[논문]Differential Effects of Sound Intervention and Rest on Cardiovascular Parameters in Cancer Patients: A Randomized Cross-over Trial

Hohneck, Anna; Reyser, Christina; Merx, Kirsten; Weingä; rtner, Simone; Mavratzas, Athanasios; Schumacher, Gerhard; Linhuber, Christoph; Hofmann, Wolf-Karsten; Burkholder, Iris; Hofheinz, Ralf-Dieter

doi:10.1177/1534735421995239

Differential Effects of Sound Intervention and Rest on Cardiovascular Parameters in Cancer Patients: A Randomized Cross-over Trial 원문보기

Integrative cancer therapies, v.20, 2021년, pp.1534735421995239 -

Hohneck, Anna (University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany) , Reyser, Christina (University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany) , Merx, Kirsten (University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany) , Weingärtner, Simone (University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany) , Mavratzas, Athanasios (University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany) , Schumacher, Gerhard (inmediQ GmbH, Butzbach, Germany) , Linhuber, Christoph (Klangkoerper.de, Heidelberg, Germany) , Hofmann, Wolf-Karsten (University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany) , Burkholder, Iris (University of Applied Sciences of the Saarland, Saarbrucken, Germany) , Hofheinz, Ralf-Dieter (University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany)

Abstract ▼ AI-Helper

Background:Music therapy or sound interventions were shown to confer beneficial effects in patients with cancer for instance in terms of pain or fear relief and improvement of other patient reported outcomes. Cardiovascular parameters, especially heart rate variability (HRV) were found to have prognostic implications in cancer patients. In this trial we aimed to investigate the effects of a sound intervention on cardiovascular parameters compared to rest in patients with cancer.Methods and results:Using a randomized cross-over design, 52 patients (male 13, female 39) with cancer were recruited to receive both a 15-minute sound intervention and a 15-minute rest intervention within 4 weeks with at least a one-week blanking period. Cardiovascular parameters (among others HRV, aortic pulse wave velocity [PWV], augmentation index [Aix], aortic blood pressure [BP], heart rate [HR]) were assessed immediately before (pre) and after (post) the intervention had taken place. HRV (Root mean square of successive RR interval differences [RMSSD, ms]) significantly increased, during sound intervention (median RMSSD pre 24 [range 5-112] vs post 22 [range 9-141], P = .03). Likewise, median PWV, as a direct marker of arterial stiffness, was significantly reduced by sound intervention ([m/s] pre 8.5 [range 5.6-19.6] vs post 8.3 [range 5.6-15.6], P = .04). For both parameters no statistically significant change during rest was observed. HR was lowered by both, rest (P < .0001) and sound intervention (P = .02), with a more pronounced effect by rest. A significant increase in systolic aortic blood pressure was shown by rest ([mmHg] median 101 [range 78-150] vs post median 103 [range 71-152], P = .04) but not during sound intervention (P = .59), while rest intervention led to a decrease in resistance index (pre median 33 [range 13-92] vs post median 32 [11-84], P = .02).Conclusion:In comparison with rest, a single sound intervention in patients with cancer improved cardiovascular parameters commonly associated with increased stress levels. Studies with longer follow-up and multiple interventions are warranted.Trial Registration:ISRCTN registry 70947363.

주제어

참고문헌 (46)

1 Chase KM. Multicultural music therapy: a review of literature . Music Ther Perspect . 2003 ; 21 : 84 - 88 .

상세보기
2 Gutgsell KJ Schluchter M Margevicius S , et al . Music therapy reduces pain in palliative care patients: a randomized controlled trial . J Pain Symptom Manage . 2013 ; 45 : 822 - 831 . 23017609
3 Aalbers S Fusar-Poli L Freeman RE , et al . Music therapy for depression . Cochrane Database Syst Rev . 2017 ; 11 :CD004517.
4 Guetin S Portet F Picot M , et al . Effect of music therapy on anxiety and depression in patients with Alzheimer’s type dementia: randomised, controlled study . Dement Geriatr Cogn Disord . 2009 ; 28 : 36 - 46 . 19628939

