$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

Validation of pharmacological activity and anti-pollution effect of ethanol extract of Azadirachta indica leaf
님트리(Azadirachta indica)잎 에탄올추출물의 약리활성 및 안티폴루션 효능 검증 원문보기

한국식품저장유통학회지 = Korean journal of food preservation, v.27 no.3, 2020년, pp.393 - 406  

Hyun, Jin A ,  Lee, Ji Hye ,  Kang, Eun Bin ,  Kim, Hyun Jeong ,  Kim, Dong In ,  Park, Ga Eun ,  Kwak, Ki Sung ,  An, Bong Jeon

Abstract AI-Helper 아이콘AI-Helper

In this study, we investigated the anti-oxidant, anti-inflammatory, whitening, anti-wrinkle, and anti-pollution effects of Neem tree (i.e., Azadirachta indica leaf) 70% ethanol extract. More specifically, the polyphenol content was 51.37 mg/g, and the DPPH and ABTS radical scavenging activities were...

참고문헌 (54)

  1. An BJ, Lee JT, Lee CE. Novel Cosmetic Material. Gwangmungak, Paju, Korea, p 82 (2009) 

  2. Bagchi D. Green Tea. Antioxidant Power to Fight Disease. Keats Publishing, New Canaan, CT, USA, p 48 (1999) 

  3. 10.1152/physrev.1998.78.2.547 Beckman KB, Ames BN. The free radical theory of again matures. Pysiol Rev, 78:547-581 (1993) 10.1152/physrev.1998.78.2.547, 9562038 

  4. 10.1152/physrev.1998.78.2.547 Beckman KB, Ames BN. The free radical theory of aging matures. Physiol Rev, 78, 547-581 (1998) 10.1152/physrev.1998.78.2.547, 9562038 

  5. 10.1038/1811199a0 Blois MS. Antioxidant determinations by the use of a stable free radical. Nature, 181, 1199-1200 (1958) 10.1038/1811199a0 

  6. 10.1111/j.1749-6632.2002.tb04602.x Brenneisen P, Sies H, Scharffetter-Kochanek K. Ultraviolet-B irradiation and matrix metalloproteinases: From induction via signaling to initial events. Ann N Y Acad Sci, 973, 31-43 (2002) 10.1111/j.1749-6632.2002.tb04602.x, 12485830 

  7. 10.1021/jo01031a044 Brieskorn CH, Fuchs A, Bredenberg JB, McChesney Jd, Wenkert E. The structure of carnosol. J Org Chem, 29, 2293-2298 (1964) 10.1021/jo01031a044 

  8. 10.1111/j.2042-7158.1994.tb03253.x Cabanes J, Chazarra S, Garcia-Carmona F. Kojic acid, a cosmetic skin whitening agent, is a slow-blinding inhibitor of catecholase activity of tyrosinase. J Pharm Pharmacol, 46, 982-985 (1994) 10.1111/j.2042-7158.1994.tb03253.x, 7714722 

  9. 10.1055/s-2006-962319 Cannell RJ, Kellam SJ, Owsianka AM, Walker JM. Results of a large scale screen of microalgae for the production of protease inhibitors. Planta Med, 54, 10-14 (1988) 10.1055/s-2006-962319, 3375330 

  10. Carmichael J, DeGraff WG, Gazdar AF, Minna JD, Mitchell JB. Evaluation of a tetrazolium-based semiautomated colorimetric assay: Assessment of chemosensitivity testing. Cancer Res, 47, 936-942 (1987) 

  11. 10.3390/ijms140917643 Cencioni C, Spallotta F, Martelli F, Valente S, Mai A, Zeiher AM, Gaetano C. Oxidative stress and epigenetic regulation in ageing and age-related diseases. Int J Mol Sci, 14, 17643-17663 (2013) 10.3390/ijms140917643, 23989608, PMC3794746 

  12. Cho YJ, An BJ. Anti-inflammatory effect of extracts from Cheongmoknosang (Morus alba L.) in lipopolysaccharide-stimulated RAW cells. J Korean Soc Appl Biol Chem, 51, 44-48 (2008) 

