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[해외논문] Protective responses against experimental Mycobacterium leprae infection in mice induced by recombinant Bacillus Calmette-Guérin over-producing three putative protective antigen candidates

Vaccine, v.19 no.15/16, 2001년, pp.1906 - 1910  

Ohara, Naoya (Nagasaki University School of Dentistry, Sakamoto 1-7-1, Nagasaki, 852-8588, Japan) ,  Matsuoka, Masanori (Leprosy Research Center, National Institute of Infectious Diseases, 2-1, 4 Chome, Aoba-cho, Higashimurayama, Tokyo, 189-0002, Japan) ,  Nomaguchi, Hiroko (Leprosy Research Center, National Institute of Infectious Diseases, 2-1, 4 Chome, Aoba-cho, Higashimurayama, Tokyo, 189-0002, Japan) ,  Naito, Mariko (Nagasaki University School of Dentistry, Sakamoto 1-7-1, Nagasaki, 852-8588, Japan) ,  Yamada, Takeshi (Nagasaki University School of Dentistry, Sakamoto 1-7-1, Nagasaki, 852-8588, Japan)

Abstract AI-Helper 아이콘AI-Helper

AbstractThe components of Ag85 (Ag85A, Ag85B, and Ag85C) are putative protective antigen candidates against mycobacterial infection. A recombinant Mycobacterium bovis Bacillus Calmette-Guérin (rBCG) over-producing Ag85A, Ag85B, and MPB51 (rBCG/BA51) was constructed. rBCG/BA51 could secrete th...

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