[논문]Effects of Music Therapy on Autonomic Nervous System Activity, Incidence of Heart Failure Events, and Plasma Cytokine and Catecholamine Levels in Elderly Patients With Cerebrovascular Disease and Dementia

Okada, Kaoru; Kurita, Akira; Takase, Bonpei; Otsuka, Toshiaki; Kodani, Eitaro; Kusama, Yoshiki; Atarashi, Hirotsugu; Mizuno, Kyoichi

Effects of Music Therapy on Autonomic Nervous System Activity, Incidence of Heart Failure Events, and Plasma Cytokine and Catecholamine Levels in Elderly Patients With Cerebrovascular Disease and Dementia

International heart journal, v.50 no.1, 2009년, pp.95 - 110

Okada, Kaoru (Department of Internal Medicine and Cardiology, Nippon Medical School Tama-Nagayama Hospital) , Kurita, Akira (Fukuinkai Medical Clinic) , Takase, Bonpei (Division of Biomedical Engineering, National Defense Medical College Research Institute) , Otsuka, Toshiaki (Department of Hygiene and Public Health, Nippon Medical School) , Kodani, Eitaro (Department of Internal Medicine and Cardiology, Nippon Medical School Tama-Nagayama Hospital) , Kusama, Yoshiki (Department of Internal Medicine and Cardiology, Nippon Medical School Tama-Nagayama Hospital) , Atarashi, Hirotsugu (Department of Internal Medicine and Cardiology, Nippon Medical School Tama-Nagayama Hospital) , Mizuno, Kyoichi (Department of Internal Medicine and Cardiology, Nippon Medical School)

Abstract ▼ AI-Helper

Music therapy (MT) has been used in geriatric nursing hospitals, but there has been no extensive research into whether it actually has beneficial effects on elderly patients with cerebrovascular disease (CVD) and dementia. We investigated the effects of MT on the autonomic nervous system and plasma cytokine and catecholamine levels in elderly patients with CVD and dementia, since these are related to aging and chronic geriatric disease. We also investigated the effects of MT on congestive heart failure (CHF) events.Eighty-seven patients with pre-existing CVD were enrolled in the study. We assigned patients into an MT group (n = 55) and non-MT group (n = 32). The MT group received MT at least once per week for 45 minutes over 10 times. Cardiac autonomic activity was assessed by heart rate variability (HRV). We measured plasma cytokine and catecholamine levels in both the MT group and non-MT group. We compared the incidence of CHF events between these two groups. In the MT group, rMSSD, pNN50, and HF were significantly increased by MT, whereas LF/HF was slightly decreased. In the non-MT group, there were no significant changes in any HRV parameters. Among cytokines, plasma interleukin-6 (IL-6) in the MT group was significantly lower than those in the non-MT group. Plasma adrenaline and noradrenaline levels were significantly lower in the MT group than in the non-MT group. CHF events were less frequent in the MT group than in the non-MT group (P < 0.05). These findings suggest that MT enhanced parasympathetic activities and decreased CHF by reducing plasma cytokine and catecholamine levels.

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참고문헌 (50)

1. Kokumin Eisei no Doukou . Vol. 52. In: Jinkou doutai. Tokyo: Health and Welfare Statistics Association; 2006: 33-7. (Japanese)
10.1212/WNL.45.6.1161 2. Yoshitake T, Kiyohara Y, Kato I, et al . Incidence and risk factors of vascular dementia and Alzheimer's disease in a defined elderly Japanese population: the Hisayama Study. Neurology 1995; 45: 1161-8.

상세보기
10.3143/geriatrics.43.152 3. Matsumoto M. Cerebrovascular disease in the elderly people. Nippon Ronen Igakkai Zasshi 2006; 43: 152-4. (Japanese)

상세보기
10.3928/0098-9134-19950901-07 4. Bradley L, Siddique CM, Dufton B. Reducing the use of physical restraints in long-term care facilities. J Gerontol Nurs 1995; 21: 21-34.

상세보기
5. Hall GR, Buckwalter KC. Progressively lowered stress threshold: a conceptual model for care of adults with Alzheimer's disease. Arch Psychiatr Nurs 1987; 1: 399-406.
6. Thomas DR. Assessment and management of agitation in the elderly. Geriatrics 1988; 43: 45-50, 53.
7. Meyer LB. Emotion and meaning in music . Chicago: University of Chicago, IL; 1956: 1-23.
8. Munro S, Mount B. Music therapy in palliative care. Can Med Assoc J 1978; 119: 1029-34.
9. Guzzetta CE. Music therapy: Healing the melody of the soul. In: Holistic Nursing. A Handbook for Practice . Dossey BM, Keegan L, Guzzetta CE (Eds). Gaitherburg, Aspen, MD; 1995: 679-98.
10.1016/j.gerinurse.2004.08.009 10. Lai HL. Music preference and relaxation in Taiwanese elderly people. Geriatr Nurs 2004; 25: 286-91.

