$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

Trapa japonica Flerov Extract Prevents Obesity by Regulating Adipogenesis and Lipolysis in Differentiated 3T3-L1 Cells 원문보기

Applied sciences, v.12 no.1, 2022년, pp.290 -   

Park, Soo-Jeung (Beirne B. Cater Center for Immunology Research, University of Virginia, Charlottesville, VA 22901, USA) ,  Lee, Minhee (Department of Medical Nutrition, Kyung Hee University, Yongin 17104, Korea) ,  Kim, Ki-Young (Research Institute, Bio Port Korea Inc., Busan 46048, Korea) ,  Shin, Su (Research Institute, Bio Port Korea Inc., Busan 46048, Korea) ,  Choi, Min-Woo (Research Institute, Bio Port Korea Inc., Busan 46048, Korea) ,  Hong, Eun-Jin (Research Institute, Bio Port Korea Inc., Busan 46048, Korea) ,  Lee, Jeongmin (Clinical Nutrition Institute, Kyung Hee University, Seoul 02453, Korea)

Abstract AI-Helper 아이콘AI-Helper

Our study investigated that the anti-obesity effect of the Trapa japonica Flerov extract (TJ) in differentiated 3T3-L1 adipocytes. To this end, 3T3-L1 cells were treated with TJ during their differentiation period. On the last day of the cell culture, we tested intracellular cAMP, FA, glycerol relea...

참고문헌 (47)

  1. Lavie Obesity and atrial fibrillation prevalence, pathogenesis, and prognosis: Effects of weight loss and exercise J. Am. Coll. Cardiol. 2017 10.1016/j.jacc.2017.09.002 70 2022 

  2. Taylor The impact of obesity on quality of life Best Pract. Res. Clin. Endocrinol. Metab. 2013 10.1016/j.beem.2013.04.004 27 139 

  3. Nepali Chrysanthemum indicum inhibits adipogenesis and activates the AMPK pathway in high-fat-diet-induced obese mice Am. J. Chin. Med. 2018 10.1142/S0192415X18500076 46 119 

  4. Kanneganti Immunological complications of obesity Nut. Immunol. 2012 10.1038/ni.2343 13 707 

  5. 10.3390/ijms21134773 Deutsch, A., Feng, D., Pessin, J.E., and Shinoda, K. (2020). The impact of single-cell genomics on adipose tissue research. Int. J. Mol. Sci., 21. 

  6. Wolins OP9 mouse stromal cells rapidly differentiate into adipocytes. Characterization of a useful new model of adipogenesis J. Lipid Res. 2006 10.1194/jlr.D500037-JLR200 47 450 

  7. Jemai Colocynth (Citrullus colocynthis) seed extracts attenuate adipogenesis by down-regulating PPARγ/SREBP-1c and C/EBPα in 3T3-L1 cells Food. Biosci. 2020 10.1016/j.fbio.2019.100491 33 100491 

  8. White Transcriptional factors that promote formation of white adipose tissue Mol. Cell Endocrinol. 2010 10.1016/j.mce.2009.08.023 318 10 

  9. Oliveira Lack of platelet-activating factor receptor protects mice against diet-induced adipose inflammation and insulin-resistance despite fat pad expansion Obesity 2014 10.1002/oby.20142 22 663 

  10. Park Phenolics and neolignans isolated from the fruits of Juglans mandshurica, Maxim. And their effects on lipolysis in adipocytes Phytochemistry 2017 10.1016/j.phytochem.2017.01.019 137 87 

  11. Koster The contribution of hormone sensitive lipase to adipose tissue lipolysis and its regulation by insulin in periparturient dairy cows Sci. Rep. 2018 10.1038/s41598-018-31582-4 8 13378 

  12. Mei Down-regulation of cyclic-nucleotide phosphodiesterase 3B in 3T3-L1 adipocytes induced by tumor necrosis factor alpha and cAMP Biochem. J. 2000 10.1042/bj3460337 346 337 

  13. Carmen Signaling mechanisms regulating lipolysis Cell. Signal. 2006 10.1016/j.cellsig.2005.08.009 18 401 

  14. Suriyagoda Variation in growth and yield performance of seventeen water chestnut accessions (Trapa spp.) collected from Asia and Europe Plant. Prod. Sci. 2007 10.1626/pps.10.372 10 372 

  15. Kim Trapa japonica Flerov extract attenuates lipid accumulation through downregulation of adipogenic transcription factors in 3T3-L1 cells Am. J. Mol. Biol. 2015 10.4236/ajmb.2015.52004 5 32 

  16. Yasuda Inhibitory effects of polyphenols from water chestnut (Trapa japonica) husk on glycolytic enzymes and postprandial blood glucose elevation in mice Food. Chem. 2014 10.1016/j.foodchem.2014.05.083 165 42 

  17. Kim Antioxidant activity and protective effects of Trapa japonica pericarp extracts against tert-butylhydroperoxide-induced oxidative damage in chang cells Food. Chem. Toxicol. 2014 10.1016/j.fct.2013.11.018 64 49 

  18. Zhan Antitumor, antioxidant, and nitrite scavenging effects of chines water chestnut (Eleocharis dulcis) peel flavonoids J. Food. Sci. 2016 10.1111/1750-3841.13434 81 H2578 

  19. Park Emblica officinalis and Hordeum vulgare L. mixture regulates lipolytic activity in differentiatied 3T3-L1 cells J. Med. Food. 2021 10.1089/jmf.2020.4810 24 172 

  20. 10.3390/app10249078 Park, S.-J., Kim, D., Kim, J.-L., Park, M.-R., Kim, T.G., Kim, O.-K., and Nam, D.-E. (2002). Indian gooseberry and Barley sprout mixture inhibits aipogenesis and lipogenesis activity in 3T3-L1 adipocytes. Appl. Sci., 10. 

