최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기Critical reviews in oncology/hematology, v.163, 2021년, pp.103374 -
Addeo, Alfredo (Oncology Department, University Hospital of Geneva) , Friedlaender, Alex (Oncology Department, University Hospital of Geneva) , Banna, Giuseppe L. (Portsmouth Hospitals NHS Trust) , Weiss, Glen J. (MiRanostics Consulting)
Abstract Immune checkpoint inhibitors (ICIs) have revolutionized the landscape of therapeutic options for many cancers. These treatments have demonstrated improved efficacy and often a more favourable toxicity profile compared to standard cytotoxic chemotherapy. There are considerable differences a...
Expert Rev. Anticancer Ther. Alex 20 11 931 2020 10.1080/14737140.2020.1816173 Promising predictors of checkpoint inhibitor response in NSCLC
J. Exp. Clin. Cancer Res. Allegretti 37 1 47 2018 10.1186/s13046-018-0702-x Tearing down the walls: FDA approves next generation sequencing (NGS) assays for actionable cancer genomic aberrations
N. Engl. J. Med. André 383 23 2207 2020 10.1056/NEJMoa2017699 Pembrolizumab in microsatellite-instability-High advanced colorectal Cancer
Lancet Balar 389 10064 67 2017 10.1016/S0140-6736(16)32455-2 Atezolizumab as first-line treatment in cisplatin-ineligible patients with locally advanced and metastatic urothelial carcinoma: a single-arm, multicentre, phase 2 trial
Front. Med. (Lausanne) Banna 6 172 2019 The promise of digital biopsy for the prediction of tumor molecular features and clinical outcomes associated with immunotherapy
Clin. Transl. Oncol. Banna 22 11 2130 2020 10.1007/s12094-020-02337-3 Neutrophil-to-lymphocyte ratio and lactate dehydrogenase as biomarkers for urothelial cancer treated with immunotherapy
ESMO Open Banna 6 2 2021 10.1016/j.esmoop.2021.100078 The lung immuno-oncology prognostic score (LIPS-3): a prognostic classification of patients receiving first-line pembrolizumab for PD-L1 ≥ 50% advanced non-small-cell lung cancer
N. Engl. J. Med. Bellmunt 376 11 1015 2017 10.1056/NEJMoa1613683 Pembrolizumab as second-line therapy for advanced urothelial carcinoma
Oncoimmunology Boichard 6 3 2017 10.1080/2162402X.2017.1284719 High expression of PD-1 ligands is associated with kataegis mutational signature and APOBEC3 alterations
Oncoimmunology Boichard 8 3 2019 10.1080/2162402X.2018.1550341 APOBEC-related mutagenesis and neo-peptide hydrophobicity: implications for response to immunotherapy
Gastroenterology Boland 138 6 2073 2010 10.1053/j.gastro.2009.12.064 Microsatellite instability in colorectal Cancer
Am. J. Clin. Oncol. Buchbinder 39 1 98 2016 10.1097/COC.0000000000000239 CTLA-4 and PD-1 pathways: similarities, differences, and implications of their inhibition
ESMO Open Büttner 4 1 2019 10.1136/esmoopen-2018-000442 Implementing TMB measurement in clinical practice: considerations on assay requirements
Oncotarget Campesato 6 33 34221 2015 10.18632/oncotarget.5950 Comprehensive cancer-gene panels can be used to estimate mutational load and predict clinical benefit to PD-1 blockade in clinical practice
Clin. Cancer Res. Chabanon 22 17 4309 2016 10.1158/1078-0432.CCR-16-0903 Mutational landscape and sensitivity to immune checkpoint blockers
Genome Med. Chalmers 9 1 1 2017 10.1186/s13073-017-0424-2 Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden
Am. Soc. Clin. Oncol. Davis 2017 10.1200/JCO.2017.35.15_suppl.e23028 Comparison of tumor mutational burden (TMB) across tumor tissue and circulating tumor DNA (ctDNA)
J. Clin. Oncol. Devarakonda 36 30 2995 2018 10.1200/JCO.2018.78.1963 Tumor mutation burden as a biomarker in resected non-small-cell lung cancer
Appl. Transl. Genom. Endrullat 10 2 2016 Standardization and quality management in next-generation sequencing
Ann. Oncol. Fabrizio 28 v27 2017 10.1093/annonc/mdx363.018 Analytic validation of a next generation sequencing assay to identify tumor mutational burden from blood (bTMB) to support investigation of an anti-PD-L1 agent, atezolizumab, in a first line non-small cell lung cancer trial (BFAST)
J. Immunother. Cancer Fancello 7 1 1 2019 10.1186/s40425-019-0647-4 Tumor mutational burden quantification from targeted gene panels: major advancements and challenges
JAMA Oncol. Ferrara 4 11 1543 2018 10.1001/jamaoncol.2018.3676 Hyperprogressive disease in patients with advanced non-Small cell lung Cancer Treated with PD-1/PD-L1 inhibitors or with single-agent chemotherapy
