[논문]Metabolomic Studies for the Evaluation of Toxicity Induced by Environmental Toxicants on Model Organisms

Kim, Hyung Min; Kang, Jong Seong

doi:10.3390/metabo11080485

[해외논문] Metabolomic Studies for the Evaluation of Toxicity Induced by Environmental Toxicants on Model Organisms 원문보기

Metabolites, v.11 no.8, 2021년, pp.485 -

Kim, Hyung Min , Kang, Jong Seong

Abstract ▼ AI-Helper

Environmental pollution causes significant toxicity to ecosystems. Thus, acquiring a deeper understanding of the concentration of environmental pollutants in ecosystems and, clarifying their potential toxicities is of great significance. Environmental metabolomics is a powerful technique in investigating the effects of pollutants on living organisms in the environment. In this review, we cover the different aspects of the environmental metabolomics approach, which allows the acquisition of reliable data. A step-by-step procedure from sample preparation to data interpretation is also discussed. Additionally, other factors, including model organisms and various types of emerging environmental toxicants are discussed. Moreover, we cover the considerations for successful environmental metabolomics as well as the identification of toxic effects based on data interpretation in combination with phenotype assays. Finally, the effects induced by various types of environmental toxicants in model organisms based on the application of environmental metabolomics are also discussed.

Keyword

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용어 설명: PCR은 세균 특이성이 있는 primer를 이용하여 적은 수의 세균이 있을지라도 쉽게 검출할 수 있는 유용한 방법이며, 이를 이용하여 구강 내 치면세균막이나 타액에서 직접 세균을 검출할 수 있게 되었다[8].

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