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Telomerase and differentiation in multicellular organisms: Turn it off, turn it on, and turn it off again

Differentiation, v.69 no.4/5, 2002년, pp.188 - 197  

Forsyth, Nicholas R. (Department of Cell Biology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9039, USA) ,  Wright, Woodring E. (Fax: &plus) ,  Shay, Jerry W. (1 214 648 8694, Tel: &plus)

Abstract AI-Helper 아이콘AI-Helper

Abstract Telomerase is a ribonucleoprotein complex that catalyses the addition of TTAGGG repeats onto telomeres, repetitive DNA structures found at the ends of linear chromosomes. The majority of human somatic tissues do not display telomerase activity and undergo telomeric shortening with con...

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