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NTIS 바로가기Journal of orthopaedic translation, v.23, 2020년, pp.38 - 52
Lo, Jessica Hiu-tung (Department of Orthopaedics & Traumatology, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, PR China) , U, Kin Pong (Department of Orthopaedics & Traumatology, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, PR China) , Yiu, Tszlam (Department of Orthopaedics & Traumatology, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, PR China) , Ong, Michael Tim-yun (Department of Orthopaedics & Traumatology, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, PR China) , Lee, Wayne Yuk-wai (Department of Orthopaedics & Traumatology, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, PR China)
Sarcopenia is characterized by loss of muscle and reduction in muscle strength that contributes to higher mortality rate and increased incidence of fall and hospitalization in the elderly. Mitochondria dysfunction and age-associated inflammation in muscle are two of the main attributors to sarcopeni...
1 Beard J.R. Officer A.M. Cassels A.K. The World report on ageing and health Gerontol 56 Suppl 2 2016 S163 S166
2 Lexell J. Taylor C.C. Sjostrom M. What is the cause of the ageing atrophy? Total number, size and proportion of different fiber types studied in whole vastus lateralis muscle from 15- to 83-year-old men J?Neurol Sci 84 2?3 1988 275 294 3379447
3 Rosenberg I.H. Sarcopenia: origins and clinical relevance J?Nutr 127 5 Suppl 1997 990S-1S
4 Beaudart C. Zaaria M. Pasleau F. Reginster J.Y. Bruyere O. Health outcomes of sarcopenia: a systematic review and meta-analysis PloS One 12 1 2017 e0169548
5 Sayer A.A. Dennison E.M. Syddall H.E. Gilbody H.J. Phillips D.I. Cooper C. Type 2 diabetes, muscle strength, and impaired physical function: the tip of the iceberg? Diabetes Care 28 10 2005 2541 2542 16186295
6 Prado C.M. Cushen S.J. Orsso C.E. Ryan A.M. Sarcopenia and cachexia in the era of obesity: clinical and nutritional impact Proc Nutr Soc 75 2 2016 188 198 26743210
7 Fielding R.A. Vellas B. Evans W.J. Bhasin S. Morley J.E. Newman A.B. Sarcopenia: an undiagnosed condition in older adults. Current consensus definition: prevalence, etiology, and consequences. International working group on sarcopenia J?Am Med Dir Assoc 12 4 2011 249 256 21527165
8 Cruz-Jentoft A.J. Bahat G. Bauer J. Boirie Y. Bruyere O. Cederholm T. Sarcopenia: revised European consensus on definition and diagnosis Age Ageing 48 1 2019 16 31 30312372
9 Cruz-Jentoft A.J. Baeyens J.P. Bauer J.M. Boirie Y. Cederholm T. Landi F. Sarcopenia: European consensus on definition and diagnosis: report of the European working group on sarcopenia in older people Age Ageing 39 4 2010 412 423 20392703
10 Burton L.A. Sumukadas D. Optimal management of sarcopenia Clin Interv Aging 5 2010 217 228 20852669
11 Sakellariou G.K. Vasilaki A. Palomero J. Kayani A. Zibrik L. McArdle A. Studies of mitochondrial and nonmitochondrial sources implicate nicotinamide adenine dinucleotide phosphate oxidase(s) in the increased skeletal muscle superoxide generation that occurs during contractile activity Antioxidants Redox Signal 18 6 2013 603 621
12 Short K.R. Bigelow M.L. Kahl J. Singh R. Coenen-Schimke J. Raghavakaimal S. Decline in skeletal muscle mitochondrial function with aging in humans Proc Natl Acad Sci U S A 102 15 2005 5618 5623 15800038
13 Palomero J. Vasilaki A. Pye D. McArdle A. Jackson M.J. Aging increases the oxidation of dichlorohydrofluorescein in single isolated skeletal muscle fibers at rest, but not during contractions Am J Physiol Regul Integr Comp Physiol 305 4 2013 R351 R358 23697797
