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[해외논문] Antitumor activity of tributyrin in murine melanoma model

Cancer letters, v.164 no.2, 2001년, pp.143 - 148  

Giermasz, Adam (Department of Immunology, Centre of Biostructure, The Medical University of Warsaw, ul. Chalubinskiego 5, 02-004 Warsaw, Poland) ,  Nowis, Dominika (Department of Immunology, Centre of Biostructure, The Medical University of Warsaw, ul. Chalubinskiego 5, 02-004 Warsaw, Poland) ,  Jalili, Ahmad (Department of Immunology, Centre of Biostructure, The Medical University of Warsaw, ul. Chalubinskiego 5, 02-004 Warsaw, Poland) ,  Basak, Grzegorz (Department of Immunology, Centre of Biostructure, The Medical University of Warsaw, ul. Chalubinskiego 5, 02-004 Warsaw, Poland) ,  Marczak, Maria (Department of Dermatology, The Medical University of Warsaw, Warsaw, Poland) ,  Makowski, Marcin (Department of Immunology, Centre of Biostructure, The Medical University of Warsaw, ul. Chalubinskiego 5, 02-004 Warsaw, Poland) ,  Czajka, Anna (Department of Immunology, Centre of Biostructure, The Medical University of Warsaw, ul. Chalubinskiego 5, 02-004 Warsaw, Poland) ,  Młynarczuk, Izabela (Department of Immunology, Centre of Biostructure, The Medical University of Warsaw, ul. Chalubinskiego 5, 02-004 Warsaw, Poland) ,  Hoser, Grażyna (Department o) ,  Stok osa, Tomasz ,  Lewandowski, Sebastian ,  Jakóbisiak, Marek

Abstract AI-Helper 아이콘AI-Helper

AbstractButyric acid has been known to inhibit growth and to induce differentiation of a variety of tumor cells. Butyrate-treated tumor cells have also been observed to undergo apoptosis. Although butyrate compounds have demonstrated antitumor activity in murine tumor models and have already been ad...

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참고문헌 (19)

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  2. Cancer Res. Augeron 44 3961 1984 Emergence of permanently differentiated cell clones in a human colonic cancer cell line in culture after treatment with sodium butyrate 

  3. Cancer Res. Abe 44 4574 1984 Sodium butyrate induction of milk-related antigens in human MCF-7 breast carcinoma cells 

  4. Cell Growth Differ. Vaziri 9 465 1998 Butyrate-induced G1 arrest results from p21-independent disruption of retinoblastoma protein-mediated signals 

  5. Cancer Res. Heerdt 59 1584 1999 Initiation of growth arrest and apoptosis of MCF-7 mammary carcinoma cells by tributyrin, a triglyceride analogue of the short-chain fatty acid butyrate, is associated with mitochondrial activity 

  6. Exp. Cell Res. Lallemand 247 432 1999 10.1006/excr.1998.4370 Sodium butyrate induces G2 arrest in the human breast cancer cells MDA-MB-231 and renders them competent for DNA rereplication 

  7. Int. J. Cancer Hague 55 498 1993 10.1002/ijc.2910550329 Sodium butyrate induces apoptosis in human colonic tumour cell lines in a p53-independent pathway: implications for the possible role of dietary fibre in the prevention of large-bowel cancer 

  8. J. Cancer Res. Clin. Oncol. Zimra 123 152 1997 10.1007/BF01214667 Butyric acid and pivaloyloxymethyl butyrate, AN-9, a novel butyric acid derivative, induce apoptosis in HL-60 cells 

  9. Tohoku J. Exp. Med. Kimura 131 29 1980 10.1620/tjem.131.29 Differentiative and proliferative effects of (But)2cAMP, n-butyric acid and prednisolone on the malignant melanoma cell line (TM-1) in vitro and in vivo 

  10. J. Med. Chem. Nudelman 35 687 1992 10.1021/jm00082a009 Novel anticancer prodrugs of butyric acid, 2 

  11. Br. J. Cancer Kasukabe 75 850 1997 10.1038/bjc.1997.151 An anti-cancer derivative of butyric acid (pivalyloxmethyl buterate) and daunorubicin cooperatively prolong survival of mice inoculated with monocytic leukaemia cells 

  12. Clin. Cancer Res. Conley 4 629 1998 Phase I study of the orally administered butyrate prodrug, tributyrin, in patients with solid tumors 

  13. Cancer Immunol. Immunother. Douillard 49 56 2000 10.1007/s002620050026 Phase I trial of interleukin-2 and high-dose arginine butyrate in metastatic colorectal cancer 

  14. Cancer Immunol. Immunother. Lasek 40 315 1995 10.1007/BF01519632 Potentiation of antitumor effects of tumor necrosis factor alpha and interferon gamma by macrophage-colony-stimulating factor in a MmB16 melanoma model in mice 

  15. Methods Cell Biol. Crissman 41 195 1994 10.1016/S0091-679X(08)61718-5 Staining of DNA in live and fixed cells 

  16. Ann. Oncol. Golab 9 63 1998 10.1023/A:1008266321552 G-CSF prevents the suppression of bone marrow hematopoiesis induced by IL-12 and augments its antitumor activity in a melanoma model in mice 

  17. Int. J. Cancer Majewski 57 81 1994 10.1002/ijc.2910570115 Synergistic effect of retinoids and interferon alpha on tumor-induced angiogenesis: anti-angiogenic effect on HPV-harboring tumor-cell lines 

  18. Brain Res. Nuydens 688 86 1995 10.1016/0006-8993(95)00514-Q Sodium butyrate induces aberrant tau phosphorylation and programmed cell death in human neuroblastoma cells 

  19. Biochem. Biophys. Res. Commun. Chang 221 594 1996 10.1006/bbrc.1996.0641 Potentiation of sodium butyrate-induced apoptosis by vanadate in human promyelocytic leukemia cell line HL-60 

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