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Cancer letters, v.278 no.2, 2009년, pp.192 - 200
Sánchez-Pérez, Yesennia (Instituto Nacional de Cancerologí) , Chirino, Yolanda I. (a (INCan), Subdirecció) , Osornio-Vargas, Álvaro R. (n de Investigació) , Morales-Bárcenas, Rocío (n Bá) , Gutiérrez-Ruíz, Concepción (sica, San Fernando No. 22, Tlalpan, 14080 Mexico, DF, Mexico) , Vázquez-López, Inés (Instituto Nacional de Cancerologí) , García-Cuellar, Claudia M. (a (INCan), Subdirecció)
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Abstract We describe the events triggered by a sub-lethal concentration of airborne particulate matter (PM10) in A549 cells, which include the formation DNA double-strand breaks, γH2A.X generation, and 53BP1 recruitment. To protect the genome, cells activated ATM/ATR/Chk1/Chk2/p53 pathway but...
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