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NTIS 바로가기IUBMB life, v.62 no.11, 2010년, pp.791 - 796
Sola‐Penna, Mauro , Da Silva, Daniel , Coelho, Wagner S. , Marinho‐Carvalho, Monica M. , Zancan, Patricia
AbstractPhosphofructokinase (PFK) is a major regulatory glycolytic enzyme and is considered to be the pacemaker of glycolysis. This enzyme presents a puzzling regulatory mechanism that is modulated by a large variety of metabolites, drugs, and intracellular proteins. To date, the mammalian enzyme st...
Li, Y., Rivera, D., Ru, W., Gunasekera, D., Kemp, R. G.. Identification of Allosteric Sites in Rabbit Phosphofructo-1-kinase. Biochemistry, vol.38, no.49, 16407-16412.
Vora, S, Francke, U. Assignment of the human gene for liver-type 6-phosphofructokinase isozyme (PFKL) to chromosome 21 by using somatic cell hybrids and monoclonal anti-L antibody.. Proceedings of the National Academy of Sciences of the United States of America, vol.78, no.6, 3738-3742.
Dunaway, G A, Kasten, T P, Sebo, T, Trapp, R. Analysis of the phosphofructokinase subunits and isoenzymes in human tissues. The Biochemical journal, vol.251, no.3, 677-683.
Zancan, P., Sola-Penna, M., Furtado, C.M., Da Silva, D.. Differential expression of phosphofructokinase-1 isoforms correlates with the glycolytic efficiency of breast cancer cells. Molecular genetics and metabolism, vol.100, no.4, 372-378.
Faber-Barata, Joana, Sola-Penna, Mauro. Opposing effects of two osmolytes ? trehalose and glycerol ? on thermal inactivation of rabbit muscle 6-phosphofructo-1-kinase. Molecular and cellular biochemistry, vol.269, no.1, 203-207.
Zancan, Patricia, Almeida, Fernanda V.R., Faber-Barata, Joana, Dellias, João Marcelo, Sola-Penna, Mauro. Fructose-2,6-bisphosphate counteracts guanidinium chloride-, thermal-, and ATP-induced dissociation of skeletal muscle key glycolytic enzyme 6-phosphofructo-1-kinase: A structural mechanism for PFK allosteric regulation. Archives of biochemistry and biophysics, vol.467, no.2, 275-282.
Luther, Michael A., Cai, Guang Zuan, Lee, James C.. Thermodynamics of dimer and tetramer formations in rabbit muscle phosphofructokinase. Biochemistry, vol.25, no.24, 7931-7937.
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Hesterberg, Lyndal K., Lee, James C.. Sedimentation study of a catalytically active form of rabbit muscle phosphofructokinase at pH 8.55. Biochemistry, vol.19, no.10, 2030-2039.
Costa Leite, Tiago, Da Silva, Daniel, Guimarães Coelho, Raquel, Zancan, Patricia, Sola-Penna, Mauro. Lactate favours the dissociation of skeletal muscle 6-phosphofructo-1-kinase tetramers down-regulating the enzyme and muscle glycolysis. The Biochemical journal, vol.408, no.1, 123-130.
Marcondes, M.C., Sola-Penna, M., Zancan, P.. Clotrimazole potentiates the inhibitory effects of ATP on the key glycolytic enzyme 6-phosphofructo-1-kinase. Archives of biochemistry and biophysics, vol.497, no.1, 62-67.
Marinho-Carvalho, Monica M., Costa-Mattos, Pedro Victor, Spitz, Guilherme A., Zancan, Patricia, Sola-Penna, Mauro. Calmodulin upregulates skeletal muscle 6-phosphofructo-1-kinase reversing the inhibitory effects of allosteric modulators. Biochimica et biophysica acta. Proteins and proteomics, vol.1794, no.8, 1175-1180.
Spitz, Guilherme A., Furtado, Cristiane M., Sola-Penna, Mauro, Zancan, Patricia. Acetylsalicylic acid and salicylic acid decrease tumor cell viability and glucose metabolism modulating 6-phosphofructo-1-kinase structure and activity. Biochemical pharmacology, vol.77, no.1, 46-53.
Hers, H G, Van Schaftingen, E. Fructose 2,6-bisphosphate 2 years after its discovery. The Biochemical journal, vol.206, no.1, 1-12.
Beitner, R.. Control of glycolytic enzymes through binding to cell structures and by glucose-1,6-bisphosphate under different conditions. The role of Ca2+ and calmodulin. The International journal of biochemistry, vol.25, no.3, 297-305.