  13. Choi JH. The Role of Oxygen Radicals in Aging Process. October 1, Bugyong University, Korea, p 2 (1998) 

  14. Choi SM, Kim CD, Lee MH, Choi YH, Rang MJ, Ahn HJ, Yun YP. Screening of 5α-reductase inhibition and comedolytic effects from natural products. Yakhak Hoeji, 43, 342-350 (1999) 

  15. Clayton T, Soralump P, Chaukul W, Temsiririrkkul R. Medicinal Plants in Thailand, Volume 1. Amarin Printing and Publishing PuKlic, Bangkok, p 44 (1996) 

  16. 10.1128/aem.47.2.229-233.1984 Conner DE, Beuchat LR. Sensitivity of heat-stressed yeasts to essential oils of plants. Appl Enuiron Microbial, 47, 229-233 (1984) 10.1128/AEM.47.2.229-233.1984 

  17. 10.1006/excr.2001.5348 Dale BA, Fleckman P, Kuechle MK, Lewis S, Presland RB. Regulated expression of human filaggrin in keratinocytes results in cytoskeletal disruption, loss of cell-cell adhesion, and cell cycle arrest. Exp Cell Res, 270, 199-213 (2001) 10.1006/excr.2001.5348, 11640884 

  18. 10.1517/13543780903203789 Ding C, Cicuttini F, Li J, Jones G. Targeting IL-6 in the treatment of inflammatory and autoimmune diseases. Expert Opin Invest Drugs, 18, 1457-1466 (2009) 10.1517/13543780903203789, 19715447 

  19. 10.1007/978-3-0348-7460-1_33 Emerit I. Free Radicals and Aging of the Skin. In: Free Radicals and Aging, Emerit I, Chance B (Editors), Birkhauser Verlag, Basel, Switzerland, p 328-341 (1992) 10.1007/978-3-0348-7460-1_33, 1450595 

  20. 10.1007/s13594-012-0072-7 Farhang B, Kakuda Y, Corredig M. Encapsulation of ascorbic acid in liposomes prepared with milk fat globule membrane-derived phospholipids. Dairy Sci Technol, 92, 353-366 (2012) 10.1007/s13594-012-0072-7 

  21. 10.4049/jimmunol.163.12.6403 Feng GJ, Goodridge HS, Harnett MM, Wei XQ, Nikolaev AV, Higson AP, Liew FY. Extracellular signal-related kinase (ERK) and p38 mitogen-activated protein (MAP) kinases differentially regulate the lipopolysaccharidemediated induction of inducible nitric oxide synthase and IL-12 in macrophages: Leishmania phosphoglycans subvert macrophage IL-12 production by targeting ERK MAP kinase. J Immunol, 163, 6403-6412 (1999) 

  22. 10.1172/JCI2153 Fisher GJ, Talwar HS, Lin J, Lin P, McPhillips F, Wang Z, Li X, Wan Y, Kang S, Voorhees JJ. Retinoic acid inhibits induction of c-Jun protein by ultraviolet radiation that occurs subsequent to activation of mitogen-activated protein kinase pathways in human skin in vivo. J Clin Invest, 15, 1432-1440 (1998) 10.1172/JCI2153, 9502786, PMC508699 

  23. 10.1016/S0021-9258(18)88697-5 Folin O, Denis W. On phosphotungastic-phosphomolybdic compounds as color reagents. J Biol Chem, 12, 239-249 (1912) 

  24. 10.1016/S0021-9258(18)62884-4 Fridovich I. Quantitative aspects of the production of superoxide anion radical by milk xanthine oxidase. J Bio Chem, 245, 4053-4057 (1970) 

  25. 10.1146/annurev.immunol.16.1.225 Ghosh S, May MJ, Kopp EB. NF-κ B and Rel proteins: Evolutionarily conserved mediators of immune responses. Annu Rev Immunol, 16, 225-260 (1998) 10.1146/annurev.immunol.16.1.225, 9597130 