상세보기
11. Vollert JO, Störk T, Rose M, Möckel, M. Music as adjuvant therapy for coronary heart disease. Therapeutic music lowers anxiety, stress and beta-endorphin concentrations in patients from a coronary sport group. Dtsch Med Wochenschr 2003; 128: 2712-6. (German)
10.4037/ccn1999.19.3.35 12. Chlan L, Tracy MF. Music therapy in critical care: Indications and guidelines for intervention. Crit Care Nurse 1990; 19: 35-41. (Review)

상세보기
10.1016/S0147-9563(05)80007-X 13. Barnason S, Zimmerman L, Nieveen J. The effects of music interventions on anxiety in the patient after coronary artery bypass grafting. Heart Lung 1995; 24: 124-32.

상세보기
10.1097/00002800-199200620-00002 14. White JM. Music therapy: an intervention to reduce anxiety in the myocardial infarction patient. Clin Nurse Spec 1992; 6: 58-63.

상세보기
10.1016/j.jacc.2004.04.030 15. Carney RM, Freedland KE, Jaffe AS, et al . Depression as a risk factor for post-MI mortality. J Am Coll Cardiol 2004; 44: 472.

상세보기
10.1016/j.jacc.2007.01.075 16. Dickens C, McGowan L, Percival C, et al . Depression is a risk factor for mortality after myocardial infarction: Fact or artifact? J Am Coll Cardiol 2007; 49: 1834-40.

상세보기
10.1093/gerona/61.6.575 17. Maggio M, Gruralnik JM, Longo DL, Ferrucci L. Interleukin-6 in aging and chronic disease: A magnificent pathway. J Gerontol A Biol Sci Med Sci 2006; 61: 575-84. (Review)

상세보기
10.1111/j.1532-5415.1993.tb02054.x 18. Ershler WB. Interleukin-6: a cytokine for gerontologists. J Am Geriatr Soc 1993; 41: 176-81. (Review)

상세보기
10.1016/0024-3205(92)90112-3 19. Wei J, Xu H, Davies JL, Hemmings GP. Increase of plasma IL-6 concentration with age in healthy subjects. Life Sci 1992; 51: 1953-56.

상세보기
10.1152/ajpregu.1998.274.3.R577 20. Meldrum DR. Tumor necrosis factor in the heart. Am J Physiol 1998; 274: R577-95. (Review)

상세보기
10.1111/j.1532-5415.1999.tb01583.x 21. Ferrucci L, Harris TB, Guralnik JM, et al . Serum IL-6 level and the development of disability in older persons. J Am Geriatr Soc 1999; 47: 639-46.

상세보기
10.1136/bmj.313.7070.1448a 22. Declaration of Helsinki (1964). BMJ 1996; 313: 1448-9.

상세보기
23. Kobayashi T, Hataguchi K, Nishimura K, et al . Simple dementia scale. Rinsho Seishingaku 1988; 17: 1653-68. (Japanese)
10.1161/CIRCULATIONAHA.105.167586 24. Hunt SA, Abraham WT, Chin MH, et al ; American College of Cardiology; American Heart Association Task Force on Practice Guidelines; American College of Chest Physicians; International Society forHeart and Lung Transplantation; Heart Rhythm Society. ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Update the 2001 Guidelines for the Evaluation and Management of Heart Failure): developed in collaboration with the American College of Chest Physicians and the International Society for Heart and Lung Transplantation: endorsed by the Heart Rhythm Society. Circulation 2005; 112: e154-235.

상세보기
10.1143/JPSJ.65.2811 25. Ohtomo N, Sumi A, Tanaka Y, Tokiwano K, Terachi S. A detailed study of power spectral density for Rossler system. J Phy Soc Jpn 1996; 65: 2811-23.

상세보기
26. Heart Rate Variability: standards of measurement, physiological interpretation and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Circulation 1996; 93: 1043-65.
10.1016/0022-0736(88)90055-6 27. Singer DH, Martin GJ, Magid N, et al . Low heart rate variability and sudden cardiac death. J Electrocardiol 1988; 21: S46-55. (Review)

상세보기
10.1016/S0033-0620(96)80011-9 28. Anderson KP, Bigger JT Jr, Freedman RA. Electrocardiographic predictors in the ESVEM trial: unsustained ventricular tachycardia, heart period variability, and the signal-averaged electrocardiogram. Prog Cardiovasc Dis 1996; 38: 463-88. (Review)

상세보기
10.1097/00001573-199801000-00006 29. Malik M. Heart rate variability. Curr Opin Cardiol 1998; 13: 36-44. (Review)

상세보기
30. Kurita A, Hamabe A, Takase B, Hikita H, Nagayoshi H. Usefulness of a single time-domain heart rate variability index for assessment of cardiac events. Analysis of circadian cardiac autonomic tone, cardiac risk factors, and QT intervals. J Natl Def Med Coll 1999; 24: 125-36.
10.1161/CIRCULATIONAHA.104.518449 31. Guzzetti S, Borroni E, Garbelli PE, et al . Symbolic dynamics of heart rate variability: a probe to investigate cardiac autonomic modulation. Circulation 2005; 112: 465-70.

