. (Vanderbilt University Medical Center, Nashville, Tennessee, USA)
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AbstractFour genes affecting Alzheimer's Disease (AD)(AP, PS1, PS2, and APOE) have been identified and a fifth potential gene localized to chromosome 12. Collectively, these genes explain at most half of the genetic effect in AD. Understanding the genetics of AD is critical to developing new treatme...
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