상세보기
5 Zhang Y Cai J An L , et al . Does music therapy enhance behavioral and cognitive function in elderly dementia patients? A systematic review and meta-analysis . Ageing Res Rev . 2017 ; 35 : 1 - 11 . 28025173

상세보기
6 Li H-C Wang H-H Chou F-H Chen K-M. The effect of music therapy on cognitive functioning among older adults: a systematic review and meta-analysis . J Am Medl Dir Assoc . 2015 ; 16 : 71 - 77 .
7 Schwantes M McKinney C Hannibal N. Music therapy’s effects on levels of depression, anxiety, and social isolation in Mexican farmworkers living in the United States: a randomized controlled trial . Arts Psychother . 2014 ; 41 : 120 - 126 .

상세보기
8 Mathew D Sundar S Subramaniam E Parmar PN. Music therapy as group singing improves Geriatric Depression Scale score and loneliness in institutionalized geriatric adults with mild depression: a randomized controlled study . Int J Educ Psychol Res . 2017 ; 3 : 6 .
9 Hilliard RE. Music therapy in hospice and palliative care: a review of the empirical data . Evid Based Complement Alternat Med . 2005 ; 2 : 173 - 178 . 15937557

상세보기
10 Stanczyk MM. Music therapy in supportive cancer care . Rep Pract Oncol Radiother . 2011 ; 16 : 170 - 172 . 24376975
11 Stützlinger H Eisenmann A Laschkolnig A Mathis-Edenhofer S Pfabigan D RÄhrling I. Krebs: Kann eine begleitende Musiktherapie zu besseren Behandlungsergebnissen beitragen . Themen-Check Medizin, Vorläufiger Basisbericht HT17 . 2018 ; 2 : 185 .
12 Carrieri D Peccatori F Boniolo G. Supporting supportive care in cancer: the ethical importance of promoting a holistic conception of quality of life . Crit Rev Oncol Hematol . 2018 ; 131 : 90 - 95 . 30293711

상세보기
13 Reyes del Paso GA Langewitz W Mulder LJ Van Roon A Duschek S. The utility of low frequency heart rate variability as an index of sympathetic cardiac tone: a review with emphasis on a reanalysis of previous studies . Psychophysiology . 2013 ; 50 : 477 - 487 . 23445494

상세보기
14 Logan JG Barksdale DJ Carlson J Carlson BW Rowsey PJ. Psychological stress and arterial stiffness in Korean Americans . J Psychosom Res . 2012 ; 73 : 53 - 58 . 22691560

상세보기
15 Chuang C-Y Han W-R Li P-C Young S-T. Effects of music therapy on subjective sensations and heart rate variability in treated cancer survivors: a pilot study . Complement Ther Med . 2010 ; 18 : 224 - 226 . 21056846

상세보기
16 Zhou P Sui F Zhang A Wang F Li G. Music therapy on heart rate variability . Paper presented at: 2010 3rd International Conference on Biomedical Engineering and Informatics ; Yantai, China ; October 16-18, 2010 .
17 Sandler H Tamm S Fendel U Rose M Klapp B Bösel R. Positive emotional experience: induced by vibroacoustic stimulation using a body monochord in patients with psychosomatic disorders: is associated with an increase in EEG-theta and a decrease in EEG-alpha power . Brain Topogr . 2016 ; 29 : 524 - 538 . 26936595
18 Warth M Kessler J Koenig J Wormit AF Hillecke TK Bardenheuer HJ. Music therapy to promote psychological and physiological relaxation in palliative care patients: protocol of a randomized controlled trial . BMC Palliat Care . 2014 ; 13 : 60 . 25587239

상세보기
19 Gäbel C Garrido N Koenig J Hillecke TK Warth M. Effects of monochord music on heart rate variability and self-reports of relaxation in healthy adults . Complement Med Res . 2017 ; 24 : 97 - 103 . 28192781

상세보기
20 Baulmann J Weber T Mortensen K. Messmethoden der arteriellen Gefäßsteifigkeit . Journal für Hypertonie-Austrian J Hypertens . 2010 ; 14 : 18 - 24 .
21 Kraushaar LE Dressel A Maßmann A. Vascular robustness: the missing parameter in cardiovascular risk prediction . Prev Med Rep . 2018 ; 9 : 107 - 113 . 29527462
22 Massmann A Stemler J Fries P Kubale R Kraushaar LE Buecker A. Automated oscillometric blood pressure and pulse-wave acquisition for evaluation of vascular stiffness in atherosclerosis . Clin Res Cardiol . 2017 ; 106 : 514 - 524 . 28168512