상세보기
32. Kurita A, Matsui T, Ishizuka T, Takase B, Satomura K. Modulation of electrical microvolt level T-wave alternans and left ventricular late potentials evaluated by heart rate variability indices, QT dispersion, and plasma catecholamine levels. A.N.E. 2000; 5: 262-9.
10.1016/S1880-4276(06)80014-1 33. Kurita A, Takase B, Okada K, et al . Effects of music therapy on heart rate variability in elderly patients with cerebral vascular disease and dementia. J Arrhythmia 2006; 22: 161-6.

상세보기
10.1161/CIRCULATIONAHA.104.532259 34. Ikonomidis I, Athanassopoulos G, Lekakis J, et al . Myocardial ischemia induces interleukin-6 and tissue factor production in patients with coronary artery disease: a dobutamine stress echocardiography study. Circulation 2005; 112: 3272-9.

상세보기
10.1161/01.CIR.0000060808.79274.0C 35. Murray DR, Freeman GL. Proinflammatory cytokines: predictors of a failing heart? Circulation 2003; 107: 1460-2.

상세보기
10.1038/nature01321 36. Tracey KJ. The inflammatory reflex. Nature 2002; 420: 853-9. (Review)

상세보기
10.1161/01.CIR.0000057810.48709.F6 37. Vasan RS, Sullivan LM, Roubenoff R, et al ; Framingham Heart Study. Inflammatory markers and risk of heart failure in elderly subjects without prior myocardial infarction: The Framingham Heart Study. Circulation 2003; 107: 1486-91.

상세보기
10.4049/jimmunol.132.3.1067 38. Blalock JE. The immune system as a sensory organ. J Immunol 1984; 132: 1067-70. (Review)

상세보기
10.1111/j.1749-6632.1994.tb23112.x 39. Blalock JE. Shared ligands and receptors as a molecular mechanism for communication between the immune and neuroendocrine systems. Ann N Y Acad Sci 1994; 741: 292-8. (Review)

상세보기
10.1093/eurheartj/4.suppl_A.49 40. Malliani A, Pagani M. The role of the sympathetic nervous system in congestive heart failure. Eur Heart J 1983; 4: 49-54.

상세보기
10.1054/mehy.1999.0029 41. Davila DF, Donis JH, Ballabarbe, G, Torres A, Casado J, Mazzei de Davila C. Cardiac afferents and neurohormonal activation in congestive heart failure. Med Hypotheses 2000; 54: 242-53.

상세보기
10.1007/BF02005179 42. Zucker IH. Left ventricular receptors: physiological controllers or pathological curiosities? Basic Res Cardiol 1986; 81: 539-57. (Review)

상세보기
10.1111/j.1445-5994.1990.tb01325.x 43. Ludbrook J. Cardiovascular reflexes from cardiac sensory receptors. Aust N Z J Med 1990; 20: 597-606. (Review)

상세보기
10.1152/physrev.1991.71.3.617 44. Hainsworth R. Reflexes from the heart. Physiol Rev 1991; 71: 617-58. (Review)

상세보기
10.1007/BFb0031531 45. Thorén P. Role of cardiac vagal C-fibers in cardiovascular control. Rev Physiol Biochem Pharmacol 1979; 86: 1-94. (Review)
10.1002/cphy.cp020324 46. Gilmore JP. Neural control of extracellular volume in the human and nonhuman primate. In: Handbook of Physiology. Vol III. The Cardiovascular System . Shepherd JT, Abboud AM (Eds) Waverly Press, Bethesda, MD; 1983: 885-9.
10.1152/physrev.1997.77.1.75 47. DiBona GF, Kopp UC. Neural control of renal function. Physiol Rev 1997; 77: 75-197. (Review)

상세보기
10.1172/JCI114580 48. Porter TR, Eckberg DL, Fritsch JM, et al . Autonomic pathophysiology in heart failure patients. Sympathetic-cholinergic interrelations. J Clin Invest 1990; 85: 1362-71.

상세보기
10.1054/mehy.1999.0029 49. Davila DF, Donis JH, Bellabarba G, Torres A, Casado J, Mazzei de Davila C. Cardiac afferents and neurohormonal activation in congestive heart failure. Med Hypotheses 2000; 54: 242-53.

상세보기
10.1016/j.cardiores.2005.02.012 50. Kaye D, Esler M. Sympathetic neuronal regulation of the heart in aging and heart failure. Cardiovasc Res 2005; 66: 256-64. (Review)

상세보기

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Effects of Music Therapy on Autonomic Nervous System Activity, Incidence of Heart Failure Events, and Plasma Cytokine and Catecholamine Levels in Elderly Patients With Cerebrovascular Disease and Dementia

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