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NTIS 바로가기Proceedings of the National Academy of Sciences of the United States of America, v.101 no.1, 2004년, pp.257 - 259
Pasqualini, Renata (University of Texas M. D. Anderson Cancer Center, Houston, TX 77030) , Arap, Wadih (University of Texas M. D. Anderson Cancer Center, Houston, TX 77030)
Production of monoclonal antibodies requires immortalization of splenocytes by somatic fusion to a myeloma cell line partner (hybridomas). Although hybridomas can be immortal, they may depend on a feeder cell layer and may be genetically unstable. Since the inception of hybridoma technology, efforts...
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