$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

[해외논문] Senescence‐associated β‐galactosidase is lysosomal β‐galactosidase 원문보기

Aging cell, v.5 no.2, 2006년, pp.187 - 195  

Lee, Bo Yun ,  Han, Jung A. ,  Im, Jun Sub ,  Morrone, Amelia ,  Johung, Kimberly ,  Goodwin, Edward C. ,  Kleijer, Wim J. ,  DiMaio, Daniel ,  Hwang, Eun Seong

Abstract AI-Helper 아이콘AI-Helper

SummaryReplicative senescence limits the proliferation of somatic cells passaged in culture and may reflect cellular aging in vivo. The most widely used biomarker for senescent and aging cells is senescence‐associated β‐galactosidase (SA‐β‐gal), which is defined...

참고문헌 (48)

  1. BOSMANN, H. BRUCE, GUTHEIL JR, ROGER L., CASE, KENNETH R.. Loss of a critical neutral protease in ageing WI-38 cells. Nature, vol.261, no.5560, 499-501.

  2. Braig, Melanie, Lee, Soyoung, Loddenkemper, Christoph, Rudolph, Cornelia, Peters, Antoine H.F.M., Schlegelberger, Brigitte, Stein, Harald, Dörken, Bernd, Jenuwein, Thomas, Schmitt, Clemens A.. Oncogene-induced senescence as an initial barrier in lymphoma development. Nature, vol.436, no.7051, 660-665.

  3. Bringold, Frank, Serrano, Manuel. Tumor suppressors and oncogenes in cellular senescence☆. Experimental gerontology, vol.35, no.3, 317-329.

  4. Brunk, U., Ericsson, J.L.E., Pontén, J., Westermark, B.. Residual bodies and “aging” in cultured human glia cells. Experimental cell research, vol.79, no.1, 1-14.

  5. Caciotti, Anna, Donati, Maria Alice, Boneh, Avihu, d'Azzo, Alessandra, Federico, Antonio, Parini, Rossella, Antuzzi, Danielas, Bardelli, Tiziana, Nosi, Daniele, Kimonis, Virginia, Zammarchi, Enrico, Morrone, Amelia. Role of &bgr;-galactosidase and elastin binding protein in lysosomal and nonlysosomal complexes of patients with GM1-gangliosidosis. Human mutation, vol.25, no.3, 285-292.

  6. Campisi, Judith. Senescent Cells, Tumor Suppression, and Organismal Aging: Good Citizens, Bad Neighbors. Cell, vol.120, no.4, 513-522.

  7. Chen, Q, Fischer, A, Reagan, J D, Yan, L J, Ames, B N. Oxidative DNA damage and senescence of human diploid fibroblast cells.. Proceedings of the National Academy of Sciences of the United States of America, vol.92, no.10, 4337-4341.

  8. Coates, Philip J.. Markers of senescence?. The Journal of pathology : a journal of the Pathological Society of Great Britain and Ireland, vol.196, no.4, 371-373.

  9. Collado, Manuel, Gil, Jesús, Efeyan, Alejo, Guerra, Carmen, Schuhmacher, Alberto J., Barradas, Marta, Benguría, Alberto, Zaballos, Angel, Flores, Juana M., Barbacid, Mariano, Beach, David, Serrano, Manuel. Tumour biology: Senescence in premalignant tumours. Nature, vol.436, no.7051, 642-642.

  10. Cristofalo, V.J.. SA β Gal staining: Biomarker or delusion. Experimental gerontology, vol.40, no.10, 836-838.

  11. Cristofalo, V.J., Kabakjian, J.. Lysosomal enzymes and aging in vitro: Subcellular enzyme distribution and effect of hydrocortisone on cell life-span. Mechanisms of ageing and development, vol.4, 19-28.

  12. Dacremont, G., Kint, J.A.. Gml-ganglioside accumulation and β-galactosidase deficiency in a case of Gml-gangliosidosis (Landing disease). Clinica chimica acta, vol.21, no.3, 421-425.

  13. DeFilippis, Rosa Anna, Goodwin, Edward C., Wu, Lingling, DiMaio, Daniel. Endogenous Human Papillomavirus E6 and E7 Proteins Differentially Regulate Proliferation, Senescence, and Apoptosis in HeLa Cervical Carcinoma Cells. Journal of virology, vol.77, no.2, 1551-1563.

  14. Dimri, G P, Lee, X, Basile, G, Acosta, M, Scott, G, Roskelley, C, Medrano, E E, Linskens, M, Rubelj, I, Pereira-Smith, O. A biomarker that identifies senescent human cells in culture and in aging skin in vivo.. Proceedings of the National Academy of Sciences of the United States of America, vol.92, no.20, 9363-9367.

