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The mechanism of sitagliptin inhibition of colorectal cancer cell lines' metastatic functionalities 원문보기

IUBMB life, v.73 no.5, 2021년, pp.761 - 773  

Varela‐Calviño, Rubén (Department of Biochemistry and Molecular Biology University of Santiago de Compostela Santiago de Compostela Spain) ,  Rodríguez‐Quiroga, Marta (Institute of Research in Health and Innovation Universidade do Porto Porto Portugal) ,  Dias Carvalho, Patrícia (Institute of Research in Health and Innovation Universidade do Porto Porto Portugal) ,  Martins, Flavia (Institute of Research in Health and Innovation Universidade do Porto Porto Portugal) ,  Serra‐Roma, André (Institute of Research in Health and Innovation Universidade do Porto Porto Portugal) ,  Vázquez‐Iglesias, Lorena (Department of Biochemistry Immunology and Genetics, University of Vigo Vigo Spain) ,  Páez de la Cadena, María (Department of Biochemistry Immunology and Genetics, University of Vigo Vigo Spain) ,  Velho, Sérgia (Institute of Research in Health and Innovation Universidade do Porto Porto Portugal) ,  Cordero, Oscar J. (Department of Biochemistry and Molecular Biology University of Santiago de Compostela Santiago de Compostela Spain)

Abstract AI-Helper 아이콘AI-Helper

AbstractThe cell membrane glycoprotein CD26 with peptidase activity (DPP4) and/or its soluble CD26/DPP4 counterpart expression and/or activity are altered in several cancers. Its role in metastasis development was recently highlighted by the discovery of CD26+ cancer stem cell subsets and the fact t...

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