Zancan, Patricia, Marinho‐Carvalho, Monica M., Faber‐Barata, Joana, Dellias, João M.M., Sola‐Penna, Mauro. ATP and fructose‐2,6‐bisphosphate regulate skeletal muscle 6‐phosphofructo‐1‐kinase by altering its quaternary structure. IUBMB life, vol.60, no.8, 526-533.
Cai, Guang-Zuan, Callaci, Thomas P., Luther, Michael A., Ching Lee, J.. Regulation of rabbit muscle phosphofructokinase by phosphorylation. Biophysical chemistry, vol.64, no.1, 199-209.
Coelho, W.S., Costa, K.C., Sola-Penna, M.. Serotonin stimulates mouse skeletal muscle 6-phosphofructo-1-kinase through tyrosine-phosphorylation of the enzyme altering its intracellular localization. Molecular genetics and metabolism, vol.92, no.4, 364-370.
Harrahy, John J., Malencik, Dean A., Zhao, Zhizhuang, Hisaw, Frederick L., Anderson, Sonia R.. Identification of a New Phosphorylation Site in Cardiac Muscle Phosphofructokinase. Biochemical and biophysical research communications, vol.234, no.3, 582-587.
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Mahrenholz, Alan M., Lan, Linda, Mansour, Tag E.. Phosphorylation of heart phosphofructokinase by protein kinase. Biochemical and biophysical research communications, vol.174, no.3, 1255-1259.
Gomes Alves, Gutemberg, Sola-Penna, Mauro. Epinephrine modulates cellular distribution of muscle phosphofructokinase. Molecular genetics and metabolism, vol.78, no.4, 302-306.
Silva, Daniel Da, Zancan, Patricia, Coelho, Wagner Santos, Gomez, Lilian Sales, Sola-Penna, Mauro. Metformin reverses hexokinase and 6-phosphofructo-1-kinase inhibition in skeletal muscle, liver and adipose tissues from streptozotocin-induced diabetic mouse. Archives of biochemistry and biophysics, vol.496, no.1, 53-60.
Real-Hohn, A., Zancan, P., Da Silva, D., Martins, E.R., Salgado, L.T., Mermelstein, C.S., Gomes, A.M.O., Sola-Penna, M.. Filamentous actin and its associated binding proteins are the stimulatory site for 6-phosphofructo-1-kinase association within the membrane of human erythrocytes. Biochimie, vol.92, no.5, 538-544.
Zancan, Patricia, Sola-Penna, Mauro. Calcium influx: A possible role for insulin modulation of intracellular distribution and activity of 6-phosphofructo-1-kinase in human erythrocytes. Molecular genetics and metabolism, vol.86, no.3, 392-400.
Zancan, Patricia, Sola-Penna, Mauro. Regulation of human erythrocyte metabolism by insulin: Cellular distribution of 6-phosphofructo-1-kinase and its implication for red blood cell function. Molecular genetics and metabolism, vol.86, no.3, 401-411.
Sale, Elizabeth M., White, Morris F., Kahn, C. Ronald. Phosphorylation of glycolytic and gluconeogenic enzymes by the insulin receptor kinase. Journal of cellular biochemistry, vol.33, no.1, 15-26.
Masters, C.. Interactions between glycolytic enzymes and components of the cytomatrix. The Journal of cell biology, vol.99, no.1, 222s-225s.
Lehotzky, A., Telegdi, M., Liliom, K., Ovádi, J.. Interaction of phosphofructokinase with tubulin and microtubules. Quantitative evaluation of the mutual effects. The Journal of biological chemistry, vol.268, no.15, 10888-10894.
Vértessy, Beata G., Kovács, János, Ovádi, Judit. Specific characteristics of phosphofructokinase-microtubule interaction. FEBS letters, vol.379, no.2, 191-195.
Assouline-Cohen, Muriel, Beitner, Rivka. Effects of Ca2+on Erythrocyte Membrane Skeleton-Bound Phosphofructokinase, ATP Levels, and Hemolysis. Molecular genetics and metabolism, vol.66, no.1, 56-61.
Campanella, M. Estela, Chu, Haiyan, Low, Philip S.. Assembly and regulation of a glycolytic enzyme complex on the human erythrocyte membrane. Proceedings of the National Academy of Sciences of the United States of America, vol.102, no.7, 2402-2407.
Messana, Irene, Orlando, Mario, Cassiano, Loredana, Pennacchietti, Lucia, Zuppi, Cecilia, Castagnola, Massimo, Giardina, Bruno. Human erythrocyte metabolism is modulated by the O2-linked transition of hemoglobin. FEBS letters, vol.390, no.1, 25-28.