14 Broome C.S. Kayani A.C. Palomero J. Dillmann W.H. Mestril R. Jackson M.J. Effect of lifelong overexpression of HSP70 in skeletal muscle on age-related oxidative stress and adaptation after nondamaging contractile activity Faseb J 20 9 2006 1549 1551 16723383
15 Lopez-Otin C. Blasco M.A. Partridge L. Serrano M. Kroemer G. The hallmarks of aging Cell 153 6 2013 1194 1217 23746838
16 Marzetti E. Leeuwenburgh C. Skeletal muscle apoptosis, sarcopenia and frailty at old age Exp Gerontol 41 12 2006 1234 1238 17052879
17 Garcia-Prat L. Sousa-Victor P. Munoz-Canoves P. Functional dysregulation of stem cells during aging: a focus on skeletal muscle stem cells FEBS J 280 17 2013 4051 4062 23452120
18 Li C.W. Yu K. Shyh-Chang N. Li G.X. Jiang L.J. Yu S.L. Circulating factors associated with sarcopenia during ageing and after intensive lifestyle intervention J?Cachexia Sarcopenia Muscle 10 3 2019 586 600 30969486
19 Mittal K.R. Logmani F.H. Age-related reduction in 8th cervical ventral nerve root myelinated fiber diameters and numbers in man J?Gerontol 42 1 1987 8 10 3794203
20 Pannerec A. Springer M. Migliavacca E. Ireland A. Piasecki M. Karaz S. A?robust neuromuscular system protects rat and human skeletal muscle from sarcopenia Aging (Albany NY) 8 4 2016 712 729 27019136
21 Alway S.E. Degens H. Krishnamurthy G. Chaudhrai A. Denervation stimulates apoptosis but not Id2 expression in hindlimb muscles of aged rats J?Gerontol A Biol Sci Med Sci 58 8 2003 687 697 12902526
22 Siu P.M. Alway S.E. Mitochondria-associated apoptotic signalling in denervated rat skeletal muscle J?Physiol 565 Pt 1 2005 309 323 15774533
23 Morat T. Gilmore K.J. Rice C.L. Neuromuscular function in different stages of sarcopenia Exp Gerontol 81 2016 28 36 27108183
24 Bueler H. Mitochondrial dynamics, cell death and the pathogenesis of Parkinson's disease Apoptosis 15 11 2010 1336 1353 20131004
25 Xie L.L. Shi F. Tan Z. Li Y. Bode A.M. Cao Y. Mitochondrial network structure homeostasis and cell death Cancer Sci 109 12 2018 3686 3694 30312515
26 Nakada K. Inoue K. Ono T. Isobe K. Ogura A. Goto Y.I. Inter-mitochondrial complementation: mitochondria-specific system preventing mice from expression of disease phenotypes by mutant mtDNA Nat Med 7 8 2001 934 940 11479626
27 Yoneda M. Miyatake T. Attardi G. Complementation of mutant and wild-type human mitochondrial DNAs coexisting since the mutation event and lack of complementation of DNAs introduced separately into a cell within distinct organelles Mol Cell Biol 14 4 1994 2699 2712 8139569
28 Alway S.E. Mohamed J.S. Myers M.J. Mitochondria initiate and regulate sarcopenia Exerc Sport Sci Rev 45 2 2017 58 69 28098577
29 Carter H.N. Chen C.C. Hood D.A. Mitochondria, muscle health, and exercise with advancing age Physiology 30 3 2015 208 223 25933821
30 Ryan M.J. Jackson J.R. Hao Y. Leonard S.S. Alway S.E. Inhibition of xanthine oxidase reduces oxidative stress and improves skeletal muscle function in response to electrically stimulated isometric contractions in aged mice Free Radic Biol Med 51 1 2011 38 52 21530649
31 McKenzie D. Bua E. McKiernan S. Cao Z. Aiken J.M. Jonathan W. Mitochondrial DNA deletion mutations: a causal role in sarcopenia Eur J Biochem 269 8 2002 2010 2015 11985577
32 Herbst A. Wanagat J. Cheema N. Widjaja K. McKenzie D. Aiken J.M. Latent mitochondrial DNA deletion mutations drive muscle fiber loss at old age Aging Cell 15 6 2016 1132 1139 27561813
33 Sebastian D. Sorianello E. Segales J. Irazoki A. Ruiz-Bonilla V. Sala D. Mfn2 deficiency links age-related sarcopenia and impaired autophagy to activation of an adaptive mitophagy pathway EMBO J 35 15 2016 1677 1693 27334614
