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Ergothioneine alleviates senescence of fibroblasts induced by UVB damage of keratinocytes via activation of the Nrf2/HO-1 pathway and HSP70 in keratinocytes

Experimental cell research, v.400 no.1, 2021년, pp.112516 -   

Ko, Hyun Ju (Department of Veterinary Anatomy, College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University) ,  Kim, Jeongtae (Department of Anatomy, Kosin University College of Medicine) ,  Ahn, Meejung (Department of Animal Science, College of Life Science, Sangji University) ,  Kim, Jin Hwa (Skin science research team, Creation & Innovation research institute, It's hanbul Co., LTD.) ,  Lee, Geun Soo (Skin science research team, Creation & Innovation research institute, It's hanbul Co., LTD.) ,  Shin, Taekyun (Department of Veterinary Anatomy, College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University)

Abstract AI-Helper 아이콘AI-Helper

Abstract Ultraviolet B (UVB) irradiation induces skin damage and photoaging through several deleterious effects, including generation of reactive oxygen species (ROS), apoptosis of epidermal cells, inflammation, and collagen degradation in fibroblasts. Ergothioneine (EGT) is a naturally occurring a...

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