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Nature protocols, v.6 no.4, 2011년, pp.468 - 481
Gu, Hongcang (Broad Institute, Cambridge, Massachusetts, USA.) , Smith, Zachary D (1] Broad Institute, Cambridge, Massachusetts, USA. [2] Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, Massachusetts, USA. [3] Harvard Stem Cell Institute, Cambridge, Massachusetts, USA.) , Bock, Christoph (1] Broad Institute, Cambridge, Massachusetts, USA. [2] Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, Massachusetts, USA. [3] Harvard Stem Cell Institute, Cambridge, Massachusetts, USA. [4] Max Planck Institute for Informatics, Saarbr체cken, Germany.) , Boyle, Patrick (Broad Institute, Cambridge, Massachusetts, USA.) , Gnirke, Andreas (Broad Institute, Cambridge, Massachusetts, USA.) , Meissner, Alexander (1] Broad Institute, Cambridge, Massachusetts, USA. [2] Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, Massachusetts, USA. [3] Harvard Stem Cell Institute, Cambridge, Massachusetts, USA.)
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Genome-wide mapping of 5-methylcytosine is of broad interest to many fields of biology and medicine. A variety of methods have been developed, and several have recently been advanced to genome-wide scale using arrays and next-generation sequencing approaches. We have previously reported reduced repr...
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