[논문]Optical Coherence Tomography of Plaque Erosion : JACC Focus Seminar Part 2/3

Kolte, Dhaval; Yonetsu, Taishi; Ye, Jong Chul; Libby, Peter; Fuster, Valentin; Jang, Ik-Kyung

doi:10.1016/j.jacc.2021.07.030

[해외논문] Optical Coherence Tomography of Plaque Erosion : JACC Focus Seminar Part 2/3 원문보기

Journal of the American College of Cardiology, v.78 no.12, 2021년, pp.1266 - 1274

Kolte, Dhaval (Cardiology Division, Massachusetts General Hospital, Harvard Medical School) , Yonetsu, Taishi (Department of Interventional Cardiology, Tokyo Medical and Dental University) , Ye, Jong Chul (Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology) , Libby, Peter (Division of Cardiovascular Medicine, Brigham and Women’s Hospital, Harvard Medical School) , Fuster, Valentin (Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai) , Jang, Ik-Kyung (Cardiology Division, Massachusetts General Hospital, Harvard Medical School)

Abstract ▼ AI-Helper

Abstract Plaque erosion, a distinct histopathological and clinical entity, accounts for over 30% of acute coronary syndromes (ACS). Optical coherence tomography allows in vivo diagnosis of plaque erosion. Local flow perturbation with activation of Toll-like receptor 2 and CD8+ T cells and subsequent desquamation of endothelium and neutrophil extracellular trap formation contribute to mechanisms of plaque erosion. Compared with ACS patients with plaque rupture, those with plaque erosion are younger, have fewer traditional cardiovascular risk factors, have lower plaque burden, and are more likely to present with non–ST-segment elevation ACS. Early evidence suggests that in patients with ACS caused by plaque erosion, antithrombotic therapy without stenting may be a safe and effective option. Future randomized trials are needed to validate these findings. Clinical studies to develop noninvasive point-of-care biomarkers that distinguish plaque rupture from erosion, and to test novel therapies that target molecular pathways involved in plaque erosion are needed. Highlights Plaque erosion, a distinct histopathological and clinical entity, accounts for over 30% of cases of ACS. Available evidence suggests that in patients with ACS and plaque erosion, antithrombotic therapy without stenting may be a safe and effective therapeutic option, but confirmation will require evidence from randomized trials. Future research should address novel therapeutic strategies that target the molecular pathways involved in plaque erosion. Central Illustration [DISPLAY OMISSION]

Keyword

참고문헌 (44)

Circulation Virani 143 e254 2021 10.1161/CIR.0000000000000950 Heart Disease and Stroke Statistics-2021 Update: a report from the American Heart Association

상세보기
J Am Coll Cardiol Roth 76 2982 2020 10.1016/j.jacc.2020.11.010 Global Burden of cardiovascular diseases and risk factors, 1990-2019: update from the GBD 2019 study

상세보기
Circulation van der Wal 89 36 1994 10.1161/01.CIR.89.1.36 Site of intimal rupture or erosion of thrombosed coronary atherosclerotic plaques is characterized by an inflammatory process irrespective of the dominant plaque morphology

상세보기
Circulation Farb 93 1354 1996 10.1161/01.CIR.93.7.1354 Coronary plaque erosion without rupture into a lipid core. A frequent cause of coronary thrombosis in sudden coronary death

상세보기
J Am Coll Cardiol Jang 39 604 2002 10.1016/S0735-1097(01)01799-5 Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography: comparison with intravascular ultrasound

상세보기
Circulation Jang 111 1551 2005 10.1161/01.CIR.0000159354.43778.69 In vivo characterization of coronary atherosclerotic plaque by use of optical coherence tomography

상세보기
J Am Coll Cardiol Kubo 50 933 2007 10.1016/j.jacc.2007.04.082 Assessment of culprit lesion morphology in acute myocardial infarction: ability of optical coherence tomography compared with intravascular ultrasound and coronary angioscopy

상세보기
J Am Coll Cardiol Jia 62 1748 2013 10.1016/j.jacc.2013.05.071 In vivo diagnosis of plaque erosion and calcified nodule in patients with acute coronary syndrome by intravascular optical coherence tomography

상세보기
Arterioscler Thromb Vasc Biol Virmani 20 1262 2000 10.1161/01.ATV.20.5.1262 Lessons from sudden coronary death: a comprehensive morphological classification scheme for atherosclerotic lesions

상세보기
Circulation Falk 92 657 1995 10.1161/01.CIR.92.3.657 Coronary plaque disruption

상세보기
Eur Heart J Falk 34 719 2013 10.1093/eurheartj/ehs411 Update on acute coronary syndromes: the pathologists' view

상세보기
Arterioscler Thromb Vasc Biol Kolodgie 22 1642 2002 10.1161/01.ATV.0000034021.92658.4C Differential accumulation of proteoglycans and hyaluronan in culprit lesions: insights into plaque erosion

