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[해외논문] Melatonin suppresses AOM/DSS-induced large bowel oncogenesis in rats

Chemico-biological interactions, v.177 no.2, 2009년, pp.128 - 136  

Tanaka, T. (Department of Oncologic Pathology, Kanazawa Medical University, 1-1 Daigaku, Uchinada, Ishikawa 920-0293, Japan) ,  Yasui, Y. (Department of Oncologic Pathology, Kanazawa Medical University, 1-1 Daigaku, Uchinada, Ishikawa 920-0293, Japan) ,  Tanaka, M. (Department of Oncologic Pathology, Kanazawa Medical University, 1-1 Daigaku, Uchinada, Ishikawa 920-0293, Japan) ,  Tanaka, T. ,  Oyama, T. ,  Rahman, K.W.

Abstract AI-Helper 아이콘AI-Helper

The inhibitory effects of exogenous melatonin (MEL) on colon oncogenesis were investigated using an azoxymethane (AOM)/dextran sodium sulfate (DSS) rat model. Male F344 rats initiated with a single intraperitoneal injection of AOM (20mg/kg bw) were promoted by 1% (w/v) DSS in drinking water for 7 da...

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