Silva, Ana Paula P., Alves, Gutemberg G., Araújo, Alexandre H.B., Sola-Penna, Mauro. Effects of insulin and actin on phosphofructokinase activity and cellular distribution in skeletal muscle. Anais da Academia Brasileira de Ciências, vol.76, no.3, 541-548.
Ashkenazy-Shahar, Michal, Ben-Porat, Hanna, Beitner, Rivka. Insulin Stimulates Binding of Phosphofructokinase to Cytoskeleton and Increases Glucose 1,6-Bisphosphate Levels in NIH-3T3 Fibroblasts, Which Is Prevented by Calmodulin Antagonists. Molecular genetics and metabolism, vol.65, no.3, 213-219.
El-Bacha, Tatiana, de Freitas, Marta Sampaio, Sola-Penna, Mauro. Cellular distribution of phosphofructokinase activity and implications to metabolic regulation in human breast cancer. Molecular genetics and metabolism, vol.79, no.4, 294-299.
Meira, Débora Dummer, Marinho-Carvalho, Mônica M., Teixeira, Cesar A., Veiga, Venício F., Da Poian, Andrea T., Holandino, Carla, de Freitas, Marta S., Sola-Penna, Mauro. Clotrimazole decreases human breast cancer cells viability through alterations in cytoskeleton-associated glycolytic enzymes. Molecular genetics and metabolism, vol.84, no.4, 354-362.
Zancan, P., Rosas, A.O., Marcondes, M.C., Marinho-Carvalho, M.M., Sola-Penna, M.. Clotrimazole inhibits and modulates heterologous association of the key glycolytic enzyme 6-phosphofructo-1-kinase. Biochemical pharmacology, vol.73, no.10, 1520-1527.
Penso, Julia, Beitner, Rivka. Detachment of glycolytic enzymes from cytoskeleton of Lewis lung carcinoma and colon adenocarcinoma cells induced by clotrimazole and its correlation to cell viability and morphology. Molecular genetics and metabolism, vol.76, no.3, 181-188.
Penso, Julia, Beitner, Rivka. Clotrimazole decreases glycolysis and the viability of lung carcinoma and colon adenocarcinoma cells. European journal of pharmacology, vol.451, no.3, 227-235.
Penso, Julia, Beitner, Rivka. Lithium detaches hexokinase from mitochondria and inhibits proliferation of B16 melanoma cells. Molecular genetics and metabolism, vol.78, no.1, 74-78.
Gatenby, Robert A., Gillies, Robert J.. Why do cancers have high aerobic glycolysis?. Nature reviews. Cancer, vol.4, no.11, 891-899.
Buschmeier, B, Meyer, H E, Mayr, G W. Characterization of the calmodulin-binding sites of muscle phosphofructokinase and comparison with known calmodulin-binding domains.. The Journal of biological chemistry, vol.262, no.20, 9454-9462.
Marinho-Carvalho, Monica M., Zancan, Patricia, Sola-Penna, Mauro. Modulation of 6-phosphofructo-1-kinase oligomeric equilibrium by calmodulin: Formation of active dimmers. Molecular genetics and metabolism, vol.87, no.3, 253-261.
Glass-Marmor, Lea, Beitner, Rivka. Taxol (paclitaxel) induces a detachment of phosphofructokinase from cytoskeleton of melanoma cells and decreases the levels of glucose 1,6-bisphosphate, fructose 1,6-bisphosphate and ATP. European journal of pharmacology, vol.370, no.2, 195-199.
Glass-Marmor, Lea, Chen-Zion, Malca, Beitner, Rivka. Effects of carbamylcholine and pyridostigmine on cytoskeleton-bound and cytosolic phosphofructokinase and ATP levels in different rat tissues. General pharmacology, vol.27, no.7, 1241-1246.
Schwartz, Devora, Beitner, Rivka. Detachment of the Glycolytic Enzymes, Phosphofructokinase and Aldolase, from Cytoskeleton of Melanoma Cells, Induced by Local Anesthetics. Molecular genetics and metabolism, vol.69, no.2, 159-164.
Vertessy, B. G., Kovacs, J., Low, P., Lehotzky, A., Molnar, A., Orosz, F., Ovadi, J.. Characterization of Microtubule−Phosphofructokinase Complex: Specific Effects of MgATP and Vinblastine. Biochemistry, vol.36, no.8, 2051-2062.
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