Food 2020 Highlights of Prescribing Information: Keytruda
Food, U., Administration, D 2020 FDA Approves Pembrolizumab for Adults and Children With TMB-H Solid Tumors
Lung Cancer Manag. Friedlaender 8 3 2019 10.2217/lmt-2019-0009 Identifying successful biomarkers for patients with non-small-cell lung cancer
Nat. Med. Gandara 24 9 1441 2018 10.1038/s41591-018-0134-3 Blood-based tumor mutational burden as a predictor of clinical benefit in non-small-cell lung cancer patients treated with atezolizumab
Nat. Biotechnol. Gargis 30 11 1033 2012 10.1038/nbt.2403 Assuring the quality of next-generation sequencing in clinical laboratory practice
Genome Med. Garofalo 8 1 79 2016 10.1186/s13073-016-0333-9 The impact of tumor profiling approaches and genomic data strategies for cancer precision medicine
Mol. Cancer Ther. Goodman 16 11 2598 2017 10.1158/1535-7163.MCT-17-0386 Tumor mutational burden as an independent predictor of response to immunotherapy in diverse cancers
JAMA Oncol. Goodman 4 9 1237 2018 10.1001/jamaoncol.2018.1701 Prevalence of PDL1 amplification and preliminary response to immune checkpoint blockade in solid tumors
Cancer Immunol. Res. Goodman 7 10 1570 2019 10.1158/2326-6066.CIR-19-0149 Microsatellite-stable tumors with high mutational burden benefit from immunotherapy
Cancer Cell Hellmann 33 5 2018 10.1016/j.ccell.2018.03.018 Genomic features of response to combination immunotherapy in patients with advanced non-small-Cell lung Cancer
Cancer Immunol. Res. Johnson 4 11 959 2016 10.1158/2326-6066.CIR-16-0143 Targeted next generation sequencing identifies markers of response to PD-1 blockade
Nat. Commun. Kanchi 5 2014 10.1038/ncomms4156 Integrated analysis of germline and somatic variants in ovarian cancer
Sci. Rep. Kaur 9 1 1482 2019 10.1038/s41598-018-37574-8 Comparison of TCGA and GENIE genomic datasets for the detection of clinically actionable alterations in breast cancer
Clin. Cancer Res. Khagi 23 19 5729 2017 10.1158/1078-0432.CCR-17-1439 Hypermutated circulating tumor DNA: correlation with response to checkpoint inhibitor-based immunotherapy
Nucleic Acids Res. Kircher 40 1 2011 10.1093/nar/gkr771 Double indexing overcomes inaccuracies in multiplex sequencing on the Illumina platform
Klute 2020 Cobimetinib Plus Vemurafenib (C+ V) in Patients (Pts) With Colorectal Cancer (CRC) With BRAF V600E Mutations: Results From the TAPUR Study
Mol. Diagn. Ther. Kotrova 21 5 481 2017 10.1007/s40291-017-0277-9 Is next-generation sequencing the way to go for residual disease monitoring in acute lymphoblastic leukemia?
Cancer Cell Int. Li 20 2020 Microsatellite instability: a review of what the oncologist should know
N. Engl. J. Med. Lynch 348 10 919 2003 10.1056/NEJMra012242 Hereditary colorectal Cancer
Ann. Oncol. Marinelli 31 12 1746 2020 10.1016/j.annonc.2020.08.2105 KEAP1-driven co-mutations in lung adenocarcinoma unresponsive to immunotherapy despite high tumor mutational burden
Nature Matsushita 482 7385 400 2012 10.1038/nature10755 Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting
Ann. Oncol. McGrail 32 5 661 2021 10.1016/j.annonc.2021.02.006 High tumor mutation burden fails to predict immune checkpoint blockade response across all cancer types
Cancer Res. Mola 78 13 Supplement 2018 Abstract 2250: tumor mutational burden: guidelines for derivation and robustness of measurement
J. Thorac. Oncol. Müller 12 10 1503 2017 10.1016/j.jtho.2017.07.014 Concordance between comprehensive cancer genome profiling in plasma and tumor specimens
PLoS One Nelson 9 4 2014 10.1371/journal.pone.0094249 Analysis, optimization and verification of Illumina-generated 16S rRNA gene amplicon surveys
Gene Expr. Onuma 20 1 53 2020 10.3727/105221620X15880179864121 Immune checkpoint inhibitors in hepatocellular cancer: current understanding on mechanisms of resistance and biomarkers of response to treatment
Mol. Cancer Ther. Patel 14 4 847 2015 10.1158/1535-7163.MCT-14-0983 PD-L1 expression as a predictive biomarker in cancer immunotherapy
No. Annals of oncology : official journal of the European Society for Medical Oncology. Prasad 2020 10.1016/j.annonc.2020.07.001 The FDA approval of pembrolizumab for patients with TMB &10 mut/Mb: was it a wise decision?