34 Joseph A.M. Adhihetty P.J. Wawrzyniak N.R. Wohlgemuth S.E. Picca A. Kujoth G.C. Dysregulation of mitochondrial quality control processes contribute to sarcopenia in a mouse model of premature aging PloS One 8 7 2013 e69327
35 Zhu Y. Armstrong J.L. Tchkonia T. Kirkland J.L. Cellular senescence and the senescent secretory phenotype in age-related chronic diseases Curr Opin Clin Nutr Metab Care 17 4 2014 324 328 24848532
36 Nelson G. Kucheryavenko O. Wordsworth J. von Zglinicki T. The senescent bystander effect is caused by ROS-activated NF-kappaB signalling Mech Ageing Dev 170 2018 30 36 28837845
37 Jurk D. Wilson C. Passos J.F. Oakley F. Correia-Melo C. Greaves L. Chronic inflammation induces telomere dysfunction and accelerates ageing in mice Nat Commun 2 2014 4172 24960204
38 Bian A.L. Hu H.Y. Rong Y.D. Wang J. Wang J.X. Zhou X.Z. A?study on relationship between elderly sarcopenia and inflammatory factors IL-6 and TNF-alpha Eur J Med Res 22 1 2017 25 28701179
39 Dirks A. Leeuwenburgh C. Apoptosis in skeletal muscle with aging Am J Physiol Regul Integr Comp Physiol 282 2 2002 R519 R527 11792662
40 Phillips T. Leeuwenburgh C. Muscle fiber specific apoptosis and TNF-alpha signaling in sarcopenia are attenuated by life-long calorie restriction Faseb J 19 6 2005 668 670 15665035
41 Perandini L.A. Chimin P. Lutkemeyer D.D.S. Camara N.O.S. Chronic inflammation in skeletal muscle impairs satellite cells function during regeneration: can physical exercise restore the satellite cell niche? FEBS J 285 11 2018 1973 1984 29473995
42 Yin H. Price F. Rudnicki M.A. Satellite cells and the muscle stem cell niche Physiol Rev 93 1 2013 23 67 23303905
43 Rudnicki M.A. Le Grand F. McKinnell I. Kuang S. The molecular regulation of muscle stem cell function Cold Spring Harbor Symp Quant Biol 73 2008 323 331 19329572
44 Collins C.A. Zammit P.S. Ruiz A.P. Morgan J.E. Partridge T.A. A?population of myogenic stem cells that survives skeletal muscle aging Stem Cell 25 4 2007 885 894
45 Jang Y.C. Sinha M. Cerletti M. Dall'Osso C. Wagers A.J. Skeletal muscle stem cells: effects of aging and metabolism on muscle regenerative function Cold Spring Harbor Symp Quant Biol 76 2011 101 111 21960527
46 Harridge S.D. Ageing and local growth factors in muscle Scand J Med Sci Sports 13 1 2003 34 39 12535315
47 Conboy I.M. Conboy M.J. Wagers A.J. Girma E.R. Weissman I.L. Rando T.A. Rejuvenation of aged progenitor cells by exposure to a young systemic environment Nature 433 7027 2005 760 764 15716955
48 Bruunsgaard H. Skinhoj P. Pedersen A.N. Schroll M. Pedersen B.K. Ageing, tumour necrosis factor-alpha (TNF-alpha) and atherosclerosis Clin Exp Immunol 121 2 2000 255 260 10931139
49 Bruunsgaard H. Andersen-Ranberg K. Jeune B. Pedersen A.N. Skinhoj P. Pedersen B.K. A?high plasma concentration of TNF-alpha is associated with dementia in centenarians J?Gerontol A Biol Sci Med Sci 54 7 1999 M357 M364 10462168
50 Paik J.K. Chae J.S. Kang R. Kwon N. Lee S.H. Lee J.H. Effect of age on atherogenicity of LDL and inflammatory markers in healthy women Nutr Metabol Cardiovasc Dis 23 10 2013 967 972
51 Paolisso G. Rizzo M.R. Mazziotti G. Tagliamonte M.R. Gambardella A. Rotondi M. Advancing age and insulin resistance: role of plasma tumor necrosis factor-alpha Am J Physiol 275 2 1998 E294 E299 9688632
52 Pedersen M. Bruunsgaard H. Weis N. Hendel H.W. Andreassen B.U. Eldrup E. Circulating levels of TNF-alpha and IL-6-relation to truncal fat mass and muscle mass in healthy elderly individuals and in patients with type-2 diabetes Mech Ageing Dev 124 4 2003 495 502 12714258