상세보기
23 Van Bortel LM Laurent S Boutouyrie P , et al . Expert consensus document on the measurement of aortic stiffness in daily practice using carotid-femoral pulse wave velocity . J Hypertens . 2012 ; 30 : 445 - 448 . 22278144
24 Williams B Mancia G Spiering W , et al . 2018 ESC/ESH guidelines for the management of arterial hypertension: the Task Force for the management of arterial hypertension of the European Society of Cardiology (ESC) and the European Society of Hypertension (ESH) . Eur Heart J . 2018 ; 39 : 3021 - 3104 . 30165516
25 van den Berg ME Rijnbeek PR Niemeijer MN , et al . Normal values of corrected heart-rate variability in 10-second electrocardiograms for all ages . Front Physiol . 2018 ; 9 : 424 . 29755366

상세보기
26 O’Neal WT Chen LY Nazarian S Soliman EZ. Reference ranges for short-term heart rate variability measures in individuals free of cardiovascular disease: the Multi-Ethnic Study of Atherosclerosis (MESA) . J Electrocardiol . 2016 ; 49 : 686 - 690 . 27396499

상세보기
27 Nunan D Sandercock GR Brodie DA. A quantitative systematic review of normal values for short-term heart rate variability in healthy adults . Pacing Clin Electrophysiol . 2010 ; 33 : 1407 - 1417 . 20663071
28 Walsh D Nelson KA. Autonomic nervous system dysfunction in advanced cancer . Support Care Cancer . 2002 ; 10 : 523 - 528 . 12324806
29 Radin D Stone J Levine E , et al . Compassionate intention as a therapeutic intervention by partners of cancer patients: effects of distant intention on the patients’ autonomic nervous system . Explore . 2008 ; 4 : 235 - 243 . 18602616
30 Electrophysiology TFotESoCtNASoP . Heart rate variability: standards of measurement, physiological interpretation, and clinical use . Circulation . 1996 ; 93 : 1043 - 1065 . 8598068

상세보기
31 DeGiorgio CM Miller P Meymandi S , et al . RMSSD, a measure of vagus-mediated heart rate variability, is associated with risk factors for SUDEP: the SUDEP-7 Inventory . Epilepsy Behav . 2010 ; 19 : 78 - 81 . 20667792

상세보기
32 Pagani M Lombardi F Guzzetti S , et al . Power spectral density of heart rate variability as an index of sympatho-vagal interaction in normal and hypertensive subjects . J Hypertens . 1984 ; 2 : S383 .
33 Billman GE. The LF/HF ratio does not accurately measure cardiac sympatho-vagal balance . Front Physiol . 2013 ; 4 : 26 . 23431279

상세보기
34 Acharya UR Joseph KP Kannathal N Lim CM Suri JS. Heart rate variability: a review . Med Biol Eng Comput . 2006 ; 44 : 1031 - 1051 . 17111118

상세보기
35 Guo Y Koshy S Hui D , et al . Prognostic value of heart rate variability in patients with cancer . J Clin Neurophysiol . 2015 ; 32 : 516 - 520 . 26629761

상세보기
36 Zhou X Ma Z Zhang L , et al . Heart rate variability in the prediction of survival in patients with cancer: a systematic review and meta-analysis . J Psychosom Res . 2016 ; 89 : 20 - 25 . 27663106

상세보기
37 Raglio A Oasi O Gianotti M , et al . Effects of music therapy on psychological symptoms and heart rate variability in patients with dementia. A pilot study . Curr Aging Sci . 2010 ; 3 : 242 - 246 . 20735342
38 Faulkner S Jobling P March B Jiang CC Hondermarck H . Tumor neurobiology and the war of nerves in cancer . Cancer Discov . 2019 ; 9 : 702 - 710 . 30944117