  21. Speliotes Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index Nat. Genet. 2010 10.1038/ng.686 42 937 

  22. Chu An update on physical health and economic consequences of overweight and obesity Diabetes Metab. Syndr. 2018 10.1016/j.dsx.2018.05.004 12 1095 

  23. Lee Inhibitory effects of green tea catechin on the lipid accumulation in 3T3-L1 adipocytes Phytother. Res. 2009 10.1002/ptr.2737 23 1088 

  24. Adesanya Effects of ethanolic extract of Irvingia gabonensis on the liver of progesterone induced obesity in female Swiss mice Res. J. Health Sci. 2019 7 302 

  25. Choi Who cares for nutrition information at a restaurant? Foo-related lifestyles and their association to nutrition information conscious behaviors Brit. Food J. 2016 10.1108/BFJ-09-2015-0303 118 1625 

  26. Bargale Mineralogical composition of water chestnut as compared to sweet potato Indian J. Nutr. Diet. 1987 24 78 

  27. Kang Water chestnut (Trapa japonica Flerov.) exerts inhibitory effect on postprandial glycemic response in rats and free radical scavenging activity in vitro Food. Sci. Biotechnol. 2019 18 808 

  28. Talcott Ellagic acid and flavonoid antioxidant content of muscadine wine and juice J. Agric. Food Chem. 2002 10.1021/jf011500u 50 3186 

  29. Xu DNA damaging activity of ellagic acid derivatives Bioorg. Med. Chem. 2003 10.1016/S0968-0896(02)00452-2 11 1593 

  30. Zeng Green tea consumption and risk of pancreatic cancer: A meta-analysis Nutrients 2014 10.3390/nu6114640 6 4640 

  31. Zhu Combination therapy with catechins and caffeine inhibits fat accumulation in 3T3-L1 cells Exp. Ther. Med. 2017 10.3892/etm.2016.3975 13 688 

  32. Lee Root extracts of adenophora triphylla var. japonica improve obesity in 3T3-L1 adipocytes and high-fat diet-induced obese mice Asian Pac. J. Trop. Med. 2015 10.1016/j.apjtm.2015.10.011 8 898 

  33. Fox Regulation of cyclin D1 and wnt10b gene expression by cAMP-responsive element-binding protein during early adipogenesis involves differential promotor methylation J. Biol. Chem. 2008 10.1074/jbc.M806423200 283 35096 

  34. Lowell Regulation of PPAR gamma gene expression by nutrition and obesity in rodents J. Clin. Investig. 1996 10.1172/JCI118703 97 2553 

  35. Yi Identification of the potential key genes for adipogenesis from human mesenchymal stem cells by RNA-Seq J. Cell Physiol. 2019 10.1002/jcp.28621 234 20217 

  36. Li Suppression of adipocyte differentiation and lipid accumulation by stearidonic acid (SDA) in 3T3-L1 cells Lipid Health Dis. 2017 10.1186/s12944-017-0574-7 16 181 

  37. Lee Nobiletin improves obesity and insulin resistance in high-fat diet-induced obese mice J. Nutr. Biochem. 2014 10.1016/j.jnutbio.2012.03.014 24 156 

  38. Browning Molecular mediators of hepatic steatosis and liver injury J. Clin. Investig. 2004 10.1172/JCI200422422 114 147 

  39. Foretz ADD1/SREBP-1c is required in the activation of hepatic lipogenic geneexpression by glucose Mol. Cell Biol. 1999 10.1128/MCB.19.5.3760 19 3760 

  40. Molenear All three promoters of the acetyl-coenzyme A-carboxylase ALPA-encoding gene are expressed in mammary epithelial cells of ruminants J. Histochem. Cytochem. 2003 10.1177/002215540305100811 51 1073 

  41. Smith The animal fatty acid synthase: One gen, one polypeptide, seven enzymes FASEB J. 1994 10.1096/fasebj.8.15.8001737 8 1248 

  42. Jang Berberine activates AMPK to suppress proteolytic processing, nuclear translocation and target DNA binding of SREBP-1c in 3T3-L1 adipocytes Mol. Med. Rep. 2017 10.3892/mmr.2017.6513 15 4139 

  43. Choi Green coffee bean extract improves obesity by decreasing body fat in high-fat diet induced obese mice Asian Pac. J. Trop. Med. 2016 10.1016/j.apjtm.2016.05.017 9 635 

  44. Blomquist Decreased lipogenesis-promoting factors in adiose tissue in postmenopausal women with overweight on a Paleolithic-type diet Eur. J. Nutr. 2018 10.1007/s00394-017-1558-0 57 2877 

  45. Xavier Therapeutic potential of phosphodiesterase inhibitors for endothelial dysfunction-related diseases Curr. Phar. Des. 2020 10.2174/1381612826666200403172736 26 3633 

  46. Jiang Qian, L.; Chen, M. Astragaloside IV attenuates lipolysis and improves insulin resistance induced by TNFalpha in 3T3-L1 adipocytes Phytother. Res. 2008 10.1002/ptr.2434 22 1434 

  47. Sztalryd The perilipin family of lipid droplet proteins: Gatekeepers of intracellular lipolysis Biochim. Biophys. Acta Mol. Cell Biol. Lipids 2017 10.1016/j.bbalip.2017.07.009 1862 1221 

섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로