$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

Lysosome‐Targeted and Fluorescence‐Turned “On” Cytotoxicity Induced by Alkaline Phosphatase‐Triggered Self‐Assembly

Advanced healthcare materials, v.11 no.1, 2022년, pp.2101346 -   

Wu, Chengfan (Hefei National Laboratory of Physical Sciences at Microscale Department of Chemistry University of Science and Technology of China 96 Jinzhai Road Hefei Anhui 230026 China) ,  Wang, Chenchen (Hefei National Laboratory of Physical Sciences at Microscale Department of Chemistry University of Science and Technology of China 96 Jinzhai Road Hefei Anhui 230026 China) ,  Zhang, Tong (School of Life Sciences University of Science and Technology of China 443 Huangshan Road Hefei Anhui 230027 China) ,  Gao, Ge (State Key Laboratory of Bioelectronics School of Biological Science and Medical Engineering Southeast University 2 Sipailou Road Nanjing 210096 China) ,  Wei, Mengxing (Hefei National Laboratory of Physical Sciences at Microscale Department of Chemistry University of Science and Technology of China 96 Jinzhai Road Hefei Anhui 230026 China) ,  Chen, Yinglu (Hefei National Laboratory of Physical Sciences at Microscale Department of Chemistry University of Science and Technology of China 96 Jinzhai Road Hefei Anhui 230026 China) ,  Li, Xiaoyan (Analysis Center Nanjing Medical Univ) ,  Wang, Fuqiang ,  Liang, Gaolin

Abstract AI-Helper 아이콘AI-Helper

AbstractSelectively inducing lysosomal membrane permeabilization (LMP) is a promising strategy for cancer therapy. But integrating alkaline phosphatase (ALP)‐instructed self‐assembly and lysosome‐targeting to induce LMP for selective killing of cancer cells was not reported. Her...

참고문헌 (50)

  1. Siegel, Rebecca L., Miller, Kimberly D., Jemal, Ahmedin. Cancer statistics, 2017. CA: A Cancer Journal for Clinicians, vol.67, no.1, 7-30.

  2. Siegel, Rebecca L., Miller, Kimberly D., Jemal, Ahmedin. Cancer statistics, 2018. CA: A Cancer Journal for Clinicians, vol.68, no.1, 7-30.

  3. Keereweer, Stijn, Van Driel, Pieter B.A.A., Snoeks, Thomas J.A., Kerrebijn, Jeroen D.F., Baatenburg de Jong, Robert J., Vahrmeijer, Alexander L., Sterenborg, Henricus J.C.M., Löwik, Clemens W.G.M.. Optical Image-Guided Cancer Surgery: Challenges and Limitations. Clinical Cancer research : an official journal of the American Association for Cancer Research, vol.19, no.14, 3745-3754.

  4. Nori, Aparna, Kopeček, Jindřich. Intracellular targeting of polymer-bound drugs for cancer chemotherapy. Advanced drug delivery reviews, vol.57, no.4, 609-636.

  5. Huang, Qian, Li, Fang, Liu, Xinjian, Li, Wenrong, Shi, Wei, Liu, Fei-Fei, O'Sullivan, Brian, He, Zhimin, Peng, Yuanlin, Tan, Aik-Choon, Zhou, Ling, Shen, Jingping, Han, Gangwen, Wang, Xiao-Jing, Thorburn, Jackie, Thorburn, Andrew, Jimeno, Antonio, Raben, David, Bedford, Joel S, Li, Chuan-Yuan. Caspase 3??mediated stimulation of tumor cell repopulation during cancer radiotherapy. Nature medicine, vol.17, no.7, 860-866.

  6. DeVita Jr., Vincent T., Chu, Edward. A History of Cancer Chemotherapy. Cancer research : the official organ of the American Association for Cancer Research, Inc, vol.68, no.21, 8643-8653.

  7. Hanahan, Douglas, Weinberg, Robert A.. Hallmarks of Cancer: The Next Generation. Cell, vol.144, no.5, 646-674.

  8. Stommel, Jayne M., Kimmelman, Alec C., Ying, Haoqiang, Nabioullin, Roustem, Ponugoti, Aditya H., Wiedemeyer, Ruprecht, Stegh, Alexander H., Bradner, James E., Ligon, Keith L., Brennan, Cameron, Chin, Lynda, DePinho, Ronald A.. Coactivation of Receptor Tyrosine Kinases Affects the Response of Tumor Cells to Targeted Therapies. Science, vol.318, no.5848, 287-290.