상세보기
Heart Sato 91 526 2005 10.1136/hrt.2004.034058 Proportion of fibrin and platelets differs in thrombi on ruptured and eroded coronary atherosclerotic plaques in humans

상세보기
Circ Res Libby 124 150 2019 10.1161/CIRCRESAHA.118.311098 Reassessing the mechanisms of acute coronary syndromes

상세보기
J Am Coll Cardiol Img Yamamoto 12 374 2019 10.1016/j.jcmg.2018.07.024 Endothelial shear stress and plaque erosion: a computational fluid dynamics and optical coherence tomography study

상세보기
Cardiovasc Res Thondapu 117 1974 2021 10.1093/cvr/cvaa251 High spatial endothelial shear stress gradient independently predicts site of acute coronary plaque rupture and erosion

상세보기
J Exp Med Mullick 205 373 2008 10.1084/jem.20071096 Increased endothelial expression of Toll-like receptor 2 at sites of disturbed blood flow exacerbates early atherogenic events

상세보기
Circ Res Franck 121 31 2017 10.1161/CIRCRESAHA.117.310694 Flow perturbation mediates neutrophil recruitment and potentiates endothelial injury via TLR2 in mice: implications for superficial erosion

상세보기
Eur Heart J Quillard 36 1394 2015 10.1093/eurheartj/ehv044 TLR2 and neutrophils potentiate endothelial stress, apoptosis and detachment: implications for superficial erosion

상세보기
Arterioscler Thromb Vasc Biol Sugiyama 24 1309 2004 10.1161/01.ATV.0000131784.50633.4f Hypochlorous acid, a macrophage product, induces endothelial apoptosis and tissue factor expression: involvement of myeloperoxidase-mediated oxidant in plaque erosion and thrombogenesis

상세보기
Eur Heart J Leistner 41 3549 2020 10.1093/eurheartj/ehaa703 Differential immunological signature at the culprit site distinguishes acute coronary syndrome with intact from acute coronary syndrome with ruptured fibrous cap: results from the prospective translational OPTICO-ACS study

상세보기
Circ Res Doring 120 736 2017 10.1161/CIRCRESAHA.116.309692 Neutrophil extracellular traps in atherosclerosis and atherothrombosis

상세보기
Proc Natl Acad Sci U S A Fuchs 107 15880 2010 10.1073/pnas.1005743107 Extracellular DNA traps promote thrombosis

상세보기
Circulation Yabushita 106 1640 2002 10.1161/01.CIR.0000029927.92825.F6 Characterization of human atherosclerosis by optical coherence tomography

상세보기
J Am Coll Cardiol Hu 63 1336 2014 10.1016/j.jacc.2013.11.025 Residual thrombus pattern in patients with ST-segment elevation myocardial infarction caused by plaque erosion versus plaque rupture after successful fibrinolysis: an optical coherence tomography study

상세보기
J Am Coll Cardiol Intv Higuma 8 1166 2015 10.1016/j.jcin.2015.02.026

상세보기
J Am Coll Cardiol Img Saia 8 566 2015 10.1016/j.jcmg.2015.01.018 Eroded versus ruptured plaques at the culprit site of STEMI: in vivo pathophysiological features and response to primary PCI

상세보기
Eur Heart J Niccoli 36 1377 2015 10.1093/eurheartj/ehv029 Plaque rupture and intact fibrous cap assessed by optical coherence tomography portend different outcomes in patients with acute coronary syndrome

상세보기
Int J Cardiol Yonetsu 203 766 2016 10.1016/j.ijcard.2015.11.030 Plaque morphologies and the clinical prognosis of acute coronary syndrome caused by lesions with intact fibrous cap diagnosed by optical coherence tomography

상세보기
EuroIntervention Kajander 12 716 2016 10.4244/EIJV12I6A116 Culprit plaque morphology in STEMI - an optical coherence tomography study: insights from the TOTAL-OCT substudy

상세보기
Korean Circ J Kwon 46 499 2016 10.4070/kcj.2016.46.4.499 Multimodality intravascular imaging assessment of plaque erosion versus plaque rupture in patients with acute coronary syndrome

상세보기
J Am Heart Assoc Hu 6 2017 Management and outcome of patients with acute coronary syndrome caused by plaque rupture versus plaque erosion: an intravascular optical coherence tomography study

상세보기
Eur Heart J Dai 39 2077 2018 10.1093/eurheartj/ehy101 In vivo predictors of plaque erosion in patients with ST-segment elevation myocardial infarction: a clinical, angiographical, and intravascular optical coherence tomography study

상세보기
J Am Heart Assoc Yamamoto 8 2019 Clinical and laboratory predictors for plaque erosion in patients with acute coronary syndromes