53 Visser M. Pahor M. Taaffe D.R. Goodpaster B.H. Simonsick E.M. Newman A.B. Relationship of interleukin-6 and tumor necrosis factor-alpha with muscle mass and muscle strength in elderly men and women: the Health ABC Study J?Gerontol A Biol Sci Med Sci 57 5 2002 M326 M332 11983728
54 Wei J. Xu H. Davies J.L. Hemmings G.P. Increase of plasma IL-6 concentration with age in healthy subjects Life Sci 51 25 1992 1953 1956 1453878
55 Cohen H.J. Pieper C.F. Harris T. Rao K.M. Currie M.S. The association of plasma IL-6 levels with functional disability in community-dwelling elderly J?Gerontol A Biol Sci Med Sci 52 4 1997 M201 M208 9224431
56 Harris T.B. Ferrucci L. Tracy R.P. Corti M.C. Wacholder S. Ettinger W.H. Jr. Associations of elevated interleukin-6 and C-reactive protein levels with mortality in the elderly Am J Med 106 5 1999 506 512 10335721
57 Ferrucci L. Corsi A. Lauretani F. Bandinelli S. Bartali B. Taub D.D. The origins of age-related proinflammatory state Blood 105 6 2005 2294 2299 15572589
58 Schaap L.A. Pluijm S.M. Deeg D.J. Visser M. Inflammatory markers and loss of muscle mass (sarcopenia) and strength Am J Med 119 6 2006 526 e9-17
59 Puzianowska-Kuznicka M. Owczarz M. Wieczorowska-Tobis K. Nadrowski P. Chudek J. Slusarczyk P. Interleukin-6 and C-reactive protein, successful aging, and mortality: the PolSenior study Immun Ageing 13 2016 21 27274758
60 Chang S.F. Lin P.C. Yang R.S. Yang R.J. The preliminary effect of whole-body vibration intervention on improving the skeletal muscle mass index, physical fitness, and quality of life among older people with sarcopenia BMC Geriatr 18 1 2018 17 29343219
61 Egan B. Zierath J.R. Exercise metabolism and the molecular regulation of skeletal muscle adaptation Cell Metabol 17 2 2013 162 184
62 Pedersen B.K. Saltin B. Exercise as medicine - evidence for prescribing exercise as therapy in 26 different chronic diseases Scand J Med Sci Sports 25 Suppl 3 2015 1 72
63 Neubauer O. Sabapathy S. Ashton K.J. Desbrow B. Peake J.M. Lazarus R. Time course-dependent changes in the transcriptome of human skeletal muscle during recovery from endurance exercise: from inflammation to adaptive remodeling J?Appl Physiol (1985) 116 3 2014 274 287 24311745
64 Suzuki K. Peake J. Nosaka K. Okutsu M. Abbiss C.R. Surriano R. Changes in markers of muscle damage, inflammation and HSP70 after an Ironman Triathlon race Eur J Appl Physiol 98 6 2006 525 534 17031693
65 Nieman D.C. Henson D.A. Smith L.L. Utter A.C. Vinci D.M. Davis J.M. Cytokine changes after a marathon race J?Appl Physiol (1985) 91 1 2001 109 114 11408420
66 Dowling M.R. Kan A. Heinzel S. Marchingo J.M. Hodgkin P.D. Hawkins E.D. Regulatory T cells suppress effector T cell proliferation by limiting division destiny Front Immunol 9 2018 2461 30425712
67 Martinez F.O. Gordon S. The M1 and M2 paradigm of macrophage activation: time for reassessment F1000Prime Rep. 6 2014 13 24669294
68 Pillon N.J. Bilan P.J. Fink L.N. Klip A. Cross-talk between skeletal muscle and immune cells: muscle-derived mediators and metabolic implications Am J Physiol Endocrinol Metab 304 5 2013 E453 E465 23277185
69 Maynard C.L. Weaver C.T. Diversity in the contribution of interleukin-10 to T-cell-mediated immune regulation Immunol Rev 226 2008 219 233 19161427
70 Gleeson M. Bishop N.C. Stensel D.J. Lindley M.R. Mastana S.S. Nimmo M.A. The anti-inflammatory effects of exercise: mechanisms and implications for the prevention and treatment of disease Nat Rev Immunol 11 9 2011 607 615 21818123
71 Lancaster G.I. Febbraio M.A. The immunomodulating role of exercise in metabolic disease Trends Immunol 35 6 2014 262 269 24680647
72 Olfert I.M. Baum O. Hellsten Y. Egginton S. Advances and challenges in skeletal muscle angiogenesis Am J Physiol Heart Circ Physiol 310 3 2016 H326 H336 26608338
