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[해외논문] Development of a three‐dimensional in vitro co‐culture model to increase drug selectivity for humans

Diabetes, obesity & metabolism, v.22 no.8, 2020년, pp.1302 - 1315  

Park, Sung Bum (Therapeutics and Biotechnology Division, Korea Research Institute of Chemical Technology, Daejeon, Republic of Korea) ,  Koh, Byumseok (Therapeutics and Biotechnology Division, Korea Research Institute of Chemical Technology, Daejeon, Republic of Korea) ,  Jung, Won Hoon (Therapeutics and Biotechnology Division, Korea Research Institute of Chemical Technology, Daejeon, Republic of Korea) ,  Choi, Kyoung Jin (Therapeutics and Biotechnology Division, Korea Research Institute of Chemical Technology, Daejeon, Republic of Korea) ,  Na, Yoon Ju (Therapeutics and Biotechnology Division, Korea Research Institute of Chemical Technology, Daejeon, Republic of Korea) ,  Yoo, Hee Min (Center for Bioanalysis, Division of Chemical and Medical Metrology, Korea Research Institute of Standards and Science, Daejeon, Republic of Korea) ,  Lee, Sunray (Cell Engineering for Origin R) ,  Kang, Dukjin ,  Lee, Dong‐Mok ,  Kim, Ki Young

Abstract AI-Helper 아이콘AI-Helper

AbstractAimInsulin resistance is a metabolic state where insulin sensitivity is lower than normal condition and strongly related to type 2 diabetes. However, an in vitro model mimicking insulin resistance is rare and thus screening drugs for insulin resistance severely depends on an in vivo model. H...

Keyword

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