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[해외논문] TXNIP Regulates Natural Killer Cell-Mediated Innate Immunity by Inhibiting IFN-γ Production during Bacterial Infection 원문보기

International journal of molecular sciences, v.21 no.24, 2020년, pp.9499 -   

Kim, Dong Oh (Department of Innovative Toxicology Research, Korea Institute of Toxicology, Yuseong-gu, Daejeon 34114, Korea) ,  Byun, Jae-Eun (dongoh.kim@kitox.re.kr) ,  Kim, Won Sam (Immunotherapy Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Yuseong-gu, Daejeon 34141, Korea) ,  Kim, Mi Jeong (quswodms@kribb.re.kr (J.-E.B.)) ,  Choi, Jung Ha (kwasa@ensolbio.co.kr (W.S.K.)) ,  Kim, Hanna (cjhsong5284@kribb.re.kr (J.H.C.)) ,  Choi, Eunji (hanna@kribb.re.kr (H.K.)) ,  Kim, Tae-Don (vnfmsgksmf89@kribb.re.kr (E.C.)) ,  Yoon, Suk Ran (tdkim@kribb.re.kr (T.-D.K.)) ,  Noh, Ji-Yoon (sryoon@kribb.re.kr (S.R.Y.)) ,  Park, Young-Jun (nohj16@kribb.re.kr (J.-Y.N.)) ,  Lee, Jungwoon (hjcho@kribb.re.kr (H.J.C.)) ,  Cho, Hee Jun (hglee@kribb.re.kr (H.G.L.)) ,  Lee, Hee Gu (Immunotherapy Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Yuseong-gu, Daejeon 34141, Korea) ,  Min, Sang-Hyun (quswodms@kribb.re.kr (J.-E.B.)) ,  Choi, Inpyo (kwasa@ensolbio.co.kr (W.S.K.)) ,  Jung, Haiyoung (cjhsong5284@kribb.re.k)

Abstract AI-Helper 아이콘AI-Helper

The function of natural killer (NK) cell-derived interferon-γ (IFN-γ) expands to remove pathogens by increasing the ability of innate immune cells. Here, we identified the critical role of thioredoxin-interacting protein (TXNIP) in the production of IFN-γ in NK cells during bacteri...

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