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Biochimica et biophysica acta. Gene structure and expression, v.1517 no.1, 2000년, pp.1 - 18
Jones, Nicholas A (School of Pharmaceutical Sciences, University of Nottingham, University Park, Nottingham NG7 2RD, UK) , Hill, I.R.C (School of Pharmaceutical Sciences, University of Nottingham, University Park, Nottingham NG7 2RD, UK) , Stolnik, Snjezana (School of Pharmaceutical Sciences, University of Nottingham, University Park, Nottingham NG7 2RD, UK) , Bignotti, Fabio (Dipartimento di Chimica e Fisica per L’) , Davis, Stanley S (Ingegneria e per i Materiali, Università) , Garnett, Martin C (di Brescia, via Valotti, 9-25133 Brescia, Italy)
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AbstractPolyplexes are now emerging as potentially useful vectors for gene therapy. To improve our understanding of how the chemical structure of the polymer affects the properties of these systems, a series of structurally related polymers, the linear poly(amidoamine)s (PAAs), have been examined fo...
Biochim. Biophys. Acta Schell 340 323 1974 10.1016/0005-2787(74)90277-9 Uptake of polynucleotised by mammalian cells XIV, stimulation of the uptake of polynucleotides by poly-L-lysine
Proc. Natl. Acad. Sci. USA Laemmli 72 4288 1975 10.1073/pnas.72.11.4288 Characterization of DNA condensates induced by poly(ethylene oxide) and polylysine
Crit. Rev. Ther. Drug Carrier Syst. Garnett 16 147 1999 10.1615/CritRevTherDrugCarrierSyst.v16.i2.10 Gene delivery systems using cationic polymers
Am. J. Med. Sci. Mack 307 138 1994 10.1097/00000441-199402000-00013 Cationic lipid enhances in vitro receptor-mediated transfection
Proc. Natl. Acad. Sci. USA Cotton 87 4033 1990 10.1073/pnas.87.11.4033 Transferrin-polycation-mediated introduction of DNA into human leukemic cells: stimulation by agents that affect the survival of transfected DNA or modulate transferrin receptor levels
Biochim. Biophys. Acta Erbacher 1324 27 1997 10.1016/S0005-2736(96)00204-0 The reduction of the positive charges of polylysine by partial gluconoylation increases the transfection efficiency of polylysine/DNA complexes
J. Mater. Sci. Mater. Med. Sgouras 1 61 1990 10.1007/BF00839070 Methods for the evaluation of biocompatibility of soluble synthetic polymers which have potential for biomedical use 1. Use of the tetrazolium-based colourimetic assay (MTT) as a preliminary screen for evaluation of in vitro cytotoxicity
J. Cell Sci. Morgan 91 231 1988 10.1242/jcs.91.2.231 Effects of synthetic polycations on leucine incorporation, lactate dehydrogenase release and morphology of human umbilical vein endothelial cells
J. Biol. Chem. Lindsay Bashford 261 9300 1986 10.1016/S0021-9258(18)67654-9 Membrane damage by hemolytic viruses, toxins, complement, and other cytotoxic agents
J. Control. Release Choksakulnimitr 34 233 1995 10.1016/0168-3659(95)00007-U In vitro cytotoxicity of macromolecules in different cell culture systems
Proc. Natl. Acad. Sci. USA Boussif 92 7297 1995 10.1073/pnas.92.16.7297 A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: Polyethylenimine
Nucleic Acids Res. Dong 21 771 1993 10.1093/nar/21.3.771 Efficient DNA transfection of quiescent mammalian cells using poly-L-ornithine
Biopolymers Kabanov 31 1437 1991 10.1002/bip.360311210 DNA interpolyelectrolyte complexes as a tool for efficient cell transformation
Pharm. Res. Cherng 13 1038 1996 10.1023/A:1016054623543 Effect of size and serum proteins on transfection efficiency of poly(2-(dimethylamino)ethyl methacrylate)-plasmid nanoparticles
Proc. Natl. Acad. Sci. USA Kukowska-Latallo 93 4897 1996 10.1073/pnas.93.10.4897 Efficient transfer of genetic material into mammalian cells using Starburst polyamidoamine dendrimers
Nucleic Acids Res. Bielinska 24 2176 1996 10.1093/nar/24.11.2176 Regulation of in vitro gene expression using antisense oligonucleotides or antisense expression plasmids transfected using Starburst PAMAM dendrimers
Biochemistry Haynes 9 4410 1970 10.1021/bi00824a600 Structure of nucleic acid-polybase complexes
Biopolymers Li 13 1681 1974 10.1002/bip.1974.360130813 Helix-coil transition in nucleoprotein. Effect of ionic strength on thermal denaturation of polylysine-DNA complexes
J. Mol. Biol. Olins 24 157 1967 10.1016/0022-2836(67)90324-5 Model nucleoprotein complexes: Studies on the interaction of cationic homopolypeptides with DNA
Adv. Polym. Sci. Ferruti 58 55 1984 10.1007/3-540-12793-3_7 Linear amino polymers: Synthesis, protonation and complex formation
P. Ferruti, Ion-chelating polymers (medical applications), in: J.C. Salamone (Ed. in Chief), Polymeric Materials Encyclopedia, vol. 5 (H-L), CRC, Boca Raton, FL, 1996, pp. 3334-3359.
