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Human Polycomb protein 2 promotes α-synuclein aggregate formation through covalent SUMOylation

Brain research, v.1381, 2011년, pp.78 - 89  

Oh, Y. (Department of Biology, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749, Republic of Korea) ,  Kim, Y.M. ,  Mouradian, M.M. ,  Chung, K.C.

Abstract AI-Helper 아이콘AI-Helper

Parkinson's disease (PD) manifests from the impairment of motor systems due to the specific loss of dopaminergic neurons and the appearance of intracellular filamentous inclusions called Lewy bodies (LBs). α-Synuclein, a major component of LBs, is known to contribute to the pathoge...

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참고문헌 (48)

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