N. Engl. J. Med. Reck 375 19 1823 2016 10.1056/NEJMoa1606774 Pembrolizumab versus chemotherapy for PD-L1-Positive non-Small-Cell lung Cancer
Eur. J. Cancer Reck 116 137 2019 10.1016/j.ejca.2019.05.008 Nivolumab plus ipilimumab versus chemotherapy as first-line treatment in advanced non-small-cell lung cancer with high tumour mutational burden: patient-reported outcomes results from the randomised, open-label, phase III CheckMate 227 trial
Mol. Cell Reuter 58 4 586 2015 10.1016/j.molcel.2015.05.004 High-throughput sequencing technologies
Cancers Rossi 12 5 1125 2020 10.3390/cancers12051125 Precision medicine for NSCLC in the era of immunotherapy: new biomarkers to select the most suitable treatment or the most suitable patient
N. Engl. J. Med. Rousseau 384 12 1168 2021 10.1056/NEJMc2031965 The Spectrum of benefit from checkpoint blockade in hypermutated tumors
Nat. Genet. Samstein 51 2 202 2019 10.1038/s41588-018-0312-8 Tumor mutational load predicts survival after immunotherapy across multiple cancer types
Annu. Rev. Immunol. Schumacher 37 173 2019 10.1146/annurev-immunol-042617-053402 Cancer neoantigens
Genet. Med. Schwarze 20 10 1122 2018 10.1038/gim.2017.247 Are whole-exome and whole-genome sequencing approaches cost-effective? A systematic review of the literature
Lancet Oncol. Seiwert 17 7 956 2016 10.1016/S1470-2045(16)30066-3 Safety and clinical activity of pembrolizumab for treatment of recurrent or metastatic squamous cell carcinoma of the head and neck (KEYNOTE-012): an open-label, multicentre, phase 1b trial
Ann. Oncol. Siravegna 30 10 1580 2019 10.1093/annonc/mdz227 How liquid biopsies can change clinical practice in oncology
Nat. Rev. Cancer Skoulidis 19 9 495 2019 10.1038/s41568-019-0179-8 Co-occurring genomic alterations in non-small-cell lung cancer biology and therapy
N. Engl. J. Med. Snyder 371 23 2189 2014 10.1056/NEJMoa1406498 Genetic basis for clinical response to CTLA-4 blockade in melanoma
Ann. Oncol. Subbiah 2020 10.1016/j.annonc.2020.07.002 The FDA approval of pembrolizumab for adult and pediatric patients with tumor mutational burden (TMB) ≥10: a decision centered on empowering patients and their physicians
Lancet Oncol. Turajlic 18 8 1009 2017 10.1016/S1470-2045(17)30516-8 Insertion-and-deletion-derived tumour-specific neoantigens and the immunogenic phenotype: a pan-cancer analysis
Nat. Commun. Valero 12 1 729 2021 10.1038/s41467-021-20935-9 Pretreatment neutrophil-to-lymphocyte ratio and mutational burden as biomarkers of tumor response to immune checkpoint inhibitors
JCO Precis Oncol Vokes 3 1 2019 Harmonization of tumor mutational burden quantification and association with response to immune checkpoint blockade in non-small-cell lung cancer
Genome Med. Wood 12 1 2020 10.1186/s13073-020-00729-2 Burden of tumor mutations, neoepitopes, and other variants are weak predictors of cancer immunotherapy response and overall survival
Ann. Transl. Med. Wu 7 22 2019 10.21037/atm.2019.10.116 Tumor mutational and indel burden: a systematic pan-cancer evaluation as prognostic biomarkers
Nat. Med. Zehir 23 6 703 2017 10.1038/nm.4333 Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients
*원문 PDF 파일 및 링크정보가 존재하지 않을 경우 KISTI DDS 시스템에서 제공하는 원문복사서비스를 사용할 수 있습니다.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.