최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기Cells, v.11 no.8, 2022년, pp.1331 -
Kim, Juhee (Department of Food & Nutrition, Sungshin Women’s University, Seoul 01133, Korea) , Lee, Myoungsook (juheeq.kim@samsung.com)
Obesity causes various complications such as type 2 diabetes, hypertension, fatty liver, cardiovascular diseases, and cancer. In a pilot GWAS study, we screened the DNAJC6 gene which is significantly related to the resting metabolic rate (RMR) in childhood obesity. With DNAJC6-overexpressed 3T3-L1 c...
1. Qi L. Cho Y.A. Gene-environment interaction and obesity Nutr. Rev. 2008 66 684 694 10.1111/j.1753-4887.2008.00128.x 19019037
2. David A. Clevio N. Licinio M. Cristina P. The contribution of genetics and environment to obesity Br. Med. Bull. 2017 123 159 173 28910990
3. Day F.R. Loos R.J.F. Developments in obesity genetics in the era of Genome-wide association studies J. Nutrigenet. Nutrigenom. 2011 4 222 238 10.1159/000332158 22056736
4. Munoz Yanez C. Garcia Vargas G.G. Perez Morales R. Monogenic, polygenic and multifactorial obesity in children: Genetic and Environmental factors Austin J. Nutr. Metab. 2017 4 1052 1064
5. Lee M. Lee Y. Kang I. Shin J. Sorn S.R. RMR-Related MAP2K6 Gene Variation on the Risk of Overweight/Obesity in Children: A 3-Year Panel Study J. Pers. Med. 2021 11 91 10.3390/jpm11020091 33540643
6. Kang S.J. Lee M. Beiging Modulates Inflammatory Adipogenesis in Salt-Treated and MEK6 –Transfected Adipocytes Cells 2021 10 1106 10.3390/cells10051106 34064531
7. Lee S. Lee M. MEK6 Overexpression Exacerbates Fat Accumulation and Inflammatory Cytokines in High-Fat Diet-Induced Obesity Int. J. Mol. Sci. 2021 22 13559 10.3390/ijms222413559 34948353
8. Hasegawa T. Yoshida S. Sugeno N. Kobayshi J. Aoki M. DnaJ/Hsp40 family and Parkinson’s disease Front. Neurosci. 2018 11 743 10.3389/fnins.2017.00743 29367843
9. Ohtsuka K. Hata M. Mammalian HSP40/DNAJ homologs: Cloning of novel cDNAs and a proposal for their classification and nomenclature Cell Stress Chaperones 2000 5 98 112 10.1379/1466-1268(2000)005<0098:MHDHCO>2.0.CO;2 11147971
10. Olgiati S. Quadri M. Fang M. Rood J.P.M.A. Saute J.A. Chien H.F. Bouwkamp C.G. Graafland J. Minneboo M. Breedvled G.J. DNAJC6 Mutations Associated with Early-Onset Parkinson’s Disease Ann. Neurol. 2016 79 244 256 10.1002/ana.24553 26528954
12. Köroğlu C. Baysal L. Cetinkaya M. Karasoy H. Tolun A. DNAJC6 is responsible for juvenile parkinsonism with phenotypic variability Park. Relat. Disord. 2013 19 320 324 10.1016/j.parkreldis.2012.11.006
13. Vauthier V. Jaillard S. Journel H. Dubourg C. Jockers R. Dam J. Homozygous deletion of an 80kb region comprising part of DNAJC6 and LEPR genes on chromosome 1P31.3 is associated with early onset obesity, mental retardation and epilepsy Mol. Genet. Metab. 2012 106 345 350 10.1016/j.ymgme.2012.04.026 22647716
14. Yim Y.-I. Sun T. Wu L.-G. Raimondi A. De Camilli P. Eisenberg E. Greene L.E. Endocytosis and clathrin-uncoating defects at synapses of auxilin knockout mice Proc. Natl. Acad. Sci. USA 2010 107 4412 4417 10.1073/pnas.1000738107 20160091
15. Li Z. Srivastava P. Heat shock proteins Curr. Protoc. Immunol. 2004 58 1 6 10.1002/0471142735.ima01ts58
16. Yang T. Li X.-N. Li X.-G. Li M. Gao P.-Z. DNAJC6 promotes hepatocellular carcinoma progression through induction of epithelial–mesenchymal transition Biochem. Biophys. Res. Commun. 2014 455 298 304 10.1016/j.bbrc.2014.11.011 25446072
17. Zhao X. Greener T. Al-Hasani H. Cushman S. Eisenberg E. Greene L. Expression of auxilin or AP180 inhibits endocytosis by mislocalizing clathrin: Evidence for formation of nascent pits containing AP1 or AP2 but not clathrin J. Cell Sci. 2001 114 353 365 10.1242/jcs.114.2.353 11148137