  15. Dimri, Goberdhan P., Testori, A., Acosta, Meileen, Campisi, Judith. Replicative Senescence, Aging and Growth-Regulatory Transcription Factors. Biological signals, vol.5, no.3, 154-162.

  16. Ferland, G., Perea, A., Audet, M., Tuchweber, B.. Characterization of liver lysosomal enzyme activity in hepatocytes, Kupffer and endothelial cells during aging: Effect of dietary restriction. Mechanisms of ageing and development, vol.56, no.2, 143-154.

  17. Gary, Ronald K., Kindell, Susan M.. Quantitative assay of senescence-associated β-galactosidase activity in mammalian cell extracts. Analytical biochemistry, vol.343, no.2, 329-334.

  18. Gerland, Luc-Marie, Peyrol, Simone, Lallemand, Christophe, Branche, Robert, Magaud, Jean-Pierre, Ffrench, Martine. Association of increased autophagic inclusions labeled for β-galactosidase with fibroblastic aging. Experimental gerontology, vol.38, no.8, 887-895.

  19. Goodwin, Edward C., Yang, Eva, Lee, Chan-Jae, Lee, Han-Woong, DiMaio, Daniel, Hwang, Eun-Seong. Rapid induction of senescence in human cervical carcinoma cells. Proceedings of the National Academy of Sciences of the United States of America, vol.97, no.20, 10978-10983.

  20. Hayflick, L., Moorhead, P.S.. The serial cultivation of human diploid cell strains. Experimental cell research, vol.25, no.3, 585-621.

  21. Hwang, Eun Seong. Replicative senescence and senescence-like state induced in cancer-derived cells. Mechanisms of ageing and development, vol.123, no.12, 1681-1694.

  22. J. Virol. Hwang ES 3720 67 1993 10.1128/jvi.67.7.3720-3729.1993 Inhibition of cervical carcinoma cell line proliferation by introduction of a bovine papillomavirus regulatory gene 

  23. Kang, Hyun Tae, Lee, Chan Jae, Seo, Eun Jeong, Bahn, Young Jae, Kim, Hyun Jung, Hwang, Eun Seong. Transition to an irreversible state of senescence in HeLa cells arrested by repression of HPV E6 and E7 genes. Mechanisms of ageing and development, vol.125, no.1, 31-40.

  24. 10.1007/978-1-4757-0731-1_12 

  25. Krishna, Devarakonda R, Sperker, Bernhard, Fritz, Peter, Klotz, Ulrich. Does pH 6 β-galactosidase activity indicate cell senescence?. Mechanisms of ageing and development, vol.109, no.2, 113-123.

  26. Kurz, David J., Decary, Stephanie, Hong, Ying, Erusalimsky, Jorge D.. Senescence-associated β-galactosidase reflects an increase in lysosomal mass during replicative ageing of human endothelial cells. Journal of cell science, vol.113, no.20, 3613-3622.

  27. Melk, Anette, Kittikowit, Wipawee, Sandhu, Irwindeep, Halloran, Kieran M, Grimm, Paul, Schmidt, Bernhard M W, Halloran, Philip F. Cell senescence in rat kidneys in vivo increases with growth and age despite lack of telomere shortening. Kidney international, vol.63, no.6, 2134-2143.

  28. Michaloglou, Chrysiis, Vredeveld, Liesbeth C. W., Soengas, Maria S., Denoyelle, Christophe, Kuilman, Thomas, van der Horst, Chantal M. A. M., Majoor, Donné M., Shay, Jerry W., Mooi, Wolter J., Peeper, Daniel S.. BRAFE600-associated senescence-like cell cycle arrest of human naevi. Nature, vol.436, no.7051, 720-724.

  29. Invest. Ophthalmol. Vis. Sci. Mishima K 1590 40 1999 Senescence‐associated β‐galactosidase histochemistry for the primate eye 

  30. Norden, A G, O'Brien, J S. An electrophoretic variant of beta-galactosidase with altered catalytic properties in a patient with GM1 gangliosidosis.. Proceedings of the National Academy of Sciences of the United States of America, vol.72, no.1, 240-244.

  31. Oshima, Akihiro, Yoshida, Kunihiro, Itoh, Kohji, Kase, Ryoichi, Sakuraba, Hitoshi, Suzuki, Yoshiyuki. Intracellular processing and maturation of mutant gene products in hereditary ?-galactosidase deficiency (?-galactosidosis). Human genetics, vol.93, no.2,

  32. 10.1002/(SICI)1097-4652(199907)180:1<123::AID-JCP14>3.0.CO;2-W 

  33. Robbins, E., Levine, E. M., Eagle, H.. MORPHOLOGIC CHANGES ACCOMPANYING SENESCENCE OF CULTURED HUMAN DIPLOID CELLS. The Journal of experimental medicine, vol.131, no.6, 1211-1222.

