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Particulate matter (PM10) destabilizes mitotic spindle through downregulation of SETD2 in A549 lung cancer cells

Chemosphere, v.295, 2022년, pp.133900 -   

Santibáñez-Andrade, Miguel (Subdirecció) ,  Sánchez-Pérez, Yesennia (n de Investigació) ,  Chirino, Yolanda I. (n Bá) ,  Morales-Bárcenas, Rocío (sica, Instituto Nacional de Cancerologí) ,  Quintana-Belmares, Raúl (a) ,  García-Cuellar, Claudia M. (Subdirecció)

Abstract AI-Helper 아이콘AI-Helper

Abstract Air pollution represents an environmental problem, impacting negatively in human health. Particulate matter of 10 μm or less in diameter (PM10) is related to pulmonary diseases, including lung cancer. Mitotic spindle is made up by chromosome-microtubule (MT) interactions, where SETD2 pl...

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