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NTIS 바로가기International journal of pharmaceutics, v.565, 2019년, pp.162 - 173
Ramos, Irina (Purification Process Sciences Department, Medimmune LLC, One Medimmune Way) , Lourenço, Eva C. (Extremochem) , Ascenso, Osvaldo S. (Extremochem) , Maycock, Christopher D. (Faculdade de Ciê) , Dasika, Madhukar (ncias da Universidade de Lisboa, Departamento de Quí) , Dickson, Matthew L. (mica e Bioquí) , Ventura, M. Rita (mica)
Abstract Determining the stability of downstream process (DSP) intermediates is an extremely important parameter used to maintain product quality attributes within their acceptance ranges. The IgG4 monoclonal antibody studied (mAb1) showed aggregation under acidic conditions, inhibiting the use of ...
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