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Large-scale and effective screening of Korean medicinal plants for inhibitory activity on matrix metalloproteinase-9

Journal of ethnopharmacology, v.97 no.1, 2005년, pp.101 - 106  

Seo, Un-Kyo (Department of Internal Medicine, Biochemistry and Pathology, College of Oriental Medicine, Dongguk University, Kyungju City, Kyungbuk 780-714, Republic of Korea) ,  Lee, Young-Ja (Department of Internal Medicine, Biochemistry and Pathology, College of Oriental Medicine, Dongguk University, Kyungju City, Kyungbuk 780-714, Republic of Korea) ,  Kim, June-Ki (Department of Internal Medicine, Biochemistry and Pathology, College of Oriental Medicine, Dongguk University, Kyungju City, Kyungbuk 780-714, Republic of Korea) ,  Cha, Byung-Yoon (Department of Internal Medicine, Biochemistry and Pathology, College of Oriental Medicine, Dongguk University, Kyungju City, Kyungbuk 780-714, Republic of Korea) ,  Kim, Dong-Wook (Department of Internal Medicine, Biochemistry and Pathology, College of Oriental Medicine, Dongguk University, Kyungju City, Kyungbuk 780-714, Republic of Korea) ,  Nam, Kyung-Soo (Department of Pharmacology, College of Medicine, Dongguk University, Kyungju, Kyungbuk 780-714, Republic of Korea) ,  Kim, Cheorl-Ho (Department of Internal Medicine, Biochemistry and Pathology, College)

Abstract AI-Helper 아이콘AI-Helper

AbstractMatrix metalloproteinase-9 (MMP-9) degrades type IV collagen constituting the major structural component of the basement membrane and extra cellular membrane. The enzymatic activity is found to be elevated in tumor tissues. With the aim of finding novel MMP-9 inhibitors from natural products...

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참고문헌 (14)

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  2. Journal of Biochemistry and Molecular Biology Choi 35 236 2002 10.5483/BMBRep.2002.35.2.236 Relationship between acrylamide concentration and enzymatic activity in an improved single fibrin zymogram gel system 

  3. Annals of New York Academy of Sciences De 878 40 1999 10.1111/j.1749-6632.1999.tb07673.x The next generation of MMP inhibitors design and synthesis 

  4. Biochimica et Biophysica Acta Demeule 1478 51 2000 10.1016/S0167-4838(00)00009-1 Matrix metalloproteinase inhibition by green tea catechins 

  5. Canadian Medical Association Journal Kaegi 158 1033 1998 Unconventional therapies for cancer: 2. Green tea. The task force on alternative therapies of the canadian breast cancer research initiative 

  6. Cell Kim 94 353 1998 10.1016/S0092-8674(00)81478-6 Requirement for specific proteases in cancer cell intravasation as revealed by a novel semiquantitative PCR-based assay 

  7. Journal of Biochemistry and Molecular Biology Kwon 34 28 2001 Inhibitory effect of paeoniflorin on fos-Jun-DNA complex formation and stimulation of apoptosis in HL-60 Cells 

  8. Planta Medica Nagase 67 705 2001 10.1055/s-2001-18345 Inhibitory effect of magnolol and honokiol from Magnolia obovata on human fibrosarcoma HT-1080. Invasiveness in vitro 

  9. Bulletin of Tokyo Dentak College Osawa 32 1 1991 The inhibitory effect of plant extracts on the collagenolytic activity and cytotoxicity of human gingival fibroblasts by porphyromnas gingivalis crude enzyme 

  10. American Journal of Physiology Partridge 272 812 1997 Localization and activation of type IV collagenase/gelatinase at endothelial focal contacts 

  11. Drugs R&D Sugita 2 327 1999 Recent advances in inhibitors of metalloproteinases for cancer therapy 

  12. Drugs R&D Wojtowicz-Praga 1 117 1999 10.2165/00126839-199901020-00001 Clinical potential of matrix metalloprotenase inhibitors 

  13. Cancer Research Yano 54 448 1994 The herbal medicine sho-saiko-to inhibits proliferation of cancer cell lines by inducing apoptosis and arrest at the G0/G1 phase 

  14. Chemical and Pharmaceutical Bulletin Yoshikawa 48 1327 2000 10.1248/cpb.48.1327 Bioactive constituents of Chinese natural medicines 

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