Napier, Mary E.
(Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC)
,
DeSimone, Joseph M.
(Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC,Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC,Department of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, NC)
The use of polymers and polymeric structures in the treatment, diagnosis, and monitoring of biological systems is continuing to increase in sophistication. Research exploring the use of nanoparticles for drug delivery applications has included the exploration and development of nanocolloids, liposo...
The use of polymers and polymeric structures in the treatment, diagnosis, and monitoring of biological systems is continuing to increase in sophistication. Research exploring the use of nanoparticles for drug delivery applications has included the exploration and development of nanocolloids, liposomes, micelles, nanogels, polymer-drug conjugates, and a variety of other polymeric nanoparticles that are composed of organic polymers with specific physical or chemical properties that make them relevant delivery vehicles. One of the current trends is the fabrication of tunable, mono-dispersed, polymeric nanostructures to be used as nanoparticle drug delivery platforms. The PRINT technology used to fabricate monodisperse particles from a wide range of particle matrix materials including biocompatible poly(ethylene glycol) and bioabsorbable poly(d-lactic acid) is described along with an abbreviated overview of other polymeric drug delivery platforms.
The use of polymers and polymeric structures in the treatment, diagnosis, and monitoring of biological systems is continuing to increase in sophistication. Research exploring the use of nanoparticles for drug delivery applications has included the exploration and development of nanocolloids, liposomes, micelles, nanogels, polymer-drug conjugates, and a variety of other polymeric nanoparticles that are composed of organic polymers with specific physical or chemical properties that make them relevant delivery vehicles. One of the current trends is the fabrication of tunable, mono-dispersed, polymeric nanostructures to be used as nanoparticle drug delivery platforms. The PRINT technology used to fabricate monodisperse particles from a wide range of particle matrix materials including biocompatible poly(ethylene glycol) and bioabsorbable poly(d-lactic acid) is described along with an abbreviated overview of other polymeric drug delivery platforms.
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