73 Landers-Ramos R.Q. Jenkins N.T. Spangenburg E.E. Hagberg J.M. Prior S.J. Circulating angiogenic and inflammatory cytokine responses to acute aerobic exercise in trained and sedentary young men Eur J Appl Physiol 114 7 2014 1377 1384 24643426
74 Kivela R. Kyrolainen H. Selanne H. Komi P.V. Kainulainen H. Vihko V. A?single bout of exercise with high mechanical loading induces the expression of Cyr61/CCN1 and CTGF/CCN2 in human skeletal muscle J?Appl Physiol 103 4 2007 1395 1401 17673559
75 Babapoor-Farrokhran S. Jee K. Puchner B. Hassan S.J. Xin X. Rodrigues M. Angiopoietin-like 4 is a potent angiogenic factor and a novel therapeutic target for patients with proliferative diabetic retinopathy Proc Natl Acad Sci U S A 112 23 2015 E3030 E3039 26039997
76 Mo C. Romero-Suarez S. Bonewald L. Johnson M. Brotto M. Prostaglandin E2: from clinical applications to its potential role in bone- muscle crosstalk and myogenic differentiation Recent Pat Biotechnol 6 3 2012 223 229 23092433
77 Juffer P. Jaspers R.T. Lips P. Bakker A.D. Klein-Nulend J. Expression of muscle anabolic and metabolic factors in mechanically loaded MLO-Y4 osteocytes Am J Physiol Endocrinol Metab 302 4 2012 E389 E395 22114022
78 Kaji H. Linkage between muscle and bone: common catabolic signals resulting in osteoporosis and sarcopenia Curr Opin Clin Nutr Metab Care 16 3 2013 272 277 23481148
79 Lanza I.R. Nair K.S. Muscle mitochondrial changes with aging and exercise Am J Clin Nutr 89 1 2009 467S-71S
80 Papanicolaou D.A. Ather S.N. Zhu H. Zhou Y. Lutkiewicz J. Scott B.B. A?phase IIA randomized, placebo-controlled clinical trial to study the efficacy and safety of the selective androgen receptor modulator (SARM), MK-0773 in female participants with sarcopenia J?Nutr Health Aging 17 6 2013 533 543 23732550
81 Bauer J.M. Verlaan S. Bautmans I. Brandt K. Donini L.M. Maggio M. Effects of a vitamin D and leucine-enriched whey protein nutritional supplement on measures of sarcopenia in older adults, the PROVIDE study: a randomized, double-blind, placebo-controlled trial J?Am Med Dir Assoc 16 9 2015 740 747 26170041
82 Cramer J.T. Cruz-Jentoft A.J. Landi F. Hickson M. Zamboni M. Pereira S.L. Impacts of high-protein oral nutritional supplements among malnourished men and women with sarcopenia: a multicenter, randomized, double-blinded, controlled trial J?Am Med Dir Assoc 17 11 2016 1044 1055 27780567
83 Kemmler W. Weissenfels A. Teschler M. Willert S. Bebenek M. Shojaa M. Whole-body electromyostimulation and protein supplementation favorably affect sarcopenic obesity in community-dwelling older men at risk: the randomized controlled FranSO study Clin Interv Aging 12 2017 1503 1513 28989278
84 Liao C.D. Tsauo J.Y. Lin L.F. Huang S.W. Ku J.W. Chou L.C. Effects of elastic resistance exercise on body composition and physical capacity in older women with sarcopenic obesity: a CONSORT-compliant prospective randomized controlled trial Medicine (Baltim) 96 23 2017 e7115
85 Chan D.C. Chang C.B. Han D.S. Hong C.H. Hwang J.S. Tsai K.S. Effects of exercise improves muscle strength and fat mass in patients with high fracture risk: a randomized control trial J?Formos Med Assoc 117 7 2018 572 582 29107439
86 Kemmler W. Bebenek M. Engelke K. von Stengel S. Impact of whole-body electromyostimulation on body composition in elderly women at risk for sarcopenia: the Training and ElectroStimulation Trial (TEST-III) Age (Dordr) 36 1 2014 395 406 23949160
87 Huang S.W. Ku J.W. Lin L.F. Liao C.D. Chou L.C. Liou T.H. Body composition influenced by progressive elastic band resistance exercise of sarcopenic obesity elderly women: a pilot randomized controlled trial Eur J Phys Rehabil Med 53 4 2017 556 563 28084062
