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NTIS 바로가기Cell reports, v.34 no.8, 2021년, pp.108780 -
Kweon, Hanseul (Department of Biological Sciences, Korea Advanced Institute for Science and Technology (KAIST)) , Jung, Won Beom (Center for Neuroscience Imaging Research (CNIR), Institute for Basic Science (IBS)) , Im, Geun Ho (Center for Neuroscience Imaging Research (CNIR), Institute for Basic Science (IBS)) , Ryoo, Jia (Department of Biological Sciences, Korea Advanced Institute for Science and Technology (KAIST)) , Lee, Joon-Hyuk (Department of Biological Sciences, Korea Advanced Institute for Science and Technology (KAIST)) , Do, Hogyeong (Center for Synaptic Brain Dysfunctions, Institute for Basic Science (IBS)) , Choi, Yeonsoo (Center for Synaptic Brain Dysfunctions, Institute for Basic Science (IBS)) , Song, You-Hyang (Department of Biological Sciences, Korea Advanced Institute for Science and Technology (KAIST)) , Jung, Hwajin (Center for Synaptic Brain Dysfunctions, Institute for Basic Science (IBS) Korea<) , Park, Haram , Qiu, Lily R. , Ellegood, Jacob , Shim, Hyun-Ji , Yang, Esther , Kim, Hyun , Lerch, Jason P. , Lee, Seung-Hee , Chung, Won-Suk , Kim, Daesoo , Kim, Seong-Gi , Kim, Eunjoon
Summary CHD8 (chromodomain helicase DNA-binding protein 8) is a chromatin remodeler associated with autism spectrum disorders. Homozygous Chd8 deletion in mice leads to embryonic lethality, making it difficult to assess whether CHD8 regulates brain development and whether CHD8 haploinsufficiency-re...
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