  9. Thornberry, Nancy A., Rano, Thomas A., Peterson, Erin P., Rasper, Dita M., Timkey, Tracy, Garcia-Calvo, Margarita, Houtzager, Vicky M., Nordstrom, Penny A., Roy, Sophie, Vaillancourt, John P., Chapman, Kevin T., Nicholson, Donald W.. A Combinatorial Approach Defines Specificities of Members of the Caspase Family and Granzyme B. The Journal of biological chemistry, vol.272, no.29, 17907-17911.

  10. Negrini, Simona, Gorgoulis, Vassilis G., Halazonetis, Thanos D.. Genomic instability — an evolving hallmark of cancer. Nature reviews. Molecular cell biology, vol.11, no.3, 220-228.

  11. Patel, Anoop P., Tirosh, Itay, Trombetta, John J., Shalek, Alex K., Gillespie, Shawn M., Wakimoto, Hiroaki, Cahill, Daniel P., Nahed, Brian V., Curry, William T., Martuza, Robert L., Louis, David N., Rozenblatt-Rosen, Orit, Suvà, Mario L., Regev, Aviv, Bernstein, Bradley E.. Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma. Science, vol.344, no.6190, 1396-1401.

  12. Mantovani, Alberto, Allavena, Paola, Sica, Antonio, Balkwill, Frances. Cancer-related inflammation. Nature, vol.454, no.7203, 436-444.

  13. Pouponneau, P., Leroux, J.C., Soulez, G., Gaboury, L., Martel, S.. Co-encapsulation of magnetic nanoparticles and doxorubicin into biodegradable microcarriers for deep tissue targeting by vascular MRI navigation. Biomaterials, vol.32, no.13, 3481-3486.

  14. Shi, Xiangyang, Wang, Suhe, Meshinchi, Sasha, Van Antwerp, Mary E., Bi, Xiangdong, Lee, Inhan, Baker Jr., James R.. Dendrimer-Entrapped Gold Nanoparticles as a Platform for Cancer-Cell Targeting and Imaging. Small, vol.3, no.7, 1245-1252.

  15. Nayak, Satish, Lee, Hsienming, Chmielewski, Jean, Lyon, L. Andrew. Folate-Mediated Cell Targeting and Cytotoxicity Using Thermoresponsive Microgels. Journal of the American Chemical Society, vol.126, no.33, 10258-10259.

  16. Rajendran, Lawrence, Knölker, Hans-Joachim, Simons, Kai. Subcellular targeting strategies for drug design and delivery. Nature reviews. Drug discovery, vol.9, no.1, 29-42.

  17. Feng, Zhaoqianqi, Wang, Huaimin, Wang, Shiyu, Zhang, Qiang, Zhang, Xixiang, Rodal, Avital A., Xu, Bing. Enzymatic Assemblies Disrupt the Membrane and Target Endoplasmic Reticulum for Selective Cancer Cell Death. Journal of the American Chemical Society, vol.140, no.30, 9566-9573.

  18. Biswas, S., Torchilin, V.P.. Nanopreparations for organelle-specific delivery in cancer. Advanced drug delivery reviews, vol.66, 26-41.

  19. Yuan, Peiyan, Mao, Xin, Wu, Xiaofeng, Liew, Si Si, Li, Lin, Yao, Shao Q.. Mitochondria‐Targeting, Intracellular Delivery of Native Proteins Using Biodegradable Silica Nanoparticles. Angewandte Chemie. international edition, vol.58, no.23, 7657-7661.

  20. Healy, S.J.M., Gorman, A.M., Mousavi-Shafaei, P., Gupta, S., Samali, A.. Targeting the endoplasmic reticulum-stress response as an anticancer strategy. European journal of pharmacology, vol.625, no.1, 234-246.

  21. PanThese authors contributed equally to this article., Limin, Liu, Jianan, Shi, Jianlin. Cancer cell nucleus-targeting nanocomposites for advanced tumor therapeutics. Chemical Society reviews, vol.47, no.18, 6930-6946.

  22. Dielschneider, Rebecca F., Henson, Elizabeth S., Gibson, Spencer B.. Lysosomes as Oxidative Targets for Cancer Therapy. Oxidative medicine and cellular longevity, vol.2017, 3749157-.

  23. Wan, Qiongqiong, Chen, Suming, Shi, Wen, Li, Lihong, Ma, Huimin. Lysosomal pH Rise during Heat Shock Monitored by a Lysosome‐Targeting Near‐Infrared Ratiometric Fluorescent Probe. Angewandte Chemie. international edition, vol.53, no.41, 10916-10920.

