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[해외논문] Rufomycin Exhibits Dual Effects Against Mycobacterium abscessus Infection by Inducing Host Defense and Antimicrobial Activities 원문보기

Frontiers in microbiology, v.12, 2021년, pp.695024 -   

Park, Cho Rong (Department of Microbiology, Chungnam National University School of Medicine , Daejeon , South Korea) ,  Paik, Seungwha (Department of Microbiology, Chungnam National University School of Medicine , Daejeon , South Korea) ,  Kim, Young Jae (Department of Microbiology, Chungnam National University School of Medicine , Daejeon , South Korea) ,  Kim, Jin Kyung (Department of Microbiology, Chungnam National University School of Medicine , Daejeon , South Korea) ,  Jeon, Sang Min (Department of Microbiology, Chungnam National University School of Medicine , Daejeon , South Korea) ,  Lee, Sang-Hee (Center for Research Equipment, Korea Basic Science Institute , Cheongju , South Korea) ,  Whang, Jake (Korea Mycobacterium Resource Center & Basic Research Section, The Korean Institute of Tuberculosis , Cheongju , South Korea) ,  Cheng, Jinhua (Myongji Bioefficacy Research Center, Myongji Univers) ,  Suh, Joo-Won ,  Cao, Jin ,  Shetye, Gauri ,  Chen, Shao-Nong ,  McAlpine, James ,  Pauli, Guido F. ,  Franzblau, Scott ,  Cho, Sanghyun ,  Jo, Eun-Kyeong

Abstract ▼ AI-Helper 아이콘AI-Helper

Nontuberculous mycobacterial pulmonary infection is often aggravated due to antibiotic resistance issues. There is a need for development of new drugs inducing both host immune responses and antimicrobial activities. This study shows that the rufomycins 4/5/6/7 (Rufomycin 4–7), which targets ...

Keyword

#Mycobacterium abscessus   #rufomycin   #inflammation   #host immune defense   #antimicrobial activity  

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