상세보기
Heart Arbustini 82 269 1999 10.1136/hrt.82.3.269 Plaque erosion is a major substrate for coronary thrombosis in acute myocardial infarction

상세보기
J Thromb Thrombolysis Kim 49 352 2020 10.1007/s11239-019-01969-9 Relative risk of plaque erosion among different age and sex groups in patients with acute coronary syndrome

상세보기
Am J Cardiol Russo 125 1757 2020 10.1016/j.amjcard.2020.03.017 Ethnic differences in the pathobiology of acute coronary syndromes between Asians and Whites

상세보기
Int J Cardiol Kim 288 12 2019 10.1016/j.ijcard.2019.03.039 Angiographic features of patients with coronary plaque erosion

상세보기
JAMA Cardiol Sugiyama 3 207 2018 10.1001/jamacardio.2017.5234 Nonculprit plaque characteristics in patients with acute coronary syndrome caused by plaque erosion vs plaque rupture: a 3-vessel optical coherence tomography study

상세보기
EuroIntervention Antoniadis 11 Suppl V V18 2015 10.4244/EIJV11SVA4 Impact of local flow haemodynamics on atherosclerosis in coronary artery bifurcations

상세보기
Nat Med Nesbitt 15 665 2009 10.1038/nm.1955 A shear gradient-dependent platelet aggregation mechanism drives thrombus formation

상세보기
Eur Heart J Jia 38 792 2017 Effective anti-thrombotic therapy without stenting: intravascular optical coherence tomography-based management in plaque erosion (the EROSION study)

상세보기
Circ Cardiovasc Interv Xing 10 2017 10.1161/CIRCINTERVENTIONS.117.005860 EROSION Study (Effective Anti-Thrombotic Therapy Without Stenting: Intravascular Optical Coherence Tomography-Based Management in Plaque Erosion): a 1-year follow-up report

상세보기
Cardiovasc Res Molinaro 2021 10.1093/cvr/cvab074 Targeted delivery of protein arginine deiminase-4 inhibitors to limit arterial intimal NETosis and preserve endothelial integrity

LOADING...

활용도 분석정보

상세보기

다운로드

내보내기

활용도 Top5 논문

해당 논문의 주제분야에서 활용도가 높은 상위 5개 콘텐츠를 보여줍니다.
더보기 버튼을 클릭하시면 더 많은 관련자료를 살펴볼 수 있습니다.

원문 보기

AccessON 원문보기

원문 URL 링크

DOI : 10.1016/j.jacc.2021.07.030 [무료]
Elsevier : 저널 > 논문 [무료]
American College of Cardiology : 저널
AccessON : 저널

*원문 PDF 파일 및 링크정보가 존재하지 않을 경우 KISTI DDS 시스템에서 제공하는 원문복사서비스를 사용할 수 있습니다.

ScienceON TREND Earth observations (Surface monitoring), 북극빙하

오픈액세스(OA) 유형

GOLD(Hybrid)

저자가 APC(Article Processing Charge)를 지불한 논문에 한하여 자유로운 이용이 가능한, hybrid 저널에 출판된 논문

연관된 기능

코센리포트

저작권 관리 안내

내보내기 메뉴

내보내기 구분

파일저장
인쇄
메일전송

구성항목

기본정보
상세정보

관리번호, 논문명, 저널/프로시딩명, 저자 , 발행년, 권, 호, 시작페이지, 끝페이지, 발행기관

저장형식

Text(ASCII format)
Excel format
RefWorks Direct Export
RIS format (for Reference Manager, ProCite, EndNote), Scholar's Aids, Mendeley

메일정보

받는사람 (필수): @
보내는사람 (선택): @
제목
내용: KISTI 검색결과 이메일 서비스

안내

총 건의 자료가 검색되었습니다.

다운받으실 자료의 인덱스를 입력하세요. (1-10,000)

검색결과의 순서대로 최대 10,000건 까지 다운로드가 가능합니다.

데이타가 많을 경우 속도가 느려질 수 있습니다.(최대 2~3분 소요)

다운로드 파일은 UTF-8 형태로 저장됩니다.
파일의 내용이 제대로 보이지 않을실 때는 웹브라우저 상단의 보기 -> 인코딩 -> 자동선택 여부를 확인하십시오.

Text(ASCII format)
Excel format

표제어: PCR

동의어: Packet Collision Rate

용어 설명 출처 목록 (6)

용어 설명: PCR은 세균 특이성이 있는 primer를 이용하여 적은 수의 세균이 있을지라도 쉽게 검출할 수 있는 유용한 방법이며, 이를 이용하여 구강 내 치면세균막이나 타액에서 직접 세균을 검출할 수 있게 되었다[8].

AI-Helper ※ AI-Helper는 을 사용합니다.

AI-Helper

안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

연합인증