88 Zdzieblik D. Oesser S. Baumstark M.W. Gollhofer A. Konig D. Collagen peptide supplementation in combination with resistance training improves body composition and increases muscle strength in elderly sarcopenic men: a randomised controlled trial Br J Nutr 114 8 2015 1237 1245 26353786
89 Konopka A.R. Laurin J.L. Musci R.V. Wolff C.A. Reid J.J. Biela L.M. Influence of Nrf2 activators on subcellular skeletal muscle protein and DNA synthesis rates after 6 weeks of milk protein feeding in older adults Geroscience 39 2 2017 175 186 28283797
90 Smith G.I. Julliand S. Reeds D.N. Sinacore D.R. Klein S. Mittendorfer B. Fish oil-derived n-3 PUFA therapy increases muscle mass and function in healthy older adults Am J Clin Nutr 102 1 2015 115 122 25994567
91 Yasuda T. Fukumura K. Tomaru T. Nakajima T. Thigh muscle size and vascular function after blood flow-restricted elastic band training in older women Oncotarget 7 23 2016 33595 33607 27244884
92 Gagliano-Juca T. Storer T.W. Pencina K.M. Travison T.G. Li Z. Huang G. Testosterone does not affect agrin cleavage in mobility-limited older men despite improvement in physical function Andrology 6 1 2018 29 36 28950424
93 Laksmi P.W. Setiati S. Tamin T.Z. Soewondo P. Rochmah W. Nafrialdi N. Effect of metformin on handgrip strength, gait speed, myostatin serum level, and health-related quality of life: a double blind randomized controlled trial among non-diabetic pre-frail elderly patients Acta Med Indones 49 2 2017 118 127 28790226
94 Candow D.G. Vogt E. Johannsmeyer S. Forbes S.C. Farthing J.P. Strategic creatine supplementation and resistance training in healthy older adults Appl Physiol Nutr Metabol 40 7 2015 689 694
95 Flodin L. Cederholm T. Saaf M. Samnegard E. Ekstrom W. Al-Ani A.N. Effects of protein-rich nutritional supplementation and bisphosphonates on body composition, handgrip strength and health-related quality of life after hip fracture: a 12-month randomized controlled study BMC Geriatr 15 2015 149 26572609
96 Da Boit M. Sibson R. Sivasubramaniam S. Meakin J.R. Greig C.A. Aspden R.M. Sex differences in the effect of fish-oil supplementation on the adaptive response to resistance exercise training in older people: a randomized controlled trial Am J Clin Nutr 105 1 2017 151 158 27852617
97 Trappe T.A. Ratchford S.M. Brower B.E. Liu S.Z. Lavin K.M. Carroll C.C. COX inhibitor influence on skeletal muscle fiber size and metabolic adaptations to resistance exercise in older adults J?Gerontol A Biol Sci Med Sci 71 10 2016 1289 1294 26817469
98 Strasser E.M. Hofmann M. Franzke B. Schober-Halper B. Oesen S. Jandrasits W. Strength training increases skeletal muscle quality but not muscle mass in old institutionalized adults: a randomized, multi-arm parallel and controlled intervention study Eur J Phys Rehabil Med 54 6 2018 921 933 29517189
99 Borack M.S. Reidy P.T. Husaini S.H. Markofski M.M. Deer R.R. Richison A.B. Soy-Dairy protein blend or whey protein isolate ingestion induces similar postexercise muscle mechanistic target of rapamycin complex 1 signaling and protein synthesis responses in older men J?Nutr 146 12 2016 2468 2475 27798330
100 Aleman-Mateo H. Carreon V.R. Macias L. Astiazaran-Garcia H. Gallegos-Aguilar A.C. Enriquez J.R. Nutrient-rich dairy proteins improve appendicular skeletal muscle mass and physical performance, and attenuate the loss of muscle strength in older men and women subjects: a single-blind randomized clinical trial Clin Interv Aging 9 2014 1517 1525 25258523