18. Reichert M. Eick D. Analysis of cell cycle arrest in adipocyte differentiation Oncogene 1999 18 459 466 10.1038/sj.onc.1202308 9927202
19. Moseti D. Regassa A. Kim W.-K. Molecular Regulation of Adipogenesis and Potential Anti-Adipogenic Bioactive Molecules Int. J. Mol. Sci. 2016 17 124 10.3390/ijms17010124
20. Kwon H.J. Pessin J.E. Adipokines Mediate Inflammation and Insulin Resistance Front. Endocrinol. 2013 4 71 10.3389/fendo.2013.00071
21. Inoue G. Cheatham B. Emkey R. Kahn C.R. Dynamics of Insulin Signaling in 3T3-L1 Adipocytes J. Biol. Chem. 1998 273 11548 11555 10.1074/jbc.273.19.11548 9565570
22. Li J. DeFea K. Roth R.A. Modulation of Insulin Receptor Substrate-1 Tyrosine Phosphorylation by an Akt/Phosphatidylinositol 3-Kinase Pathway J. Biol. Chem. 1999 274 9351 9356 10.1074/jbc.274.14.9351 10092613
23. Rui L. Aguirre V. Kim J.K. Shulman G.I. Lee A. Corbould A. Dunaif A. White M.F. Insulin/IGF-1 and TNF-α stimulate phosphorylation of IRS-1 at inhibitory Ser307 via distinct pathways J. Clin. Investig. 2001 107 181 189 10.1172/JCI10934 11160134
24. Ronnett G.V. Knutson V.P. Lane M.D. Insulin-induced Down-Regulation of Insulin Receptors in 3T3-L1 Adipocytes. Altered Rate of Receptor Inactivation J. Biol. Chem. 1982 257 4285 4291 10.1016/S0021-9258(18)34719-7 7040381
25. Glasow A. Kiess W. Anderegg U. Berthold A. Bottner A. Kratzsch J. Expression of Leptin (Ob) and Leptin Receptor (Ob-R) in Human Fibroblasts: Regulation of Leptin Secretion by Insulin J. Clin. Endocrinol. Metab. 2001 86 4472 4479 10.1210/jcem.86.9.7792 11549696
26. Myers M.G. Jr. Leibel R.L. Seeley R.J. Schwartz M.W. Obesity and leptin resistance: Distinguishing cause from effect Trends Endocrinol. Metab. 2010 21 643 651 10.1016/j.tem.2010.08.002 20846876
27. Frühbeck G. A heliocentric view of leptin Proc. Nutr. Soc. 2001 60 301 318 10.1079/PNS200196 11681805
28. Ceddia R.B. Koistinen H.A. Zierath J. Sweeney G. Analysis of paradoxical observations on the association between leptin and insulin resistance FASEB J. 2002 16 1163 1176 10.1096/fj.02-0158rev 12153984
29. Martin S. Okano S. Kistler C. Fernandez-Rojo M.A. Hill M.M. Parton R. Spatiotemporal Regulation of Early Lipolytic Signaling in Adipocytes J. Biol. Chem. 2009 284 32097 32107 10.1074/jbc.M109.002675 19755426
30. Greenberg A.S. Shen W.-J. Muliro K. Patel S. Souza S.C. Roth R.A. Kraemer F.B. Stimulation of Lipolysis and Hormone-sensitive Lipase via the Extracellular Signal-regulated Kinase Pathway J. Biol. Chem. 2001 276 45456 45461 10.1074/jbc.M104436200 11581251
31. Shen W.-J. Yu Z. Patel S. Jue D. Liu L.-F. Kraemer F.B. Hormone-sensitive lipase modulates adipose metabolism through PPARγ Biochim. Biophys. Acta Mol. Cell Biol. Lipids 2011 1811 9 116 10.1016/j.bbalip.2010.10.001 20950707
32. Cho E. Jung W. Joo H.-Y. Park E.-R. Kim M.-Y. Kim S.-B. Kim K.S. Bin Lim Y. Lee K.H. Shin H.J. Cluh plays a pivotal role during adipogenesis by regulating the activity of mitochondria Sci. Rep. 2019 9 6820 10.1038/s41598-019-43410-4 31048716
33. Rousset S. Alves-Guerra M.-C. Mozo J. Miroux B. Cassard-Doulcier A.-M. Bouillaud F. Ricquier D. The Biology of Mitochondrial Uncoupling Proteins Diabetes 2004 53 S130 S135 10.2337/diabetes.53.2007.S130 14749278
34. Jastroch M. Divakaruni A.S. Mookerjee S. Treberg J.R. Brand M.D. Mitochondrial proton and electron leaks Essays Biochem. 2010 47 53 67 20533900
36. Mizushima N. Yoshimori T. How to Interpret LC3 Immunoblotting Autophagy 2007 3 542 545 10.4161/auto.4600 17611390
37. Thorburn A. Apoptosis and autophagy: Regulatory connections between two supposedly different processes Apoptosis 2007 13 1 9 10.1007/s10495-007-0154-9
*원문 PDF 파일 및 링크정보가 존재하지 않을 경우 KISTI DDS 시스템에서 제공하는 원문복사서비스를 사용할 수 있습니다.
오픈액세스 학술지에 출판된 논문
※ AI-Helper는 부적절한 답변을 할 수 있습니다.