  26. 10.1007/s004170050241 Grasbon T, Grasbon-Frodl EM, Juliusson B, Epstein C, Brundin P, Kampik A, Ehinger B. CuZn superoxide dismutase transgenic retinal transplants. Graefes Arch Clin Exp Ophthalmol, 237, 336-341 (1999) 10.1007/s004170050241, 10208267 

  27. 10.1016/0003-2697(82)90118-X Green LC, Wagner DA, Glogowski J, Skipper PL, Wishnok JS, Tannenbaum SR. Analysis of nitrate, nitrite, and [15N] nitrate in biological fluids. Anal Biochem, 126, 131-138 (1982) 10.1016/0003-2697(82)90118-X 

  28. 10.1016/S0898-6568(00)00149-2 Guha M, Mackman N. LPS induction of gene expression in human monocytes. Cell Signalling, 13, 85-94 (2001) 10.1016/S0898-6568(00)00149-2 

  29. 10.1016/S0898-6568(02)00053-0 Haddad JJ. Antioxidant and prooxidant mechanisms in the regulation of reodox(y)-sensitive transcription factors. Cell Signalling, 14, 879-897 (2002) 10.1016/S0898-6568(02)00053-0 

  30. 10.1016/S0898-6568(02)00053-0 Haddad JJ. Antioxidnat and prooxidant mechanisms in the regulation of redox (y)-sensitive transcription factors. Cell Signalling, 14, 879-897 (2002) 10.1016/S0898-6568(02)00053-0 

  31. Im S, Moro O, Peng F, Medrano EE, Cornelius J, Babcock G, Nordlund JJ, Abdel-Malek ZA. Activation of the cyclic AMP pathway by α-melanotropin mediates the response of human melanocytes to ultraviolet B radiation. Cancer Res, 58, 47-54 (1998) 

  32. 10.1078/094471103321648638 Jain A, Basal E. Inhibition of Propionibacterium acnesinduced mediators of inflammation by indian berbs. Phytomedicine, 10, 34-38 (2003) 10.1078/094471103321648638, 12622461 

  33. 10.1111/j.1600-0749.1995.tb00648.x Kameyama K, Sakai C, Kuge S, Nishiyama S, Tomita Y, Ito S, Wakamatsu K, Hearing VJ. The expression of tyrosinase, tyrosinase-related proteins 1 and 2 (TRP1 and TRP2), the silver protein, and a melanogenic inhibitor in human melanoma cells of differing melanogenic activities. Pigmant Cell Res, 8, 97-104 (1995) 10.1111/j.1600-0749.1995.tb00648.x, 7659683 

  34. 10.1186/1756-6606-5-14 Kandel ER. The molecular biology of memory: cAMP, PKA, CRE, CREB-1, CREB-2, and CPEB. Mol Brain, 5, 14 (2012) 10.1186/1756-6606-5-14, 22583753, PMC3514210 

  35. Kang SO, Lee KK, Choi JD. Free radical scavenging activity and characterization of the extracts from Alpinia katsumadai and Areca catechu. J Korean Cosmet Scientists Korea, 27, 133-150 (2001) 

  36. 10.1016/j.mrrev.2008.03.002 Kundu JK, Surh YJ. Inflammation: Gearing the journey to cancer. Mutat Res, 659, 15-30 (2008) 10.1016/j.mrrev.2008.03.002, 18485806 

  37. Lee JY, Park WS, Son ED, Ahn SM, Hwang JS. In vitro evaluation methods for development of cosmeceutical ingredients. J Altern Anim Exp, 1, 33-40 (2007) 

  38. 10.1111/j.1432-1033.1974.tb03714.x Marklund S, Marklund G. Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem, 47, 469-474 (1974) 10.1111/j.1432-1033.1974.tb03714.x, 4215654 

  39. 10.1016/0014-5793(96)00109-3 Marmol V, Beermann F, Veronique M, Friedrich B. Tyrosinase and related proteins in mammalian pigmentation. FFBS Lett, 381, 165-168 (1996) 10.1016/0014-5793(96)00109-3 