101 Stout J.R. Smith-Ryan A.E. Fukuda D.H. Kendall K.L. Moon J.R. Hoffman J.R. Effect of calcium beta-hydroxy-beta-methylbutyrate (CaHMB) with and without resistance training in men and women 65+yrs: a randomized, double-blind pilot trial Exp Gerontol 48 11 2013 1303 1310 23981904
102 Francis P. Mc Cormack W. Toomey C. Norton C. Saunders J. Kerin E. Twelve weeks' progressive resistance training combined with protein supplementation beyond habitual intakes increases upper leg lean tissue mass, muscle strength and extended gait speed in healthy older women Biogerontology 18 6 2017 881 891 27933408
103 Kemmler W. von Stengel S. Whole-body electromyostimulation as a means to impact muscle mass and abdominal body fat in lean, sedentary, older female adults: subanalysis of the TEST-III trial Clin Interv Aging 8 2013 1353 1364 24130433
104 Reid K.F. Martin K.I. Doros G. Clark D.J. Hau C. Patten C. Comparative effects of light or heavy resistance power training for improving lower extremity power and physical performance in mobility-limited older adults J?Gerontol A Biol Sci Med Sci 70 3 2015 374 380 25199912
105 Chale A. Cloutier G.J. Hau C. Phillips E.M. Dallal G.E. Fielding R.A. Efficacy of whey protein supplementation on resistance exercise-induced changes in lean mass, muscle strength, and physical function in mobility-limited older adults J?Gerontol A Biol Sci Med Sci 68 6 2013 682 690 23114462
106 Hofmann M. Schober-Halper B. Oesen S. Franzke B. Tschan H. Bachl N. Effects of elastic band resistance training and nutritional supplementation on muscle quality and circulating muscle growth and degradation factors of institutionalized elderly women: the Vienna Active Ageing Study (VAAS) Eur J Appl Physiol 116 5 2016 885 897 26931422
107 Fitts R.H. Peters J.R. Dillon E.L. Durham W.J. Sheffield-Moore M. Urban R.J. Weekly versus monthly testosterone administration on fast and slow skeletal muscle fibers in older adult males J?Clin Endocrinol Metab 100 2 2015 E223 E231 25387260
108 Hanson E.D. Srivatsan S.R. Agrawal S. Menon K.S. Delmonico M.J. Wang M.Q. Effects of strength training on physical function: influence of power, strength, and body composition J?Strength Condit Res 23 9 2009 2627 2637
109 Zakrzewski W. Dobrzynski M. Szymonowicz M. Rybak Z. Stem cells: past, present, and future Stem Cell Res Ther 10 1 2019 68 30808416
110 Bunout D. Barrera G. de la Maza P. Avendano M. Gattas V. Petermann M. The impact of nutritional supplementation and resistance training on the health functioning of free-living Chilean elders: results of 18 months of follow-up J?Nutr 131 9 2001 2441S-6S
111 Dillon E.L. Sheffield-Moore M. Paddon-Jones D. Gilkison C. Sanford A.P. Casperson S.L. Amino acid supplementation increases lean body mass, basal muscle protein synthesis, and insulin-like growth factor-I expression in older women J?Clin Endocrinol Metab 94 5 2009 1630 1637 19208731
112 Deutz N.E. Pereira S.L. Hays N.P. Oliver J.S. Edens N.K. Evans C.M. Effect of beta-hydroxy-beta-methylbutyrate (HMB) on lean body mass during 10 days of bed rest in older adults Clin Nutr 32 5 2013 704 712 23514626
113 Vukovich M.D. Stubbs N.B. Bohlken R.M. Body composition in 70-year-old adults responds to dietary beta-hydroxy-beta-methylbutyrate similarly to that of young adults J?Nutr 131 7 2001 2049 2052 11435528
114 Dupont J. Dedeyne L. Dalle S. Koppo K. Gielen E. The role of omega-3 in the prevention and treatment of sarcopenia Aging Clin Exp Res 31 6 2019 825 836 30784011
115 Hardee J.P. Lynch G.S. Current pharmacotherapies for sarcopenia Expet Opin Pharmacother 20 13 2019 1645 1657
116 Liguori I. Russo G. Aran L. Bulli G. Curcio F. Della-Morte D. Sarcopenia: assessment of disease burden and strategies to improve outcomes Clin Interv Aging 13 2018 913 927 29785098