  24. Settembre, Carmine, Fraldi, Alessandro, Medina, Diego L., Ballabio, Andrea. Signals from the lysosome: a control centre for cellular clearance and energy metabolism. Nature reviews. Molecular cell biology, vol.14, no.5, 283-296.

  25. Wu, Wei, Luo, Li, Wang, Yi, Wu, Qi, Dai, Han-Bin, Li, Jian-Shu, Durkan, Colm, Wang, Nan, Wang, Gui-Xue. Endogenous pH-responsive nanoparticles with programmable size changes for targeted tumor therapy and imaging applications. Theranostics, vol.8, no.11, 3038-3058.

  26. Thekkedath, Ritesh, Koshkaryev, Alexander, Torchilin, Vladimir P. Lysosome-Targeted Octadecyl-Rhodamine B-Liposomes Enhance Lysosomal Accumulation of Glucocerebrosidase in Gaucher‘S Cells In Vitro. Nanomedicine, vol.8, no.7, 1055-1065.

  27. Serrano-Puebla, Ana, Boya, Patricia. Lysosomal membrane permeabilization as a cell death mechanism in cancer cells. Biochemical Society transactions, vol.46, no.2, 207-215.

  28. Borkowska, Magdalena, Siek, Marta, Kolygina, Diana V., Sobolev, Yaroslav I., Lach, Slawomir, Kumar, Sumit, Cho, Yoon-Kyoung, Kandere-Grzybowska, Kristiana, Grzybowski, Bartosz A.. Targeted crystallization of mixed-charge nanoparticles in lysosomes induces selective death of cancer cells. Nature nanotechnology, vol.15, no.4, 331-341.

  29. Wang, Fengjuan, Gómez‐Sintes, Raquel, Boya, Patricia. Lysosomal membrane permeabilization and cell death. Traffic, vol.19, no.12, 918-931.

  30. Boya, P, Kroemer, G. Lysosomal membrane permeabilization in cell death. Oncogene, vol.27, no.50, 6434-6451.

  31. Serrano‐Puebla, Ana, Boya, Patricia. Lysosomal membrane permeabilization in cell death: new evidence and implications for health and disease. Annals of the New York Academy of Sciences, vol.1371, no.1, 30-44.

  32. Zhou, Jie, Xu, Bing. Enzyme-Instructed Self-Assembly: A Multistep Process for Potential Cancer Therapy. Bioconjugate chemistry, vol.26, no.6, 987-999.

  33. Feng, Zhaoqianqi, Wang, Huaimin, Du, Xuewen, Shi, Junfeng, Li, Jie, Xu, Bing. Minimal C-terminal modification boosts peptide self-assembling ability for necroptosis of cancer cells. Chemical communications : Chem comm, vol.52, no.37, 6332-6335.

  34. Tanaka, Akiko, Fukuoka, Yuki, Morimoto, Yuka, Honjo, Takafumi, Koda, Daisuke, Goto, Masahiro, Maruyama, Tatsuo. Cancer Cell Death Induced by the Intracellular Self-Assembly of an Enzyme-Responsive Supramolecular Gelator. Journal of the American Chemical Society, vol.137, no.2, 770-775.

  35. Pires, Ricardo A., Abul-Haija, Yousef M., Costa, Diana S., Novoa-Carballal, Ramon, Reis, Rui L., Ulijn, Rein V., Pashkuleva, Iva. Controlling Cancer Cell Fate Using Localized Biocatalytic Self-Assembly of an Aromatic Carbohydrate Amphiphile. Journal of the American Chemical Society, vol.137, no.2, 576-579.

  36. Wang, Huaimin, Feng, Zhaoqianqi, Wu, Dongdong, Fritzsching, Keith J., Rigney, Mike, Zhou, Jie, Jiang, Yujie, Schmidt-Rohr, Klaus, Xu, Bing. Enzyme-Regulated Supramolecular Assemblies of Cholesterol Conjugates against Drug-Resistant Ovarian Cancer Cells. Journal of the American Chemical Society, vol.138, no.34, 10758-10761.

  37. Zhan, Jie, Cai, Yanbin, He, Shuangshuang, Wang, Ling, Yang, Zhimou. Tandem Molecular Self‐Assembly in Liver Cancer Cells. Angewandte Chemie. international edition, vol.57, no.7, 1813-1816.

  38. FISHMAN, WILLIAM H., INGLIS, NORMA R., GREEN, SIDNEY, ANSTISS, CLAIRE L., GOSH, NIMAI K., REIF, ARNOLD E., RUSTIGIAN, ROBERT, KRANT, MELVIN J., STOLBACH, LEO L.. Immunology and Biochemistry of Regan Isoenzyme of Alkaline Phosphatase in Human Cancer. Nature, vol.219, no.5155, 697-699.