  40. 10.1104/pp.122.4.1427 Mckersie BD, Murnaghan J, Jones KS, Bowley SR. Ironsuperoxide dismutase expression in transgenic alfalfa increases winter survival without a detectable increase in photosynthetic oxidative stress tolerance. Plant Physiol, 122, 1427-1437 (2000) 10.1104/pp.122.4.1427, 10759538, PMC58977 

  41. 10.1038/nature07201 Medzhitov R. Origin and physiological roles of inflammation. Nature, 454, 428-435 (2008) 10.1038/nature07201, 18650913 

  42. Molyneux P. The use of the stable free radical diphenylpiecrylhydrazyl (DPPH) for estimating antioxidant activity. Songklanakarin J Sci Technol, 26, 211-219 (2004) 

  43. Moon JS, Kim SJ, Par YM, Hwang IS, Kim EH, Park JW, Park IB, Kim SW, Kang SG, Park YK, Jung ST. Antimicrobial effect of methanol extracts from some medicinal herbs and the contest of phenolic compounds. Korean J Food Preserv, 11, 207-213 (2004) 

  44. Park SH, Cho CH, Ahn BY. A study on the application of Gastrodiae rhizoma for food stuffs - Effects of Gastrodiae rhizoma on the regional cerebral blood flow and blood pressure. J East Asian Soc Dietary Life, 17, 554-562 (2007) 

  45. 10.1111/1523-1747.ep12616142 Petersen MJ, Hansen C, Craig S. Ultraviolet A irradiation stimulates collagenase production in cultured human fibroblasts. J Invest Dermatol, 99, 440-444 (1992) 10.1111/1523-1747.ep12616142, 1402002 

  46. 10.1007/s002109900150 Posadas I, Terencio MC, Guillen I, Ferrandiz ML, Coloma J, Paya M, Alcaraz MJ. Co-regulation between cyclooxyenase-2 and inducible nitric oxide synthase expression in the time-course of murine inflammation. NaunynSchmiedeberg’s Arch of Pharmacol, 361, 98-106 (2000) 10.1007/s002109900150, 10651154 

  47. 10.3109/10715769509145649 Rice-Evans CA, Miller NJ, Bolwell PG, Bramley PM, Pridham JB. The relative antioxidant activities of plant-derived polyphenolic flavonoids. Free Radical Res, 22, 375-383 (1995) 10.3109/10715769509145649, 763356 

  48. Shin JH, Kang JR, Kang MJ, Shin JH. Physiological activity of five kinds of medicinal plant extracts with various solvents and their composites. J Life Sci, 28, 320-330 (2018) 

  49. Shin JY. Screening of natural products that have activities against skin-aging. Korean J Food Nutr, 14, 568-572 (2001) 

  50. 10.1002/aja.1001750409 Smith LT, Holbrook KA, Madri JA. Collagen types I, III, and IV in human embryonic and fetal skin. Am J Anat, 175, 507-521 (1986) 10.1002/aja.1001750409, 3521252 

  51. Steskova A, Morochovicova M, Leskova E. Vitamin C degradation during storage of fortified foods. J Food Nutr Res, 45, 55-61 (2006) 

  52. 10.1016/0378-8741(91)90131-V van der Nat JM, van der Sluis WG, Silva KTD, Labadie RP. Ethnopharmacognostical survey of Azadirachta indica A. Juss (Meliaceae). J Ethnopharmacol, 35, 1-24 (1991) 10.1016/0378-8741(91)90131-V 

  53. 10.1074/jbc.274.46.33043 Wang Y, Johnson AR, Ye QZ, Dyer RD. Catalytic activities and substrate specificity of the human membrane type 4 matrix metalloproteinase catalytic domain. J Biol Chem, 274, 33043-33049 (1999) 10.1074/jbc.274.46.33043, 10551873 

  54. 10.1055/s-2007-969126 Yagi A, Kanbara T, Morinobu N. The effect of tyrosinase inhibition for aloe. Planta Med, 52, 517-519 (1986) 

관련 콘텐츠

오픈액세스(OA) 유형

GOLD

오픈액세스 학술지에 출판된 논문

저작권 관리 안내
섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로