상세보기
39 Ekbom A Lundegårdh G McLaughlin JK Nyrén O. Relation of vagotomy to subsequent risk of lung cancer: population based cohort study . BMJ . 1998 ; 316 : 518 . 9501714
40 Magnon C Hall SJ Lin J , et al . Autonomic nerve development contributes to prostate cancer progression . Science . 2013 ; 341 : 1236361 . 23846904

상세보기
41 Tibensky M Mravec B. Role of the parasympathetic nervous system in cancer initiation and progression . Clin Transl Oncol . Published online 8 8 , 2020 . doi: 10.1007/s12094-020-02465-w

상세보기
42 Wilkinson IB MacCallum H Flint L Cockcroft JR Newby DE Webb DJ. The influence of heart rate on augmentation index and central arterial pressure in humans . J Physiol . 2000 ; 525 ( Pt 1 ): 263 . 10811742
43 Ben-Shlomo Y Spears M Boustred C , et al . Aortic pulse wave velocity improves cardiovascular event prediction: an individual participant meta-analysis of prospective observational data from 17,635 subjects . J Am Coll Cardiol . 2014 ; 63 : 636 - 646 . 24239664

상세보기
44 Kong JO Koh SB Chang SJ , et al . Relationship between job stress and pulse wave velocity as a cardiovascular risk factor . Korean J Occup Environ Med . 2004 ; 16 : 450 - 458 .
45 Vlachopoulos C Kosmopoulou F Alexopoulos N Ioakeimidis N Siasos G Stefanadis C. Acute mental stress has a prolonged unfavorable effect on arterial stiffness and wave reflections . Psychosom Med . 2006 ; 68 : 231 - 237 . 16554388

상세보기
46 Vlachopoulos C Aggelakas A Ioakeimidis N , et al . Music decreases aortic stiffness and wave reflections . Atherosclerosis . 2015 ; 240 : 184 - 189 . 25796036

상세보기

표제어: PCR

동의어: Packet Collision Rate

용어 설명 출처 목록 (6)

용어 설명: PCR은 세균 특이성이 있는 primer를 이용하여 적은 수의 세균이 있을지라도 쉽게 검출할 수 있는 유용한 방법이며, 이를 이용하여 구강 내 치면세균막이나 타액에서 직접 세균을 검출할 수 있게 되었다[8].

내보내기 구분	파일저장 인쇄 메일전송
구성항목	기본정보 상세정보 관리번호, 논문명, 저널/프로시딩명, 저자 , 발행년, 권, 호, 시작페이지, 끝페이지, 발행기관 관리번호, 논문명, 대등논문명, 저자 , 저널/프로시딩명, 발행기관, 발행년, 발행언어, 권, 호, 시작페이지, 끝페이지, ISBN, ISSN, 주제분야, 키워드, 초록(한글), 초록(영문), 저자(소속기관)
저장형식	Text(ASCII format) Excel format RefWorks Direct Export RIS format (for Reference Manager, ProCite, EndNote), Scholar's Aids, Mendeley
메일정보	받는사람 (필수) @ 보내는사람 (선택) @ 제목 내용 KISTI 검색결과 이메일 서비스
안내	총 건의 자료가 검색되었습니다. 다운받으실 자료의 인덱스를 입력하세요. (1-10,000) 검색결과의 순서대로 최대 10,000건 까지 다운로드가 가능합니다. 데이타가 많을 경우 속도가 느려질 수 있습니다.(최대 2~3분 소요) 다운로드 파일은 UTF-8 형태로 저장됩니다. 파일의 내용이 제대로 보이지 않을실 때는 웹브라우저 상단의 보기 -> 인코딩 -> 자동선택 여부를 확인하십시오. ~ Text(ASCII format) Excel format

연합인증

Differential Effects of Sound Intervention and Rest on Cardiovascular Parameters in Cancer Patients: A Randomized Cross-over Trial 원문보기

Abstract ▼ AI-Helper

주제어

참고문헌 (46)

이 논문을 인용한 문헌

관련 콘텐츠

원문 보기

원문 URL 링크

오픈액세스(OA) 유형

연관된 기능

이 논문과 함께 이용한 콘텐츠

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

선택된 텍스트