  34. Sánchez-Martı́n, M.-Mario, Cabezas, José A. Evaluation of the activities of eight lysosomal hydrolases in sera of humans, rats and pigs of different ages. Mechanisms of ageing and development, vol.99, no.2, 95-107.

  35. Serrano, Manuel, Lin, Athena W, McCurrach, Mila E, Beach, David, Lowe, Scott W. Oncogenic ras Provokes Premature Cell Senescence Associated with Accumulation of p53 and p16INK4a. Cell, vol.88, no.5, 593-602.

  36. Severino, J., Allen, R.G., Balin, S., Balin, A., Cristofalo, V.J.. Is β-Galactosidase Staining a Marker of Senescence in Vitro and in Vivo?. Experimental cell research, vol.257, no.1, 162-171.

  37. Shay, Jerry W, Roninson, Igor B. Hallmarks of senescence in carcinogenesis and cancer therapy. Oncogene, vol.23, no.16, 2919-2933.

  38. Sigal, Samuel H., Rajvanshi, Pankaj, Gorla, Giridhar R., Sokhi, Rana P., Saxena, Romil, Gebhard Jr., David R., Reid, Lola M., Gupta, Sanjeev. Partial hepatectomy-induced polyploidy attenuates hepatocyte replication and activates cell aging events. American journal of physiology, Gastrointestinal and liver physiology, vol.276, no.5, G1260-G1272.

  39. 10.1002/(SICI)1098-1004(1999)13:5<401::AID-HUMU9>3.0.CO;2-N 

  40. Song, Young Sook, Lee, Bo Yun, Hwang, Eun Seong. Dinstinct ROS and biochemical profiles in cells undergoing DNA damage-induced senescence and apoptosis. Mechanisms of ageing and development, vol.126, no.5, 580-590.

  41. Turk, Beatrice, Milo, George E.. An in vitro study of senescent events of human embryonic lung (WI-38) cells. Archives of biochemistry and biophysics, vol.161, no.1, 46-53.

  42. Untergasser, G., Gander, R., Rumpold, H., Heinrich, E., Plas, E., Berger, P.. TGF-β cytokines increase senescence-associated beta-galactosidase activity in human prostate basal cells by supporting differentiation processes, but not cellular senescence. Experimental gerontology, vol.38, no.10, 1179-1188.

  43. Wells, S I, Francis, D A, Karpova, A Y, Dowhanick, J J, Benson, J D, Howley, P M. Papillomavirus E2 induces senescence in HPV-positive cells via pRB- and p21(CIP)-dependent pathways.. The EMBO journal, vol.19, no.21, 5762-5771.

  44. Yang, Nae-Cherng, Hu, Miao-Lin. The limitations and validities of senescence associated-β-galactosidase activity as an aging marker for human foreskin fibroblast Hs68 cells. Experimental gerontology, vol.40, no.10, 813-819.

  45. Yegorov, Y.E., Akimov, S.S., Hass, R., Zelenin, A.V., Prudovsky, I.A.. Endogenous β-Galactosidase Activity in Continuously Nonproliferating Cells. Experimental cell research, vol.243, no.1, 207-211.

  46. Zhang, S, McCarter, J D, Okamura-Oho, Y, Yaghi, F, Hinek, A, Withers, S G, Callahan, J W. Kinetic mechanism and characterization of human β-galactosidase precursor secreted by permanently transfected Chinese hamster ovary cells. The Biochemical journal, vol.304, no.1, 281-288.

  47. Zhu, Jiyue, Woods, Douglas, McMahon, Martin, Bishop, J. Michael. Senescence of human fibroblasts induced by oncogenic Raf. Genes & development, vol.12, no.19, 2997-3007.

  48. von Zglinicki, T., Nilsson, E., Döcke, W.D., Brunk, U.T.. LIPOFUSCIN ACCUMULATION AND AGEING OF FIBROBLASTS. Gerontology, vol.41, no.suppl2, 95-108.

활용도 분석정보

상세보기
다운로드
내보내기

활용도 Top5 논문

해당 논문의 주제분야에서 활용도가 높은 상위 5개 콘텐츠를 보여줍니다.
더보기 버튼을 클릭하시면 더 많은 관련자료를 살펴볼 수 있습니다.

관련 콘텐츠

오픈액세스(OA) 유형

BRONZE

출판사/학술단체 등이 한시적으로 특별한 프로모션 또는 일정기간 경과 후 접근을 허용하여, 출판사/학술단체 등의 사이트에서 이용 가능한 논문

이 논문과 함께 이용한 콘텐츠

저작권 관리 안내
섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로