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Journal of pharmacy and pharmacology, v.63 no.6, 2011년, pp.817 - 824
Tønsberg, Henrik (Department of Pharmaceutics and Analytical Chemistry, Faculty of Pharmaceutical Sciences, University of Copenhagen, Universitetsparken 2, Copenhagen, Denmark) , Holm, René (Department of Preformulation, H.Lundbeck A) , Mu, Huiling (Department of Pharmaceutics and Analytical Chemistry, Faculty of Pharmaceutical Sciences, University of Copenhagen, Universitetsparken 2, Copenhagen, Denmark) , Boll, Jette Bisgaard (Department of Preformulation, H.Lundbeck A) , Jacobsen, Jette (Department of Pharmaceutics and Analytical Chemistry, Faculty of Pharmaceutical Sciences, University of Copenhagen, Universitetsparken 2, Copenhagen, Denmark) , Müllertz, Anette (Department of Pharmaceutics and Analytical Chemistry, Faculty of Pharmaceutical Sciences, University of Copenhagen, Universitetsparken 2, Copenhagen, Denmark)
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AbstractObjectivesThe aim of this study was to examine the effects of bile on the oral absorption of the poorly water-soluble compound, halofantrine, when administered to rats in vehicles consisting of the co-solvent polyethylene glycol 400 (PEG 400) alone or in mixtures with the surfactant polysorb...
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