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Proceedings of the National Academy of Sciences of the United States of America, v.100 no.26, 2003년, pp.15352 - 15357
Pearson, Ann (Departments of Earth and Planetary Sciences and Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138) , Budin, Meytal (Departments of Earth and Planetary Sciences and Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138) , Brocks, Jochen J. (Departments of Earth and Planetary Sciences and Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138)
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Sterol biosynthesis is viewed primarily as a eukaryotic process, and the frequency of its occurrence in bacteria has long been a subject of controversy. Two enzymes, squalene monooxygenase and oxidosqualene cyclase, are the minimum necessary for initial biosynthesis of sterols from squalene. In thi...
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