J. Biomater. Sci. Polym. Edn. Ranucci 2 303 1991 10.1163/156856291X00197 Poly(amidoamine)s with potential as drug carriers: Degradation and cellular toxicity
Biochim. Biophys. Acta Hill 1427 161 1999 10.1016/S0304-4165(99)00021-5 In vitro cytotoxicity of poly(amidoamine)s: Relevance to DNA delivery
Pharm. Res. Ledley 13 1595 1996 10.1023/A:1016420102549 Pharmaceutical approach to somatic gene therapy
J. Control. Release Tomlinson 39 357 1996 10.1016/0168-3659(95)00166-2 Controllable gene-therapy - pharmaceutics of non-viral gene delivery systems
Polymer Danusso 11 88 1970 10.1016/0032-3861(70)90029-7 Synthesis of tertiary amino polymers
Macromol. Synth. Ferruti 9 25 1985 Poly(amido-amine)s
J. Chem. Soc. Faraday Trans. Casolaro 93 3663 1997 10.1039/a703259e Amphoteric poly(amidoamine) polymers containing the ethylene-N,N′-diacetic acid moiety. Stability of copper (II) and calcium (II) chelates
D.P. Knight, P.R. Lewis, Staining Methods for Sectioned Material, Elsevier Biomedical Press, Amsterdam, 1977, p. 84.
Anal. Biochem. Bradford 72 248 1976 10.1016/0003-2697(76)90527-3 A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
Bioconjug. Chem. Wadhwa 6 283 1995 10.1021/bc00033a008 Targeted gene delivery with a low-molecular weight glycopeptide carrier
Gene Ther. Wolfert 3 269 1996 Atomic force microscopic analysis of the influence of the molecular weight of poly-L-lysine on the size of polyelectrolyte complexes formed with DNA
Nucleic Acids Res. Hansma 26 2481 1998 10.1093/nar/26.10.2481 DNA condensation for gene therapy as monitored by atomic force microscopy
Proc. Natl. Acad. Sci. USA Wagner 88 4255 1991 10.1073/pnas.88.10.4255 Transferrin-polycation-DNA complexes: The effect of polycations on the structure of the complex and DNA delivery to cells
Nucleic Acids Res. Dunlap 25 3095 1997 10.1093/nar/25.15.3095 Nanoscopic structure of DNA condensed for gene delivery
J. Mol. Biol. Chattoraj 121 327 1978 10.1016/0022-2836(78)90367-4 DNA condensation with polyamines II. Electron microscopic studies
Biopolymers Bloomfield 44 269 1997 10.1002/(SICI)1097-0282(1997)44:3<269::AID-BIP6>3.0.CO;2-T DNA condensation by multivalent cations
Proc. Natl. Acad. Sci. USA Leng 56 1325 1966 10.1073/pnas.56.4.1325 The preferential interactions of polylysine and polyarginine with specific base sequences in DNA
Biochemistry Shapiro 8 3219 1969 10.1021/bi00836a014 Deoxyribonucleic acid-polylysine complexes. Structure and nucleotide specificity
Macromolecules Bignotti 27 7171 1994 10.1021/ma00102a027 NMR studies, molecular characterisation, and degradation behaviour of poly(amidoamine)s. - 1-Poly(amidoamine) deriving from the polyaddition of 2-methylpiperazine to 1,4-bis(acroyloyl)piperazine
Proc. Natl. Acad. Sci. USA Perales 91 4086 1994 10.1073/pnas.91.9.4086 Gene transfer in vivo: Sustained expression and regulation of genes introduced into the liver by receptor-targeted uptake
Biopolymers Post 21 2123 1982 10.1002/bip.360211104 Theory of DNA condensation: collapse versus aggregation
Biochim. Biophys. Acta Kwoh 1444 171 1999 10.1016/S0167-4781(98)00274-7 Stabilization of poly-L-lysine/DNA polyplexes for in vivo gene delivery to the liver
Gene Ther. Tang 4 823 1997 10.1038/sj.gt.3300454 The influence of polymer structure on the interactions of cationic polymers with DNA and morpology of the resulting complexes
Pharm. Res. Erbacher 15 1332 1998 10.1023/A:1011981000671 Chitosan-based vector/DNA complexes for gene delivery: Biophysical characteristics and transfection ability
Macromolecules Dautzenberg 30 7810 1997 10.1021/ma970803f Polyelectrolyte complex formation in highly aggregating systems. 1. Effect of salt polyelectrolyte complex formation in the presence of NaCl
A.V. Kabanov, F.C. Szoka, L.W. Seymour, Interpolyelectrolyte complexes for gene delivery: Polymer aspects of transfection activity, in: A.V. Kabanov, P.L. Felgner, L.W. Seymour (Eds.) Self-assembling Complexes for Gene Delivery: From Laboratory to Clinical Trial, Wiley and Sons, Chichester, 1998, pp. 197-218.
Adv. Drug Del. Rev. Smith 30 115 1998 10.1016/S0169-409X(97)00111-7 Synthetic peptide-based DNA complexes for nonviral gene delivery
Bioconjug. Chem. Tang 7 703 1996 10.1021/bc9600630 In vitro gene delivery by degraded polyamidoamine dendrimers
J. Colloid Interface Sci. Walker 179 552 1996 10.1006/jcis.1996.0249 Role of polymer flexibility in the stabilization of colloidal particles by model anionic polyelectrolytes
Bioconjug. Chem. Haensler 4 372 1993 10.1021/bc00023a012 Polyamidoamine cascade polymers mediate efficient transfection of cells in culture
Trends Pharm. Sci. Nelson 12 1203 1991 10.1016/0165-6147(91)90501-I Structure and pharmacology of the proton ATPases
Macromolecules Barbucci 14 1203 1981 10.1021/ma50006a013 Macroinorganics, 7: Property-structure relationships for polymeric bases whose monomeric units behave independently towards protonation
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