  39. Zhou, Jie, Du, Xuewen, Xu, Bing. Regulating the Rate of Molecular Self‐Assembly for Targeting Cancer Cells. Angewandte Chemie. international edition, vol.55, no.19, 5770-5775.

  40. Wu, Chengfan, Zhang, Rui, Du, Wei, Cheng, Liang, Liang, Gaolin. Alkaline Phosphatase-Triggered Self-Assembly of Near-Infrared Nanoparticles for the Enhanced Photoacoustic Imaging of Tumors. Nano letters : a journal dedicated to nanoscience and nanotechnology, vol.18, no.12, 7749-7754.

  41. Wang, Huaimin, Feng, Zhaoqianqi, Wang, Youzhi, Zhou, Rong, Yang, Zhimou, Xu, Bing. Integrating Enzymatic Self-Assembly and Mitochondria Targeting for Selectively Killing Cancer Cells without Acquired Drug Resistance. Journal of the American Chemical Society, vol.138, no.49, 16046-16055.

  42. Jeena, M. T., Palanikumar, L., Go, Eun Min, Kim, Inhye, Kang, Myoung Gyun, Lee, Seonik, Park, Sooham, Choi, Huyeon, Kim, Chaekyu, Jin, Seon-Mi, Bae, Sung Chul, Rhee, Hyun Woo, Lee, Eunji, Kwak, Sang Kyu, Ryu, Ja-Hyoung. Mitochondria localization induced self-assembly of peptide amphiphiles for cellular dysfunction. Nature communications, vol.8, 26-.

  43. Zhang, Ye, Kuang, Yi, Gao, Yuan, Xu, Bing. Versatile Small-Molecule Motifs for Self-Assembly in Water and the Formation of Biofunctional Supramolecular Hydrogels. Langmuir : the ACS journal of surfaces and colloids, vol.27, no.2, 529-537.

  44. Zheng, Zhen, Chen, Peiyao, Xie, Maolin, Wu, Chengfan, Luo, Yufeng, Wang, Wentao, Jiang, Jun, Liang, Gaolin. Cell Environment-Differentiated Self-Assembly of Nanofibers. Journal of the American Chemical Society, vol.138, no.35, 11128-11131.

  45. Yu, Haibo, Xiao, Yi, Jin, Liji. A Lysosome-Targetable and Two-Photon Fluorescent Probe for Monitoring Endogenous and Exogenous Nitric Oxide in Living Cells. Journal of the American Chemical Society, vol.134, no.42, 17486-17489.

  46. Li, Jie, Du, Xuewen, Hashim, Saqib, Shy, Adrianna, Xu, Bing. Aromatic–Aromatic Interactions Enable α-Helix to β-Sheet Transition of Peptides to Form Supramolecular Hydrogels. Journal of the American Chemical Society, vol.139, no.1, 71-74.

  47. Li, Jie, Zhan, Ziqing, Du, Xuewen, Wang, Jiaqing, Hong, Brandon, Xu, Bing. Selection of Secondary Structures of Heterotypic Supramolecular Peptide Assemblies by an Enzymatic Reaction. Angewandte Chemie. international edition, vol.57, no.36, 11716-11721.

  48. Kuang, Yi, Shi, Junfeng, Li, Jie, Yuan, Dan, Alberti, Kyle A., Xu, Qiaobing, Xu, Bing. Pericellular Hydrogel/Nanonets Inhibit Cancer Cells. Angewandte Chemie. international edition, vol.53, no.31, 8104-8107.

  49. Hidvegi, Tunda, Ewing, Michael, Hale, Pamela, Dippold, Christine, Beckett, Caroline, Kemp, Carolyn, Maurice, Nicholas, Mukherjee, Amitava, Goldbach, Christina, Watkins, Simon, Michalopoulos, George, Perlmutter, David H.. An Autophagy-Enhancing Drug Promotes Degradation of Mutant α 1 -Antitrypsin Z and Reduces Hepatic Fibrosis. Science, vol.329, no.5988, 229-232.

  50. Mutvei, Anders P., Nagiec, Michal J., Hamann, Jens C., Kim, Sang Gyun, Vincent, C. Theresa, Blenis, John. Rap1-GTPases control mTORC1 activity by coordinating lysosome organization with amino acid availability. Nature communications, vol.11, no.1, 1416-.

섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로