117 Papadakis M.A. Grady D. Black D. Tierney M.J. Gooding G.A. Schambelan M. Growth hormone replacement in healthy older men improves body composition but not functional ability Ann Intern Med 124 8 1996 708 716 8633830
118 Yamanaka S. Induced pluripotent stem cells: past, present, and future Cell Stem Cell 10 6 2012 678 684 22704507
119 Liu X. Huang J. Chen T. Wang Y. Xin S. Li J. Yamanaka factors critically regulate the developmental signaling network in mouse embryonic stem cells Cell Res 18 12 2008 1177 1189 19030024
120 Trohatou O. Roubelakis M.G. Mesenchymal stem/stromal cells in regenerative medicine: past, present, and future Cell Reprogr 19 4 2017 217 224
121 Morales A.V. Mira H. Adult neural stem cells: born to last Front Cell Dev Biol 7 2019 96 31214589
122 Berberoglu M.A. Gallagher T.L. Morrow Z.T. Talbot J.C. Hromowyk K.J. Tenente I.M. Satellite-like cells contribute to pax7-dependent skeletal muscle repair in adult zebrafish Dev Biol 424 2 2017 162 180 28279710
123 Yang J. Liu H. Wang K. Li L. Yuan H. Liu X. Isolation, culture and biological characteristics of multipotent porcine skeletal muscle satellite cells Cell Tissue Bank 18 4 2017 513 525 28255772
124 Motohashi N. Asakura A. Muscle satellite cell heterogeneity and self-renewal Front Cell Dev Biol 2 2014 1 25364710
125 Zhuang Y. Li D. Fu J. Shi Q. Lu Y. Ju X. Comparison of biological properties of umbilical cord-derived mesenchymal stem cells from early and late passages: immunomodulatory ability is enhanced in aged cells Mol Med Rep 11 1 2015 166 174 25339265
126 Nagamura-Inoue T. He H. Umbilical cord-derived mesenchymal stem cells: their advantages and potential clinical utility World J Stem Cell 6 2 2014 195 202
127 Vahidinia Z. Azami Tameh A. Nejati M. Beyer C. Talaei S.A. Etehadi Moghadam S. The protective effect of bone marrow mesenchymal stem cells in a rat model of ischemic stroke via reducing the C-Jun N-terminal kinase expression Pathol Res Pract 215 9 2019 152519 31272760
128 Dabrowska S. Andrzejewska A. Lukomska B. Janowski M. Neuroinflammation as a target for treatment of stroke using mesenchymal stem cells and extracellular vesicles J?Neuroinflammation 16 1 2019 178 31514749
129 Chakari-Khiavi F. Dolati S. Chakari-Khiavi A. Abbaszadeh H. Aghebati-Maleki L. Pourlak T. Prospects for the application of mesenchymal stem cells in Alzheimer's disease treatment Life Sci 231 2019 116564 31202840
130 Reza-Zaldivar E.E. Hernandez-Sapiens M.A. Gutierrez-Mercado Y.K. Sandoval-Avila S. Gomez-Pinedo U. Marquez-Aguirre A.L. Mesenchymal stem cell-derived exosomes promote neurogenesis and cognitive function recovery in a mouse model of Alzheimer's disease Neural Regen Res 14 9 2019 1626 1634 31089063
131 Munoz M.F. Arguelles S. Medina R. Cano M. Ayala A. Adipose-derived stem cells decreased microglia activation and protected dopaminergic loss in rat lipopolysaccharide model J?Cell Physiol 234 8 2019 13762 13772 30637730
132 Park C.W. Kim K.S. Bae S. Son H.K. Myung P.K. Hong H.J. Cytokine secretion profiling of human mesenchymal stem cells by antibody array Int J Stem Cells 2 1 2009 59 68 24855521
133 Cunningham C.J. Redondo-Castro E. Allan S.M. The therapeutic potential of the mesenchymal stem cell secretome in ischaemic stroke J?Cerebr Blood Flow Metabol 38 8 2018 1276 1292
134 Mera P. Laue K. Ferron M. Confavreux C. Wei J. Galan-Diez M. Osteocalcin signaling in myofibers is necessary and sufficient for optimum adaptation to exercise Cell Metab 23 6 2016 Jun 14 1078 1092 10.1016/j.cmet.2016.05.004 27304508
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