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Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice 원문보기

The Journal of clinical investigation, v.118 no.3, 2008년, pp.829 - 838  

Postic, Catherine ,  Girard, Jean

Abstract AI-Helper 아이콘AI-Helper

Nonalcoholic fatty liver disease (NAFLD) is associated with obesity, insulin resistance, and type 2 diabetes. NAFLD represents a large spectrum of diseases ranging from (i) fatty liver (hepatic steatosis); (ii) steatosis with inflammation and necrosis; and (iii) cirrhosis. Although the molecular mec...

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