[논문]Analysis of Select Dietary Supplement Products Marketed to Support or Boost the Immune System

Crawford, Cindy; Avula, Bharathi; Lindsey, Andrea T.; Walter, Abraham; Katragunta, Kumar; Khan, Ikhlas A.; Deuster, Patricia A.

doi:10.1001/jamanetworkopen.2022.26040

Analysis of Select Dietary Supplement Products Marketed to Support or Boost the Immune System 원문보기

Jama network open, v.5 no.8, 2022년, pp.e2226040 -

Crawford, Cindy (Consortium for Health and Military Performance, Department of Military and Emergency Medicine, F. Edward Hebert School of Medicine, Uniformed Services University, Bethesda, Maryland) , Avula, Bharathi (National Center for Natural Products Research, School of Pharmacy, University of Mississippi, University) , Lindsey, Andrea T. (Consortium for Health and Military Performance, Department of Military and Emergency Medicine, F. Edward Hebert School of Medicine, Uniformed Services University, Bethesda, Maryland) , Walter, Abraham (Consortium for Health and Military Performance, Department of Military and Emergency Medicine, F. Edward Hebert School of Medicine, Uniformed Services University, Bethesda, Maryland) , Katragunta, Kumar (National Center for Natural Products Research, School of Pharmacy, University of Mississippi, University) , Khan, Ikhlas A. (National Center for Natural Products Research, School of Pharmacy, University of Mississippi, University) , Deuster, Patricia A. (Consortium for Health and Military Performance, Department of Military and Emergency Medicine, F. Edward Hebert School of Medic)

Abstract ▼ AI-Helper

Key PointsQuestionAre select dietary supplement products advertised and sold to support or boost the immune system accurately labeled according to the Supplement Facts listed ingredients on product labels?FindingsThis case series study analyzed 30 dietary supplement products purchased from Amazon.com with claims related to immune health. Seventeen of 30 products had inaccurate labels; 13 were misbranded, and 9 had additional components detected but not claimed on the label.MeaningQuality control measures seem insufficient for most select dietary supplement products. The public has a right to know that they are buying what is stated on the label.This case series study examines the labeling of select dietary supplement products advertised as supporting or boosting the immune system for accurate ingredient labeling and claims made.ImportanceCold, flu, and immunity dietary supplement product sales have skyrocketed since the start of the COVID-19 pandemic. Supporting or boosting the immune system has become an important reason for using dietary supplements, and many consumers are purchasing products through online platforms.ObjectivesTo examine whether select dietary supplement products advertised as supporting or boosting the immune system are accurately labeled according to the Supplement Facts label of listed ingredients and to qualitatively describe the product labels’ characteristics in terms of claims made.Design, Setting, and ParticipantsIn this case series, 30 featured immune health dietary supplements were selected and purchased from Amazon.com in May 2021. Product analysis was performed using liquid chromatography–mass spectrometry. The list of ingredients detected through analysis for each product was compared with the ingredients on the product’s Supplement Facts label to determine whether the product’s label was accurate. Claims made on product labels were also evaluated by using the Operation Supplement Safety Scorecard’s set of questions to describe the labels’ characteristics.ResultsA total of 30 select dietary supplement products were evaluated. Thirteen of the 30 products had accurate labels based on the product analysis. Of the 17 products with inaccurate labels, 13 had ingredients listed on the labels that were not detected through analysis, such that their labels were misbranded. Nine products had substances detected that were not claimed on the product labels, some of which may be considered adulterated. Five were misbranded and contained additional components not claimed on the label. No product had third-party certification seals present on the packaging. Ten of the 13 products with accurate labels received a score of 4 or more when applying the Operation Supplement Safety Scorecard, meaning the product was “likely okay/less risky.”Conclusions and RelevanceIn this case series study, most of the products tested had inaccurate labels and claims that were inconsistent with requirements the US Food and Drug Administration has put forward for dietary supplements. Quality control measures seem to be insufficient for most of these select products, and claims made on labels may be misleading consumers who purchase products.

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Analysis of Select Dietary Supplement Products Marketed to Support or Boost the Immune System 원문보기

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