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Helicobacter pylori proinflammatory protein up-regulates NF-κB as a cell-translocating Ser/Thr kinase 원문보기

Proceedings of the National Academy of Sciences of the United States of America, v.107 no.50, 2010년, pp.21418 - 21423  

Kim, Do Jin (Department of Chemistry, College of Natural Sciences, Seoul National University, Seoul 151-747, Korea) ,  Park, Kang-Seo ,  Kim, Jung-Ho (Department of Biomedical Science, Graduate School, Kyung Hee University, Seoul 130-701, Korea) ,  Yang, Sang-Hwa ,  Yoon, Ji Young (Department of Biotechnology, College of Life Science and Biotechnology, National Creative Research Initiatives Center for Inflammatory Response Modulation, Yonsei University, Seoul 120-749, Korea) ,  Han, Byeong-Gu ,  Kim, Hyoun Sook (Department of Biotechnology, College of Life Science and Biotechnology, National Creative Research Initiatives Center for Inflammatory Response Modulation, Yonsei University, Seoul 120-749, Korea) ,  Lee, Sang Jae ,  Jang, Jun Young (Department of Chemistry, College of Natural Sciences, Seoul National University, Seoul 151-747, Korea) ,  Kim, Kyoung Hoon ,  Kim, Mi Jung (Cancer Cell and Molecular Biology Branch, Division of Cancer Biology, Research Institute, National Cancer Center, Goyang, Gyeonggi 410-769, Korea) ,  Song, Jin-Su (and) ,  Kim, Hie-Joon (Department of Chemistry, College of Natural Sciences, Seoul National University, Seoul 151-747, Korea) ,  Park, Chung-Mo ,  Lee, Sang-Kyou (Department of Chemistry, College of N) ,  Lee, Byung Il ,  Suh, Se Won

Abstract AI-Helper 아이콘AI-Helper

There has been considerable interest in virulence genes in the plasticity region of Helicobacter pylori , but little is known about many of these genes. JHP940, one of the virulence factors encoded by the plasticity region of H. pylori strain J99, is a proinflammatory protein that induces tumor nec...

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